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TRPM5 抗体

TRPM5 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1386901
发货至: 中国
  • 抗原 See all TRPM5 抗体
    TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 22
    克隆类型
    • 22
    多克隆
    标记
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    This TRPM5 antibody is un-conjugated
    应用范围
    • 22
    • 12
    • 6
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human TRPM5
    亚型
    IgG
    Top Product
    Discover our top product TRPM5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))
    别名
    TRPM5 (TRPM5 产品)
    别名
    LTRPC5 antibody, MTR1 antibody, 9430099A16Rik antibody, LTrpC-5 antibody, Ltrpc5 antibody, Mtr1 antibody, transient receptor potential cation channel subfamily M member 5 antibody, transient receptor potential cation channel, subfamily M, member 5 antibody, TRPM5 antibody, Trpm5 antibody, trpm5 antibody
    背景

    Synonyms: MLSN1 and TRP related gene 1, MLSN1 and TRP related gene 1 protein, MLSN1 and TRP-related, MLSN1- and TRP-related gene 1 protein, MTR1, Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5 , Transient receptor potential cation channel subfamily M member 5, Transient receptor potential cation channel, subfamily M, member 5, Trpm5, TRPM5 transient receptor potential cation channel, subfamily M, member 5, TRPM5_HUMAN, 9430099A16Rik, Long transient receptor potential channel 5, LTrpC-5, LTrpC5.

    Background: Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

    基因ID
    29850
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