Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) ELISA试剂盒

TNFRSF18 encodes a member of the TNF-receptor superfamily. 再加上,我们可以发TNFRSF18 抗体 (295)TNFRSF18 蛋白 (42)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TNFRSF18 21936 O35714
TNFRSF18 8784 Q9Y5U5
大鼠 TNFRSF18 TNFRSF18 500598  
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
10pg/mL 62.5-4000 pg/mL Human TNFRSF18/GITR PicoKine ELISA Kit standard curve 96 Tests Log in to see 4至6个工作日
$369.00
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小鼠 10pg/mL 62.5-4000 pg/mL Mouse TNFRSF18/GITR PicoKine ELISA Kit standard curve 96 Tests Log in to see 4至6个工作日
$369.00
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引用最多的TNFRSF18 ELISA试剂盒

  1. Human TNFRSF18 ELISA Kit for Sandwich ELISA - ABIN624986 : Gan, Feng, Gu, Tan, Sun, Lv, Zhang: Correlation of increased blood levels of GITR and GITRL with disease severity in patients with primary Sjögren's syndrome. in Clinical & developmental immunology 2013 (PubMed)

适于 TNFRSF18 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. These results suggest that therapeutically targeting GITR represents a unique approach to cancer immunotherapy and suggests that a multimeric fusion protein may provide increased agonistic potential versus an antibody

  2. These findings support further study into combination partners for GITRL (显示 TNFSF18 ELISA试剂盒)-FP that may augment CD8 (显示 CD8A ELISA试剂盒) T-cell priming as well as provide hypotheses that can be tested in human clinical trials exploring GITR agonists including GITRL (显示 TNFSF18 ELISA试剂盒)-FP.

  3. Expression of human GITR was comparable with that of mouse GITR in tumor-infiltrating Tregs despite being drastically lower in other human TILs and in many human peripheral blood populations.

  4. anti-GITR mAb shifts Treg populations to enable immune attack on tumors, with clinical implications for molecular markers to modify emerging treatments.

  5. Continuous GITR stimulation through B cell Gitrl (显示 TNFSF18 ELISA试剂盒) acts protective in a mouse model of atherosclerosis by regulating the balance between regulatory and effector memory CD4 (显示 CD4 ELISA试剂盒)(+) T cells.

  6. these results indicate that blockade of GITR signaling can ameliorate arthritis progression mainly by modulating the follicular helper T cell response

  7. GITR appears as a potential target for intervention during infection by the parasite Toxoplasma gondii, even though further studies are still necessary to better characterize the immune response triggered by GITR activation during T. gondii infection

  8. our data suggest a critical role for GITR in Treg cell homeostasis and indicate that Ptpn22 (显示 PTPN22 ELISA试剂盒) independently affects the differentiation status of Treg cells and their homeostatic behavior

  9. These findings provide further support for the continued development of agonist anti-GITR antibodies as an immunotherapeutic strategy for osteosarcoma. We suggest that our proposed immunotherapy could be developed further to improve osteosarcoma treatment

  10. Th9 cells and iTregs are developmentally linked and GITR can subvert tolerogenic conditions to boost Th9 immunity.

Human Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 (显示 FOXP3 ELISA试剂盒) and GITR

  2. a novel molecular mechanism by which MBD4 inhibits GITR expression in a DNMT1 (显示 DNMT1 ELISA试剂盒)-dependent manner

  3. Aberrant expression of GITR may contribute to systemic lupus erithematosus pathogenesis. Glucocorticoid may achieve its therapeutic effect partly by inducing GITR expression on Tresps rather than Tregs, which initiates the apoptosis of Tresp cells in SLE patients.

  4. GITR expression can enhance the sensitivity to Bortezomib by inhibiting Bortezomib-induced NF-kappaB (显示 NFKB1 ELISA试剂盒) activation.

  5. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  6. Data may suggest a key role of regulatory GITR+CD25 (显示 IL2RA ELISA试剂盒) low/-CD4 (显示 CD4 ELISA试剂盒)+ T cells subset in the modulation of the abnormal immune response in lupus erythematosus (SLE) patients.

  7. results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.

  8. these results show a higher susceptibility to apoptosis in patients' versus controls' T(reg) cells, suggesting that GITR is a T(reg)-cell marker that would be primarily involved in T(reg)-cell survival rather than in their suppressor function.

  9. Our findings indicate the possible involvement of GITR-GITRL (显示 TNFSF18 ELISA试剂盒) pathway in the pathogenesis of pSS (显示 CDSN ELISA试剂盒).

  10. GITR acts as a potential tumor suppressor in MM.

TNFRSF18 抗原简介

Antigen Summary

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFRSF18

  • TNF receptor superfamily member 18 (TNFRSF18) 抗体
  • tumor necrosis factor receptor superfamily, member 18 (Tnfrsf18) 抗体
  • TNF receptor superfamily member 18 (Tnfrsf18) 抗体
  • AITR 抗体
  • CD357 抗体
  • Gitr 抗体
  • GITR-D 抗体
  • TNFRSF18 抗体

Protein level used designations for TNFRSF18

tumor necrosis factor receptor superfamily member 18 , glucocorticoid-induced TNFR-related , tumor necrosis factor receptor superfamily, member 18 , glucocorticoid-induced TNFR-related protein , TNF receptor superfamily activation-inducible protein , activation-inducible TNFR family receptor

GENE ID SPECIES
419424 Gallus gallus
516256 Bos taurus
606971 Canis lupus familiaris
699559 Macaca mulatta
741567 Pan troglodytes
21936 Mus musculus
8784 Homo sapiens
500598 Rattus norvegicus
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