anti-Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) 抗体

TRPM5 encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. 再加上,我们可以发TRPM5 蛋白 (6)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TRPM5 29850 Q9NZQ8
TRPM5 56843 Q9JJH7
TRPM5 365391  
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Showing 10 out of 58 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-TRPM5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  HepG2 cell lysate Immunohistochemistry with Pancreas tissue at an antibody concentration of 5µg/ml using anti-TRPM5 antibody (ARP35242_P050) 100 μL 2至3个工作日
$319.00
详细
豚鼠 非结合性 IHC, IHC (p), WB Anti-TRPM5 antibody IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958402 concentration 5 ug/ml. Anti-TRPM5 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other f ... 100 μL 11至14个工作日
$727.83
详细
Cow 非结合性 IHC, IHC (p), WB 100 μL 11至14个工作日
$507.83
详细
非结合性 IHC, WB IHC on paraffin sections of human small intestine tissue. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin. IHC on paraffin sections of human small intestine tissue. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1: 1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin. 100 μL 7至8个工作日
$454.67
详细
非结合性 IHC (p), WB TRPM5 was detected in paraffin-embedded sections of rat testis tissues using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method TRPM5 was detected in paraffin-embedded sections of mouse brain tissues using rabbit anti- TRPM5 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method 100 μg 4至6个工作日
$280.00
详细
非结合性 ELISA, WB 100 μL 2至3个工作日
$446.88
详细
非结合性 IHC, ELISA, WB 100 μL 2至3个工作日
$446.88
详细
非结合性 IHC, WB TRPM5 antibody was used for immunohistochemistry at a concentration of 4-8 ug/ml to stain Epithelial cells of intestinal villus (arrows) in Human Intestine. Magnification is at 400X TRPM5 antibody used at 1.25 ug/ml to detect target protein. 100 μg 9至11个工作日
$369.29
详细
非结合性 WB TRPM5 antibody used at 0.5 ug/ml to detect target protein. 50 μg 9至11个工作日
$483.57
详细
非结合性 WB Western blot analysis of extracts of various cell lines, using TRPM5 antibody (ABIN5999108) at 1:3000 dilution. 100 μL 11至18个工作日
$426.40
详细

更多抗TRPM5的相互作用对抗体

Human Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) interaction partners

  1. genetic association studies in populations in Northern Europe, Maghreb, and Sri Lanka: Data suggest that SNPs in TAS2R50 (rs1376251), TRPM5 (rs800345), and TAS2R16 (rs860170) are associated with cultural food preferences; TAS2R16 (rs860170) strongly differentiates populations and is associated to salicin bitterness perception. (TAS2R = taste receptor type 2)

  2. Our results suggest roles of TRPM3 and TRPM5 gene variants in the susceptibility to or clinical expression of Systemic sclerosis

  3. The PKC-dependent effect of GLP-1 on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 and TRPM5 channels by mobilization of intracellular Ca(2+) from thapsigargin-sensitive Ca(2+) stores

  4. In a Turkish population, genetic polymorphism in TRPM5 genes modify individual susceptibility to metabolic syndrome.

  5. TRPM5-mediated Na(+) entry to promote Ca(2+) uptake via an NCX to trigger MUC5AC secretion

  6. TrpM5 expression was similar throughout the olfactory glomeruli.

  7. The TRPM5 gene rs34551253 (Ala456Thr) polymorphism may be associated with increased risk of developing primary open angle glaucoma in the Turkish population.

  8. AZIN1 rs2679757 and TRPM5 rs886277 are associated with the risk of HBV-related liver cirrhosis in Chinese.

  9. extracellular Zn(2+) inhibits TRPM5 channels, and the residues in the outer pore loop of TRPM5 are critically involved in the inhibition.

  10. common TRPM5 variants are likely to be associated with prediabetic phenotypes; and this may in turn contribute to the development of type 2 diabetes mellitus

  11. results suggest TRPM5 may play a role in upregulating endogenous expression of TRPA1, that TRPA1 activation may be an additional trigger for co-expressed calcium-dependent ion channels such as TRPM5, and that TRPM5 may amplify responses to TRPA1 ligands

  12. TRPM5 gene is imprinted, with preferential expression from the paternal allele.

  13. TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i

  14. regulation of TRPM5 by Ca2+ mediates sensory activation in the taste system

  15. data show that extracellular acidification acts through specific residues on transient receptor potential cation channel, subfamily M(TRPM5) to block conduction through two distinct but related mechanisms

  16. understanding the structural basis for TRPM5 function will ultimately allow the design of pharmaceuticals to enhance or interfere with taste sensations--{REVIEW}

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5) interaction partners

  1. Both TRPM4 and TRPM5 are required for normal responses to bitter, sweet, and umami stimuli.

  2. This physiological and behavioral results indicate that TRPM5-MCs play a protective role in maintaining the olfactory function of the mammalian main olfactory epithelium.

