Use your antibodies-online credentials, if available.
Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. 再加上，我们可以发UBXN6 蛋白 (5)和数多这个蛋白质的别的产品。
Showing 10 out of 50 products:
Upon damage, p97 (显示 EIF4G2 抗体) translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA (显示 PLAA 抗体), and the deubiquitinating enzyme YOD1 (显示 YOD1 抗体), which we term ELDR components for Endo-Lysosomal Damage Response.
UBXD1-N intercalates into the p97 (显示 EIF4G2 抗体)-ND1 (显示 MT-ND1 抗体) interface, thereby modulating interdomain communication of p97 (显示 EIF4G2 抗体) domains and its activity with relevance for disease pathogenesis
Data indicate that endosomal trafficking of CAV1 (显示 CAV1 抗体) depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP (显示 vcp 抗体)-UBXD1.
UBXD1 modulates the trafficking of ERGIC-53 (显示 LMAN1 抗体)-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53 (显示 LMAN1 抗体).
Data show that expression of VCP (显示 vcp 抗体) mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 (显示 CAV1 抗体) transport at the limiting membrane of enlarged endosomes in cultured cells.
UBXD1 is a novel co-factor of the human p97 ATPase (显示 vcp 抗体).
An additional p97 (显示 EIF4G2 抗体) binding site in UBXD1 that competed with the p47 (显示 ING1 抗体) cofactor for binding to the N domain of p97 (显示 EIF4G2 抗体) was identified.
these findings suggest that UBXD1 is a regulatory component of endoplasmic reticulum-associated degradation that may modulate the adaptor binding to VCP.
Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).
UBX domain containing 1
, UBX domain-containing protein 6
, UBX domain protein 6
, UBX domain-containing 1
, UBX domain-containing 2
, UBX domain-containing protein 1