anti-Tropomyosin 3 (TPM3) 抗体

TPM3 encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. 再加上,我们可以发TPM3 蛋白 (16)TPM3 试剂盒 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TPM3 7170 P06753
TPM3 59069 P21107
TPM3 117557 Q63610
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Showing 10 out of 35 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-TPM3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Log in to see 2至3个工作日
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: tropomyosin-3 Antibody  - Staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Western Blot: tropomyosin-3 Antibody  - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II. 0.1 mL Log in to see 10至13个工作日
非结合性 IF, IHC, WB Western blot analysis of extracts of various tissues, using TPM3 antibody. 100 μL Log in to see 16 Days
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. Figure.DAB staining on IHC-P. Samples: Human Tissue 100 μg Log in to see 13至16个工作日
小鼠 非结合性 IHC (p), ELISA, WB Anti-TPM3 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104792 dilution 20 ug/ml. 50 μg Log in to see 7至9个工作日
小鼠 非结合性 ELISA, WB TPM3 polyclonal antibody (A01), Lot # Abnova060503QCS1 Western Blot analysis of TPM3 expression in HeLa . TPM3 polyclonal antibody (A01), Lot # Abnova060503QCS1. Western Blot analysis of TPM3 expression in NIH/3T3. 50 μL Log in to see 11至12个工作日
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
非结合性 WB Tropomyosin 3 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 2至3个工作日
非结合性 WB Western Blot: tropomyosin-3 Antibody [NBP1-57472] - THP-1 cell lysate, concentration 0.2-1 ug/ml. 100 μL Log in to see 8至11个工作日

通过反应活性、应用领域、克隆类型和共轭标记 TPM3 抗体

特性 应用范围 宿主 克隆类型
, ,
Mouse (Murine)
, ,
Rat (Rattus)

引用最多的anti-TPM3 抗体

  1. Human Polyclonal TPM3 Primary Antibody for IHC, IHC (p) - ABIN4362650 : Singleton, Rouhi, Zois, Haider, Li, Kessler, Cao, Harris: Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis. in Oncogene 2014 (PubMed)

  2. Human Monoclonal TPM3 Primary Antibody for IHC (p), ELISA - ABIN521063 : Doukhanine, Gavino, Haines, Almazan, Richard: The QKI-6 RNA binding protein regulates actin-interacting protein-1 mRNA stability during oligodendrocyte differentiation. in Molecular biology of the cell 2010 (PubMed)

  3. Cow (Bovine) Polyclonal TPM3 Primary Antibody for WB - ABIN2776646 : Ramsey, Clarke, Roberts, Sullivan, Johnson, Liu: An economic evaluation of atorvastatin for primary prevention of cardiovascular events in type 2 diabetes. in PharmacoEconomics 2008 (PubMed)
    Show all 2 Pubmed References


Zebrafish Tropomyosin 3 (TPM3) interaction partners

  1. This work uncovers a Quaking/Tpm3 pathway controlling de novo myofibril assembly.

Human Tropomyosin 3 (TPM3) interaction partners

  1. Analysis of the residual, resected tumor identified a chromoplectic TPM3-ALK rearrangement that involved many other known oncogenes and was confirmed by rtPCR.

  2. expression levels of tropomyosin 3 (TPM3) were higher in stage III ESCC tissue compared with stage I (P<0.05). The findings of the present study identified twelve proteins, which are closely associated with ESCC invasion and metastasis, apoptosis and cell signal transduction.

  3. Dominant mutations in TPM3, encoding alpha-tropomyosinslow, cause a congenital myopathy characterized by generalized muscle weakness. Here, we used a multidisciplinary approach to investigate the mechanism of muscle dysfunction in 12 TPM3-myopathy patients.

  4. This work expands the phenotypic spectrum of TPM3-related disease and provides insights into the pathophysiological mechanisms of the actin-tropomyosin (显示 TPM2 抗体) complex

  5. Western blot showed phosphorylation of ALK, ERK1/2, and STAT3 (显示 STAT3 抗体) in cells transfected with TPM3-ALK. Coiled-coil structure of TPM3 contributes to the transforming ability of the TPM3-ALK fusion protein, and longer TPM3 region leads to higher dimer formation.

  6. Patients with TPM2 (显示 TPM2 抗体) mutations tended to present with milder symptoms than those with TPM3 mutations, DA being present only in the TPM2 (显示 TPM2 抗体) group.

