anti-Troponin T2, Cardiac (TNNT2) 抗体

The protein encoded by TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. 再加上,我们可以发Cardiac Troponin T2 试剂盒 (95)Cardiac Troponin T2 蛋白 (33)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TNNT2 7139 P45379
TNNT2 21956 P50752
TNNT2 24837 P50753
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antibodies-online.cn销售最多的anti-Cardiac Troponin T2 抗体

Showing 10 out of 379 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-TNNT2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Muscle Host:  Mouse  Target Name:  TNNT2  Sample Tissue:  Mouse Skeletal Muscle  Antibody Dilution:  1ug/ml 100 μL Log in to see 2至3个工作日
$319.00
详细
非结合性 WB Western blot analysis of cTnT expression in H9 (A), 4T1 (B), human heart (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$429.84
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山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
$429.84
详细
非结合性 EIA, WB TNNT2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNNT2 antibody detected the TNNT2 protein (arrow). 0.4 mL Log in to see 6至8个工作日
$484.00
详细
小鸡 小鼠 非结合性 IF, IHC, IHC (p) Human Rabbit Heart (formalin-fixed, paraffin-embedded) stained with TNNT2 antibody ABIN462337 followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Anti-TNNT2 / CTnT antibody IHC of human rabbit heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50. 50 μL Log in to see 11至14个工作日
$484.00
详细
Cat 小鼠 非结合性 EIA, IHC (p), IP, WB 50 μg Log in to see 6至8个工作日
$495.00
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小鸡 小鼠 非结合性 IF, IHC, IHC (p) Anti-TNNT2 / Cardiac Troponin T antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml. 250 μL Log in to see 11至14个工作日
$786.50
详细
小鼠 非结合性 FACS, ELISA, WB 100 μL Log in to see 11至16个工作日
$469.05
详细
Cat 小鼠 非结合性 ELISA, IHC, IHC (p) Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TNNT2 / CTnT antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11至14个工作日
$484.00
详细

引用最多的anti-Cardiac Troponin T2 抗体

  1. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for ICS - ABIN2688864 : Jáchymová, Muravská, Paleček, Kuchynka, Řeháková, Magage, Kr��l, Zima, Horký, Linhart: Genetic variation screening of TNNT2 gene in a cohort of patients with hypertrophic and dilated cardiomyopathy. in Physiological research / Academia Scientiarum Bohemoslovaca 2012 (PubMed)
    Show all 7 Pubmed References

  2. Chicken Monoclonal Cardiac Troponin T2 Primary Antibody for IHC (f), ICS - ABIN2688865 : Lian, Hsiao, Wilson, Zhu, Hazeltine, Azarin, Raval, Zhang, Kamp, Palecek: Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 7 Pubmed References

  3. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA - ABIN263479 : Feng, Taggart, Hall, Bryant, Sansone, Kemmerer, Herlich, Lord: Limited additional release of cardiac troponin I and T in isoproterenol-treated beagle dogs with cardiac injury. in Clinical chemistry 2005 (PubMed)
    Show all 6 Pubmed References

  4. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA (Detection), ELISA - ABIN191347 : Goette, Arndt, Röcken, Staack, Bechtloff, Reinhold, Huth, Ansorge, Klein, Lendeckel: Calpains and cytokines in fibrillating human atria. in American journal of physiology. Heart and circulatory physiology 2002 (PubMed)
    Show all 6 Pubmed References

  5. Fish Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA, WB - ABIN191342 : Hammerer-Lercher, Erlacher, Bittner, Korinthenberg, Skladal, Sorichter, Sperl, Puschendorf, Mair: Clinical and experimental results on cardiac troponin expression in Duchenne muscular dystrophy. in Clinical chemistry 2001 (PubMed)
    Show all 6 Pubmed References

  6. Human Polyclonal Cardiac Troponin T2 Primary Antibody for IP, IHC - ABIN191343 : Nakaura, Morimoto, Yanaga, Nakata, Nishi, Imaizumi, Ohtsuki: Functional changes in troponin T by a splice donor site mutation that causes hypertrophic cardiomyopathy. in The American journal of physiology 1999 (PubMed)
    Show all 6 Pubmed References

  7. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA - ABIN263477 : Urasawa, Wada, Machida, Yuasa, Shimatsu, Wakao, Yuasa, Sano, Nonaka, Nakamura, Takeda: Selective vacuolar degeneration in dystrophin-deficient canine Purkinje fibers despite preservation of dystrophin-associated proteins with overexpression of Dp71. in Circulation 2008 (PubMed)
    Show all 6 Pubmed References

  8. Human Monoclonal Cardiac Troponin T2 Primary Antibody for ELISA (Capture), ELISA - ABIN263480 : van den Berg, Abu-Issa, de Boer, Hutson, de Boer, Soufan, Ruijter, Kirby, van den Hoff, Moorman: A caudal proliferating growth center contributes to both poles of the forming heart tube. in Circulation research 2009 (PubMed)
    Show all 6 Pubmed References

更多抗Cardiac Troponin T2的相互作用对抗体

Human Troponin T2, Cardiac (TNNT2) interaction partners

  1. The increase in TnT during Immersion pulmonary edemamay be secondary to the release of troponin from non-cardiac origin. The measurement of TnI in place of TnT permits in some cases to avoid additional examinations, especially unnecessary invasive investigations

  2. Serum levels of troponin T (and troponin I) are related to heart failure and left ventricular hypertrophy in hemodialysis patients.

