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TSLP encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. 再加上，我们可以发Thymic Stromal Lymphopoietin 抗体 (192) 和 Thymic Stromal Lymphopoietin 蛋白 (41)和数多这个蛋白质的别的产品。
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Human TSLP ELISA Kit for Sandwich ELISA - ABIN416956
Kouzaki, Matsumoto, Kato, Tojima, Shimizu, Shimizu: Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2016
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Human TSLP ELISA Kit for Sandwich ELISA - ABIN366622
Aktulay, Engin-Ustun, Ozkan, Demirtas, Yenicesu, Eyi, Mollamahmutoglu: Relationship between meconium staining and thymic stromal lymphopoietin. in European review for medical and pharmacological sciences 2014
Human TSLP ELISA Kit for Sandwich ELISA - ABIN625366
Chauhan, Singh, Agarwal, Paul: Correlation of TSLP, IL-33, and CD4 + CD25 + FOXP3 + T regulatory (Treg) in pediatric asthma. in The Journal of asthma : official journal of the Association for the Care of Asthma 2015
this study shows that long form of thymic stromal lymphopoietin of keratinocytes is induced by protein allergens
we found that activation of the protease-activated receptor 1 (PAR1 (显示 F2R ELISA试剂盒)) induced secretion of TSLP by the corneal stromal cells... we proposed that TSLP might function as the link between increased protease activity and inflammatory responses or itch sensation in the corneas
TSLP-HOTAIR axis also plays a protective role in low-density lipoprotein (ox-LDL)-induced Endothelial cells' injury.
The aim of this study was to determine the influence of human rhinovirus on the genes involved in airway remodeling and to examine the impact of TSLP and contribution of oxidative stress on airway remodeling in the context of HRV infection.
TSLP-induced phosphorylation of l-plastin (显示 LCP1 ELISA试剂盒) is increased in atopic dermatitis and increases eosinophil migration.
a hit expansion exercise yielded additional active compounds that could be amenable to further optimization, providing an opportunity to dissociate TSLP inhibition from other non-desired activities. This study illustrates the potential of phenotypic drug discovery to complement target based approaches by providing new chemistry and biology leads
study found that among patients with atopic dermatitis (AD), common FLG (显示 FGFR1 ELISA试剂盒) null mutations are associated with earlier AD onset in a dose-dependent manner, whereas TSLP rs1898671 appears unrelated to the timing of AD onset
lactobacilli from the omnivorous group and all bifidobacteria significantly down-regulated IL-8 (显示 IL8 ELISA试剂盒). Notably, both genera also lowered the TSLP expression in stimulated Caco-2 cells, regardless of the diet regimen.
this review focuses on recent advances on the effects of TSLP on obstetrical and gynecological diseases, including pregnancy failure, endometriosis, and cervical cancer
The increase in TSLP and TNF-alpha (显示 TNF ELISA试剂盒) level observed in IS fluid was found to correlate with disease severity. The increased TSLP production from asthma sputum cells was abrogated by the addition of rIL-37. Regulation of TSLP pathway may be a therapeutic approach for asthma.
These findings suggest miR (显示 MLXIP ELISA试剂盒)-19b reduces airway remodeling, airway inflammation, and degree of oxidative stress by inhibiting Stat3 (显示 STAT3 ELISA试剂盒) signaling through TSLP downregulation in a mouse asthma model.
Results suggest combinatorial mechanisms involved in the tissue-selective regulation of thymic stromal lymphopoietin (TSLP) transcription in epidermal keratinocytes and intestinal epithelial cell(s) (IEC).
these results suggest that TSLP-TSLPR (显示 CRLF2 ELISA试剂盒) signaling is pivotal in the induction of nasal respiratory immunity against pathogenic pneumococcal infection
blockading the JAK (显示 JAK3 ELISA试剂盒)/STAT (显示 STAT1 ELISA试剂盒) pathway restrains inflammatory Th2 cell response induced by TSLP-DCs in allergic rhinitis.
study concludes that IL-33 (显示 IL33 ELISA试剂盒) and TSLP are required for epithelial cell IL-25 (显示 IL25 ELISA试剂盒) expression, mucous metaplasia, and ILC2 expansion following early-life rhinovirus infection
TSLP plays a role in dysfunction of airway epithelial adherens junctions E-cadherin (显示 CDH1 ELISA试剂盒) in house dust mite (HDM (显示 HDAC3 ELISA试剂盒))-induced asthma. Mice treated with an anti-TSLP mAb ameliorated airway inflammation, the decreasing and aberrant distribution of E-cadherin (显示 CDH1 ELISA试剂盒) and beta-catenin (显示 CTNNB1 ELISA试剂盒) as well as phosphorylation(p)-AKT (显示 AKT1 ELISA试剂盒) induced by HDM (显示 HDAC3 ELISA试剂盒). In vitro, HDM (显示 HDAC3 ELISA试剂盒) increased the expression of TSLP and E-cadherin (显示 CDH1 ELISA试剂盒) dysfunction by PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling pathway.
this study shows that TSLP is a key target of Mi-2beta (显示 CHD4 ELISA试剂盒) in keratinocytes, and that loss of TSLP signaling in regulatory T cells prevents their activation
These data demonstrate that multiple pathogenic strains of RSV induce IL-13 (显示 IL13 ELISA试剂盒)-producing group 2 innate lymphoid cell proliferation and activation through a TSLP-dependent mechanism in a murine model and suggest the potential therapeutic targeting of TSLP during severe RSV infection.
the effects of TSLP on myeloid cells are crucial in reducing the multiple organ failure that is associated with systemic inflammation.
The inflammatory phenotype in barrier-defective skin is shaped by counterregulation between the TSLP/type 2 and IL-23 (显示 IL23A ELISA试剂盒)/type 17 axes.
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
thymic stromal lymphopoietin
, thymic stromal lymphopoetin
, thymic stroma-derived lymphopoietin