anti-Ubiquitin Specific Peptidase 25 (USP25) 抗体

Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. 再加上,我们可以发USP25 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
USP25 29761 Q9UHP3
USP25 304150  
USP25 30940 P57080
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antibodies-online.cn销售最多的anti-USP25 抗体

Showing 10 out of 76 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 EIA, WB 0.4 mL 6至8个工作日
非结合性 EIA, IHC (p), WB 0.4 mL 6至8个工作日
非结合性 WB 100 μg 2至3个工作日
非结合性 IHC, WB Western blot analysis of extracts of various cells, using USP25 antibody. Immunohistochemistry of paraffin-embedded mouse heart using USP25 antibody at dilution of 1:100 (x40 lens). 100 μL 11至13个工作日
小鼠 非结合性 WB 100 μL 11至13个工作日
非结合性 ELISA, IF, IHC (p), WB   0.1 mg 2至3个工作日
非结合性 WB Western blot analysis of extracts of BxPC-3 cells, using USP25 antibody (ABIN5970690). 100 μL 11至16个工作日
非结合性 IHC, ELISA, WB   100 μL 11至14个工作日
非结合性 ELISA, IF, IHC, IHC (p), WB   0.05 mg 11至14个工作日
非结合性 IHC (p), WB Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Western Blot analysis of (1) Human RT-4 cell, (2) Human U-251MG sp cell. 100 μL 11至12个工作日

引用最多的anti-USP25 抗体

  1. Human Polyclonal USP25 Primary Antibody for ELISA, WB - ABIN545139 : Groet, Ives, Jones, Danton, Flomen, Sheer, Hrascan, Pavelic, Nizetic: Narrowing of the region of allelic loss in 21q11-21 in squamous non-small cell lung carcinoma and cloning of a novel ubiquitin-specific protease gene from the deleted segment. in Genes, chromosomes & cancer 2000 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal USP25 Primary Antibody for IHC (p), ELISA - ABIN545140 : Valero, Marfany, González-Angulo, González-González, Puelles, Gonzàlez-Duarte: USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2. in Genomics 2000 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Polyclonal USP25 Primary Antibody for WB - ABIN5663921 : Zhong, Wang, Fang, Zhang, Luo, Shang, Ouyang, Ouyang, Chen, Xiao: Ubiquitin-specific proteases 25 negatively regulates virus-induced type I interferon signaling. in PLoS ONE 2013 (PubMed)

  4. Human Polyclonal USP25 Primary Antibody for ICC, IF - ABIN4364571 : Habtemichael, Li, Alcázar-Román, Westergaard, Li, Petersen, Li, DeVries, Li, Julca-Zevallos, Wolenski, Bogan: Usp25m protease regulates ubiquitin-like processing of TUG proteins to control GLUT4 glucose transporter translocation in adipocytes. in The Journal of biological chemistry 2019 (PubMed)


Human Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. Polymorphism of SREBF1 gene rs11868035 may increase susceptibility to Parkinson's disease in the northeastern Chinese population, while variant of USP25 gene rs2823357 may have no association with susceptibility to Parkinson's disease in northeastern Chinese.

  2. These findings indicate that USP25 promotes stability of HBO1 in bacterial infection thereby enhances HBO1-mediated inflammatory gene transcription.

  3. the high stabilization of tankyrases in cultured cells by ectopic expression of a constitutive dimer of USP25 supports a biological relevance of this tetramerization/inhibition mechanism.

  4. Smurf1 overexpression decreases USP25 protein turnover, and the E3 ligase enzymatic activity of Smurf1 is required for USP25 degradation.

  5. USP25 directly interacted with tankyrases to promote their deubiquitination and stabilization and demonstrated that USP25 deficiency could promote the degradation of tankyrases and consequent stabilization of Axin to antagonize Wnt signaling

  6. Results suggest inhibition of Usp25's catalytic activity upon the non-covalent binding of SUMO2 to the Usp25 SUMO-interacting motif, and found that SUMO2 can competitively block the interaction between the Usp25 ubiquitin-binding region and its ubiquitin substrates.