  3. [Pulsed electric fields inhibit tumor growth but induce myocardial injury of melanoma-bearing mice].

  4. review exploring mechanisms that may lead to cTn elevations

  5. NT-proBNP and hs-cTnT are useful biomarkers in assessment of hypertrophy and fibrosis in hypertrophic cardiomyopathy.

  6. Data suggest that clinical characteristics can be used to identify low risk patients with acute chest pain and Normal high sensitivity cardiac troponin (hs-cTn) levels.

  7. Troponin-T mutation is associated with Hypertrophic cardiomyopathy.

  8. These data suggest that associations of high-sensitivity cardiac troponin I and high-sensitivity cardiac troponin T with cardiac injury detected by electrocardiography are driven by different mechanisms.

  9. Serum cardiac troponin T associated with cardiovascular complications after heart transplantation.

  10. Troponin T is neither specific nor useful as cardiac biomarker for post mortem sample

  11. Data show that the incident atrial fibrillation (AF) occurrence group had similar baseline troponin I (TnI) levels, but higher troponin T (TnT) levels [Review and Meta-Analysis].

  12. Cardiac troponin T is the key diagnostic marker in Non-ST elevated myocardial infarction (NSTEMI).

  13. the optimal cutoff-value of hs-TnT to improve diagnostic accuracy of acute myocardial infarction in chronic kidney disease patients, was determined.

  14. This study has confirmed the higher reference levels of hscTnT in neonates and young infants when compared with adult population

  15. The current results indicate that patients with nondipper hypertension (NDH) had higher high-sensitivity - cTnT levels than the patients with dipper hypertension. High-sensitivity -cTnT was an independent predictor of NDH and was significantly related with nondipping status.

  16. Studies indicate that in patients with end-stage renal disease (ESRD), elevation of cardiac-specific troponin T (cTnT) was more frequent than elevation of troponin I (cTnI) [Review].

  17. Data suggest that high sensitivity cardiac troponin (hs-cTnT) may help predict whether non-acute coronary syndrome (ACS) emergency department (ED) patients have a final non-ACS cardiac or non-cardiac/unknown origin diagnoses.

  18. Cardiac troponin T at the NMJ region contributes to NMJ functional decline with ageing mainly in the fast-twitch skeletal muscle through interfering with PKA signalling.

  19. On admission, high-sensitivity-troponin T/creatine kinase-MB ratio was significantly higher in takotsubo syndrome patients compared to myocardial infarction patients.

  20. Serum high-sensitivity cardiac troponin T (HS-cTnT) level is high and associated with carotid plaques in systemic lupus erythematous (SLE) patients.

Mouse (Murine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Cardiac troponin T at the NMJ region contributes to NMJ functional decline with ageing mainly in the fast-twitch skeletal muscle through interfering with PKA signalling.

  2. Hypertrophic cardiomyopathy pathophysiology is "mutation specific" in mice models carrying TNNT2 E163R and R92Q mutations.

  3. TnTA30V mutation attenuated Ca(2+)-activated maximal tension and length-mediated cross-bridge recruitment against alpha-myosin heavy chain but augmented these parameters against beta-myosin heavy chain, suggesting divergent contractile phenotypes.

  4. The shift from cTnT exon 5 inclusion to exclusion during development was delayed in the heart of Ts65Dn mice due to Dyrk1A overexpression.

  5. for hypertrophic cardiomyopathy (HCM)-causing mutations in TnT, Ca(2+)-sensitisation together with uncoupling in vitro is the usual response and both factors may contribute to the HCM phenotype

  6. cardiomyopathy mutation (R97L) in mouse cardiac troponin T has an effect on the muscle length-mediated recruitment of crossbridges and is modified divergently by alpha- and beta-myosin heavy chain

  7. Data indicate that high-sensitivity troponin T (hs-TnT) levels are influenced by myocardial dysfunction/heart failure (HF) in acute exacerbation of chronic obstructive lung disease (AECOPD), but provide independent prognostic information.

  8. cTnT elevation emerged as a strong, independent predictor of 30-day mortality and remained a modest, but significant, predictor throughout 2 years post transcatheter aortic valve implantation.

  9. MBPC and troponin-I phosphorylation modulate myofilament length-dependent activation

  10. Data indicate that the troponin T Tnnt2(MerCreMer/+) mouse model also provides a useful tool to trace myocardial lineage during development.

  11. TnT mutation F72L leads to contractile changes that are linked to dilated cardiomyopathy in the presence of MYH6 and hypertrophic cardiomyopathy in the presence of MYH7.