  7. in a cohort of 94 patients with congenital myopathy, 2 related female patients and 2 sporadic male patients were found to carry mutations in TPM2 (显示 TPM2 抗体) and TPM3 genes respectively; clinical presentation and muscle morphological findings differed in the patients

  8. DATA show that tropomyosin 3 protein (TPM3) plays a critical role in the progression of gliomas.

  9. study reports on a three-generation family with cap myopathy caused by a novel heterozygous mutation in TPM3

  10. In addition to CLIC1 (显示 CLIC1 抗体) and TPM1 (显示 TPM1 抗体), which were the proteins initially discovered in a xenograft mouse model, CLIC4 (显示 CLIC4 抗体), TPM2 (显示 TPM2 抗体), TPM3, and TPM4 (显示 TPM4 抗体) were present in ovarian cancer patient sera at significantly elevated levels compared with controls.

Mouse (Murine) Tropomyosin 3 (TPM3) interaction partners

  1. Tpm3 plays crucial roles in maintaining cortical actin integrity and asymmetric cell division during oocyte maturation, and that dynamic regulation of cortical actin by Tpm3 is critical to ensure proper polar body protrusion.

  2. TMBr-3 and TM5NM1 modestly affected actin assembly kinetics, in an opposite manner.

  3. Tropomyosin (显示 TPM2 抗体) regulates cell migration during skin wound healing.

  4. Data conclude that exon 9d-containing isoforms are not essential for survival of neuronal cells and that isoform choice from the gamma-Tm gene is flexible in the brain

  5. Reduced expression of Tpm3, sarcomere genes and Lrtm1 in the diaphragm of mice with diaphragmatic defects.

  6. Tropomyosin 3 expression leads to hypercontractility and attenuates myofilament length-dependent Ca(2 (显示 CA2 抗体)+) activation.

  7. tropomyosin (显示 TPM2 抗体) isoforms regulate neuronal size and shape

  8. results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation-contraction coupling in skeletal muscle

TPM3 抗原简介


This gene encodes a member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. In muscle cells, they regulate muscle contraction by controlling the binding of myosin heads to the actin filament. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with anti-Tropomyosin 3 (TPM3) 抗体

  • tropomyosin 3 (TPM3) 抗体
  • tropomyosin 3 (tpm3) 抗体
  • tropomyosin 3, gamma (Tpm3) 抗体
  • tropomyosin 3 (Tpm3) 抗体
  • tropomyosin 3 S homeolog (tpm3.S) 抗体
  • tropomyosin alpha-3 chain (LOC100620599) 抗体
  • CAPM1 抗体
  • cb674 抗体
  • CFTD 抗体
  • fa17b11 抗体
  • fb83b01 抗体
  • fk41e01 抗体
  • gamma-TM 抗体
  • hm:zeh0298 抗体
  • hscp30 抗体
  • hTM30nm 抗体
  • hTMnm 抗体
  • NEM1 抗体
  • OK/SW-cl.5 抗体
  • TM-5 抗体
  • tm3 抗体
  • TM5 抗体
  • Tm5NM 抗体
  • TM30 抗体
  • TM30nm 抗体
  • Tpm-5 抗体
  • tpm3 抗体
  • tpm3.L 抗体
  • Tpm5 抗体
  • TPMsk3 抗体
  • TRK 抗体
  • Trop-5 抗体
  • wu:fa17b11 抗体
  • wu:fb83b01 抗体
  • wu:fk41e01 抗体
  • zeh0298 抗体
  • zgc:77592 抗体

Protein level used designations for anti-Tropomyosin 3 (TPM3) 抗体

alpha-tropomyosin, slow skeletal , cytoskeletal tropomyosin TM30 , heat-stable cytoskeletal protein 30 kDa , tropomyosin alpha-3 chain , tropomyosin gamma , tropomyosin-5 , gamma-tropomyosin , tropomyosin-3 , tropomyosin 3 , skalphaTM.2 , tropomyosin 5 , nonmuscle tropomyosin 5 , tropomyosin 3, gamma , tropomyosin non-muscle , tropomyosin 3 L homeolog , tropomyosin 3 S homeolog , Gamma-tropomyosin , Tropomyosin-3 , min alpha-trop

7170 Homo sapiens
373076 Danio rerio
414388 Sus scrofa
458000 Pan troglodytes
480137 Canis lupus familiaris
497019 Bos taurus
100174017 Pongo abelii
59069 Mus musculus
117557 Rattus norvegicus
100728267 Cavia porcellus
399420 Xenopus laevis
100620599 Sus scrofa
101108973 Ovis aries musimon
770103 Gallus gallus
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