  7. We detected SNPs at USP25 with associations of genome-wide significance for Inflammatory Bowel Disease.

  8. REM Sleep Behavior Disorder patients with homozygous USP25 rs2823357 progressed to synucleinopathies faster than others.

  9. Findings suggest that ubiquitin-specific protease 25 (USP25) as a VRK2 substrate that acts on TRiC deubiquitination.

  10. These findings indicate that miR-200c exerts tumor-suppressive effects for NSCLC through the suppression of USP25 expression and suggests a new therapeutic application of miR-200c in the treatment of NSCLC.

  11. USP25 is a novel deubiquitinating enzyme negatively regulating virus-induced interferon-beta production.

  12. a model where USP25 counteracts ubiquitination of ERAD substrates by the ubiquitin ligase HRD1, rescuing them from degradation by the proteasome.

  13. Studies indicate that DUBs recycle ubiquitin by processing polyubiquitin chains to generate free ubiquitin, and can be regulated by ubiquitination or phosphorylation.

  14. the second SH2 domain of SYK physically interacts with a tyrosine-rich, C-terminal region of USP25 independently of tyrosine phosphorylation

  15. characterization of alternatively spliced products and tissue-specific isoforms

  16. downregulation of USP25 gene in human lung cancer

  17. Seven amino acids in the SIM of USP25 are sufficient for SUMO2/3-specific binding and conjugation

  18. Data show that USP25m is regulated through alternative conjugation of ubiquitin (activating) or SUMO (inhibiting) to the same lysine residue (K99), which may promote the interaction with distinct intramolecular regulatory domains.

Mouse (Murine) Ubiquitin Specific Peptidase 25 (USP25) interaction partners

  1. The overexpression of TRAF3 attenuated the proinflammatory effects of USP25 knockdown in tolerized Kupffer cells.

  2. IRF7 directly binds to the two conserved IRF binding sites on the USP25 promoter to drive transcription of Usp25.

  3. Data show that the degradation of TNF receptor-associated factor 3 (TRAF3) and TNF receptor-associated Ffactor 6 (TRAF6) was accelerated in ubiquitin-specific protease 25 knockout (USP25-/-) cells after viral infection.

  4. inhibiting the degradation of TRAF3 during TLR4 activation, USP25 enables a balanced innate immune response.

  5. USP25 is a deubiquitinating enzyme (DUB) that negatively regulates IL-17-triggered signaling.

USP25 抗原简介


Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999

Gene names and symbols associated with USP25

  • ubiquitin specific peptidase 25 (USP25) 抗体
  • universal stress protein UspA (RR_RS03930) 抗体
  • ubiquitin specific peptidase 25 (usp25) 抗体
  • ubiquitin specific peptidase 25 L homeolog (usp25.L) 抗体
  • ubiquitin specific peptidase 25 (Usp25) 抗体
  • MGC81666 抗体
  • USP21 抗体
  • usp25 抗体
  • wu:fi33c05 抗体
  • wu:fo67e06 抗体
  • wu:fp97a04 抗体
  • zgc:55791 抗体

Protein level used designations for USP25

ubiquitin specific peptidase 25 , ubiquitin carboxyl-terminal hydrolase 25-like , universal stress protein , ubiquitin carboxyl-terminal hydrolase 25 , ubiquitin specific protease 25 , USP on chromosome 21 , deubiquitinating enzyme 25 , ubiquitin thioesterase 25 , ubiquitin thiolesterase 25 , ubiquitin-specific processing protease 25 , ubiquitin-specific-processing protease 25 , mUSP25

100458885 Pongo abelii
478387 Canis lupus familiaris
524531 Bos taurus
716923 Macaca mulatta
3127262 Haloarcula marismortui ATCC 43049
100083895 Ornithorhynchus anatinus
100348335 Oryctolagus cuniculus
100393986 Callithrix jacchus
406790 Danio rerio
418471 Gallus gallus
446581 Xenopus laevis
473918 Pan troglodytes
733977 Xenopus (Silurana) tropicalis
100229974 Taeniopygia guttata
100546482 Meleagris gallopavo
100628105 Sus scrofa
29761 Homo sapiens
304150 Rattus norvegicus
30940 Mus musculus
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