USP8 抗体
(Ubiquitin Specific Peptidase 8 (USP8))
Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell proliferation. Required to enter into S phase in response to serum stimulation. May regulate T-cell anergy mediated by RNF128 via the formation of a complex containing RNF128 and OTUB1. Probably regulates the stability of STAM2 and RASGRF1. Regulates endosomal ubiquitin dynamics, cargo sorting, membrane traffic at early endosomes, and maintenance of ESCRT-0 stability. The level of protein ubiquitination on endosomes is essential for maintaining the morphology of the organelle. Deubiquitinates EPS15 and controles tyrosine kinase stability. Removes conjugated ubiquitin from EGFR thus regulating EGFR degradation and downstream MAPK signaling. Involved in acrosome biogenesis through interaction with the spermatid ESCRT-0 complex and microtubules. Deubiquitinates BIRC6/bruce and KIF23/MKLP1.
recommended
recommended
recommended
USP8 抗体 by 适用
Find USP8 抗体 for a variety of species such as anti-Human USP8, anti-Mouse USP8, anti-Pig USP8. The species listed below are among those available. Click on a link to go to the corresponding products.
USP8 抗体 by 应用范围
Find USP8 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.
USP8 抗体 by 抗体来源
Find USP8 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
USP8 抗体 by 克隆形成能力
Find available monoclonal or polyclonal USP8 抗体. Click on a link to go to the corresponding products.
USP8 抗体 by 克隆
Find USP8 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
USP8 抗体 by 标记
Find USP8 抗体 with a specific conjugate such as APC, Biotin, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular USP8 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p), IP, ICC
Validations
- (4)
Cat. No.
ABIN2855692
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7174360
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
Cat. No.
ABIN6150035
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IF
Validations
- (1)
Cat. No.
ABIN7262975
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Chicken, Human, Monkey
Application
WB
Validations
- (1)
Cat. No.
ABIN6745387
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Human, Pig
Application
WB
Validations
- (1)
Cat. No.
ABIN6745282
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (2)
Cat. No.
ABIN1872156
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN388891
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), EIA
Validations
- (2)
Cat. No.
ABIN357535
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
Cat. No.
ABIN6760044
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
Cat. No.
ABIN7571933
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IHC (fp)
Validations
Cat. No.
ABIN7454885
Quantity
20 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP
Validations
Cat. No.
ABIN7452552
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA
Validations
Cat. No.
ABIN2570139
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our USP8 抗体
: "Mutations in the deubiquitinase gene USP8 cause Cushing's disease." in: Nature genetics, Vol. 47, Issue 1, pp. 31-8, (2014) (PubMed).: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
: "Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease." in: Oncogene, Vol. 20, Issue 29, pp. 3869-79, (2001) (PubMed).
Aliases for USP8 抗体
ubiquitin carboxyl-terminal hydrolase 8 (LOC9310109) 抗体ubiquitin carboxyl-terminal hydrolase 8 (MGYG_00369) 抗体
ubiquitin specific peptidase 8 (USP8) 抗体
ubiquitin specific peptidase 8 (Usp8) 抗体
AI574262 抗体
AW557536 抗体
HumORF8 抗体
mKIAA0055 抗体
UBPY 抗体
Ubpy 抗体
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