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TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. 再加上，我们可以发Thymic Stromal Lymphopoietin 抗体 (206) 和 Thymic Stromal Lymphopoietin 蛋白 (47)和数多这个蛋白质的别的产品。
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Human TSLP ELISA Kit for Sandwich ELISA - ABIN416956
Kouzaki, Matsumoto, Kato, Tojima, Shimizu, Shimizu: Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016
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Human TSLP ELISA Kit for Sandwich ELISA - ABIN625366
Chauhan, Singh, Agarwal, Paul: Correlation of TSLP, IL-33, and CD4 + CD25 + FOXP3 + T regulatory (Treg) in pediatric asthma. in The Journal of asthma : official journal of the Association for the Care of Asthma 2015
Human TSLP ELISA Kit for Sandwich ELISA - ABIN366622
Aktulay, Engin-Ustun, Ozkan, Demirtas, Yenicesu, Eyi, Mollamahmutoglu: Relationship between meconium staining and thymic stromal lymphopoietin. in European review for medical and pharmacological sciences 2014
production increased at skin sites of ovalbumin (显示 OVA ELISA试剂盒) sensitization
Sera of patients with infantile eosinophilic gastroenteritis showed a specific increase in both thymic stromal lymphopoietin and IL-33 (显示 IL33 ELISA试剂盒) levels.
short and long thymic stromal lymphopoietin isoforms have roles in house dust mite-induced asthmatic airway epithelial barrier disruption
DeltaNp73 was abundantly expressed in the atopic dermatitis epidermis and increased the release of TSLP via NF-kappaB (显示 NFKB1 ELISA试剂盒) activation.
this study shows that long form of thymic stromal lymphopoietin of keratinocytes is induced by protein allergens
we found that activation of the protease-activated receptor 1 (PAR1 (显示 F2R ELISA试剂盒)) induced secretion of TSLP by the corneal stromal cells... we proposed that TSLP might function as the link between increased protease activity and inflammatory responses or itch sensation in the corneas
TSLP-HOTAIR axis also plays a protective role in low-density lipoprotein (ox-LDL)-induced Endothelial cells' injury.
The aim of this study was to determine the influence of human rhinovirus on the genes involved in airway remodeling and to examine the impact of TSLP and contribution of oxidative stress on airway remodeling in the context of HRV infection.
TSLP-induced phosphorylation of l-plastin (显示 LCP1 ELISA试剂盒) is increased in atopic dermatitis and increases eosinophil migration.
a hit expansion exercise yielded additional active compounds that could be amenable to further optimization, providing an opportunity to dissociate TSLP inhibition from other non-desired activities. This study illustrates the potential of phenotypic drug discovery to complement target based approaches by providing new chemistry and biology leads
findings suggest a role of TSLP in directly promoting Th2 cell effector function and support the notion of TSLP as a key driver of Th2
Thymic stromal lymphopoietin and IL-33 (显示 IL33 ELISA试剂盒) promote skin inflammation and vaccinia virus replication in a mouse model of atopic dermatitis.
the pathological mechanisms of particulate matter PM2.5 may be associated with allergic/steroidresistant airway inflammation, Tcell helper (Th)1 (显示 TH1L ELISA试剂盒)/Th2 cytokine production and upregulation of TSLP expression in a murine model of allergic and steroid-resistant asthma.
These findings suggest miR (显示 MLXIP ELISA试剂盒)-19b reduces airway remodeling, airway inflammation, and degree of oxidative stress by inhibiting Stat3 (显示 STAT3 ELISA试剂盒) signaling through TSLP downregulation in a mouse asthma model.
Results suggest combinatorial mechanisms involved in the tissue-selective regulation of thymic stromal lymphopoietin (TSLP) transcription in epidermal keratinocytes and intestinal epithelial cell(s) (IEC).
these results suggest that TSLP-TSLPR (显示 CRLF2 ELISA试剂盒) signaling is pivotal in the induction of nasal respiratory immunity against pathogenic pneumococcal infection
blockading the JAK (显示 JAK3 ELISA试剂盒)/STAT (显示 STAT1 ELISA试剂盒) pathway restrains inflammatory Th2 cell response induced by TSLP-DCs in allergic rhinitis.
study concludes that IL-33 (显示 IL33 ELISA试剂盒) and TSLP are required for epithelial cell IL-25 (显示 IL25 ELISA试剂盒) expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection
TSLP plays a role in dysfunction of airway epithelial adherens junctions E-cadherin (显示 CDH1 ELISA试剂盒) in house dust mite (HDM (显示 HDAC3 ELISA试剂盒))-induced asthma. Mice treated with an anti-TSLP mAb ameliorated airway inflammation, the decreasing and aberrant distribution of E-cadherin (显示 CDH1 ELISA试剂盒) and beta-catenin (显示 CTNNB1 ELISA试剂盒) as well as phosphorylation(p)-AKT (显示 AKT1 ELISA试剂盒) induced by HDM (显示 HDAC3 ELISA试剂盒). In vitro, HDM (显示 HDAC3 ELISA试剂盒) increased the expression of TSLP and E-cadherin (显示 CDH1 ELISA试剂盒) dysfunction by PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling pathway.
this study shows that TSLP is a key target of Mi-2beta (显示 CHD4 ELISA试剂盒) in keratinocytes, and that loss of TSLP signaling in regulatory T cells prevents their activation
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
thymic stromal lymphopoietin
, thymic stromal lymphopoetin
, thymic stroma-derived lymphopoietin