  3. conclude that nAChR subunits are expressed in Trpm5-positive TRCs and their expression levels are differentially altered by chronic oral exposure to nicotine and ethanol

  4. propose that Skn-1a/Pou2f3 is the master regulator for the generation of the Trpm5-expressing microvillous cells in multiple tissues

  5. This study demonstrate that Trpm5 is transiently expressed in a subpopulation of mature OSNs in the embryonic olfactory epithelium, indicating that Trpm5 channels could play a specific role in utero during a narrow developmental time window.

  6. The PKC-dependent effect of GLP-1 on membrane potential and electrical activity was mediated by activation of Na(+)-permeable TRPM4 and TRPM5 channels by mobilization of intracellular Ca(2+) from thapsigargin-sensitive Ca(2+) stores

  7. The present findings confirm and extend our recent findings that Trpm5 KO mice express significant preferences for 8% glucose and galactose.

  8. Skn-1a is expressed in a minority of Mash1-positive olfactory progenitor cells and a majority of Trpm5-expressing microvillous cells in the main olfactory epithelium.

  9. The Trpm5 (but not T1r3) signaling is essential for starch preference, Trpm5 KO mice can learn to prefer starch based on its postoral effects.

  10. This study show that olfactory sensory neurons expressing TRPM5 respond to pheromones, but not to regular odors through the opening of CNG channels leading to Ca2+ gating of TRPM5

  11. Evidence suggests that TRPM5 plays a role in mediating transduction for putative pheromones under conditions of reduced chemosensory input.

  12. The results suggest that pharmacological or genetic alteration of TRPM5 activity modulates the benzamil-insensitive NaCl chorda tympani response and its modulation by TRPV1 agonists.

  13. The findings of this study indicated that T1r3 and Trpm5 play critical roles in carbohydrate-induced dietary obesity.

  14. There may be a TRPM5-independent transduction pathway for detecting the taste of sweetening substances.

  15. some amygdalopetal mitral cells extended dendrites to non-TRPM5-GFP glomeruli and vice versa, suggesting that, although significant overlapping glomerular innervation is observed between these two features, it is not absolute

  16. The prototypical long-chain free fatty acid stimulus, linoleic acid, depolarizes tumor cells in vitro via activation of TRPM5.

  17. FXYD6, a Na,K-ATPase regulator, is expressed in type II taste cells. Fxyd6 is coexpressed with transient receptor potential cation channel, subfamily M, member 5 (Trpm5), a critical component of the taste signal transduction pathways.

  18. Together, these studies show that TRPM5 channels play an essential role in fatty acid transduction in mouse taste cells

  19. discussion of data from various lines of investigation on the role of TRPM4 and TRPM5 in glucose-stimulated insulin secretion in pancreatic islets

  20. membrane voltage initiated by TRPM5 channels is required for ATP secretion during taste reception

TRPM5 抗原简介

蛋白简介

This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

Gene names and symbols associated with TRPM5

  • transient receptor potential cation channel subfamily M member 5 (TRPM5) 抗体
  • transient receptor potential cation channel, subfamily M, member 5 (Trpm5) 抗体
  • transient receptor potential cation channel, subfamily M, member 5 (trpm5) 抗体
  • 9430099A16Rik 抗体
  • LTrpC-5 抗体
  • Ltrpc5 抗体
  • Mtr1 抗体

Protein level used designations for TRPM5

transient receptor potential cation channel, subfamily M, member 5 , transient receptor potential cation channel subfamily M member 5-like , LTrpC-5 , MLSN1 and TRP-related , MLSN1- and TRP-related gene 1 protein , long transient receptor potential channel 5 , transient receptor potential cation channel subfamily M member 5 , long transient receptor potential-related channel 5

GENE ID SPECIES
100299596 Bos taurus
100457245 Pongo abelii
100466736 Ailuropoda melanoleuca
100533558 Sus scrofa
466320 Pan troglodytes
705070 Macaca mulatta
29850 Homo sapiens
483668 Canis lupus familiaris
56843 Mus musculus
557722 Danio rerio
365391 Rattus norvegicus
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