  12. TNT increases slightly during low flux-hemodialysis. High-flux hemodialysis eliminates the biomarker and can mask increases caused by cardiac disease.

  13. Dominant negative TnI-TnT interface mutation decreases the binding affinity of cTnI for TnT, causes early ventricular remodeling, and blunts the beta-adrenergic response of cardiac myocytes.

  14. Mice carrying the Delta160E or E163R mutations exhibit sarcomeric disruption.

  15. Cardiac muscle activation blunted by a mutation to the regulatory component, troponin T.

  16. Study is the first to show that the interplay between the N terminus of cTnT and the overlapping ends of contiguous Tm effectuates different states of Tm on the actin filament.

  17. We conclude that the observed clinical severity of the cTnT Delta160E mutation is caused by a combination of direct sarcomeric disruption coupled to a profound dysregulation of Ca(2+) homeostasis

  18. Report two distinct functional regions within the N-terminus of cTnT with divergent roles in mediating cardiac contractile activation.

  19. Data show that cardiac TnI gene transition and the alternatively spliced cardiac TnT isoform switching occur in postnatal pulmonary vein.

  20. findings provide new evidence to demonstrate that R92 mutation effects on cardiac contractile function and dynamics are influenced by myosin heavy chain isoform

Zebrafish Troponin T2, Cardiac (TNNT2) interaction partners

  1. Data showed that CXCR4a was significantly more highly expressed in tnnt2 knocked down mutant at 48 and 60 hpf than controls.

  2. We show that the zebrafish silent heart (sih) mutation affects the gene tnnt2.

  3. Tnnt1, Tnnt2, and Tnnt3b were conserved in the central tropomyosin- and C-terminal troponin I-binding domains but the N-terminal hypervariable regions were highly extended and rich in glutamic acid in polypeptides of Tnnt1 and Tnnt2, but not Tnnt3b.

Cow (Bovine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. Significant changes in thin filament Ca2+-sensitivity, structure and kinetics are brought about through PKC phosphorylation of cardiac troponin T.

  2. The mu-calpain-mediated proteolytic modification of TnT by removing the NH2-terminal variable region of TnT may act as an acute mechanism to adjust muscle contractility under stress conditions.

Pig (Porcine) Troponin T2, Cardiac (TNNT2) interaction partners

  1. We show that the phosphorylation of cTnI and alphaTm vary in the different chambers of the heart, whereas the phosphorylation of MLC2 and cTnT does not.

Rabbit Troponin T2, Cardiac (TNNT2) interaction partners

  1. Substituting smooth muscle caldesmon for skeletal muscle troponin produces a similar decrease and re-increase in fluorescence, but the apparent rate constant for the increase is >10 times that observed with troponin.

  2. In ischemic myocardium, the expression of cTnT showed prominent focal or flaky depletion in myocardial cytoplasm with no expression detected in interstitium.

Cardiac Troponin T2 (TNNT2) 抗原简介

蛋白简介

The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.

Gene names and symbols associated with TNNT2

  • troponin T2, cardiac type (TNNT2) 抗体
  • troponin T2, cardiac (Tnnt2) 抗体
  • troponin T2, cardiac type (Tnnt2) 抗体
  • troponin T type 2a (cardiac) (tnnt2a) 抗体
  • troponin T2, cardiac type L homeolog (tnnt2.L) 抗体
  • troponin T2e, cardiac (tnnt2e) 抗体
  • CMH2 抗体
  • CMPD2 抗体
  • CT3 抗体
  • cTnT 抗体
  • Ctt 抗体
  • CTTG 抗体
  • LVNC6 抗体
  • RATCTTG 抗体
  • RCM3 抗体
  • si:ch211-136g2.1 抗体
  • tnnt2 抗体
  • Tnnt3 抗体
  • Tnt 抗体
  • TnTC 抗体

Protein level used designations for TNNT2

cardiomyopathy, dilated 1D (autosomal dominant) , cardiomyopathy, hypertrophic 2 , troponin T, cardiac muscle , troponin T2, cardiac , cardiac TnT , cardiac muscle troponin T , tnTc , Troponin T cardiac , cTnT , cardiac troponin T2 , sih , silent heart , cardiac troponin T form I , tnTC , troponin T, cardiac muscle isoforms , cardiac troponin T , troponin T type 2, cardiac , cardiac troponin 2 , Troponin T, cardiac muscle , troponin T cardiac isoform , novel slow skeletal troponin T family protein , troponin T2e, cardiac

GENE ID SPECIES
7139 Homo sapiens
21956 Mus musculus
24837 Rattus norvegicus
58071 Danio rerio
286816 Bos taurus
396433 Gallus gallus
403532 Canis lupus familiaris
493940 Felis catus
100379561 Cavia porcellus
398518 Xenopus laevis
100622450 Sus scrofa
100009428 Oryctolagus cuniculus
556703 Danio rerio
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