anti-Tafazzin (TAZ) 抗体

TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. 再加上,我们可以发TAZ 蛋白 (13)TAZ 试剂盒 (7)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
TAZ 6901 Q16635
TAZ 66826  
TAZ 363521  
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antibodies-online.cn销售最多的anti-TAZ 抗体

Showing 10 out of 167 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB Lanes: Lane 1:241 µg mouse cardiac mitochondria lysate Lane 2: 041 µg mouse cardiac mitochondria lysate  Lane 3: 041 µg mouse cardiac mitochondria lysate   ane 4: 041 µg mouse cardiac mitochondria lysate Primary Antibody Dilution: 1:000Secondary Antibody: Goat anti-rabbit-HRP Secondary Antibody Dilution: 1:0500  Gene Name: TAZ An Submitted by: Corey Powers, Cincinati Children's Hospital Medical Center 100 μL Log in to see 2至3个工作日
$289.00
详细
山羊 非结合性 ELISA, WB ABIN185489 (0.3µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
$429.84
详细
非结合性 WB Western blot analysis of TAZ expression in MCF7 (A), NIH3T3 (B), H9C2 (C), human heart (D) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 FACS, IHC (p), WB Western blot analysis of TAZ Antibody (N-term) (ABIN652751) in MDA-MB231, NCI-H460 cell line lysates (35 µg/lane). TAZ (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAZ Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
$385.00
详细
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged TAZ is approximately 3ng/ml as a capture antibody. 100 μg Log in to see 8至11个工作日
$527.50
详细
小鼠 非结合性 ELISA, IF Immunofluorescence of monoclonal antibody to TAZ on HeLa cell . [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged TAZ is approximately 10ng/ml as a capture antibody. 100 μg Log in to see 8至11个工作日
$527.50
详细
非结合性 IHC (p) IHC-P Image TAZ antibody [C2C3], C-term detects TAZ protein at cytoplasm on human placenta by immunohistochemical analysis. Sample: Paraffin-embedded placenta. TAZ antibody [C2C3], C-term , dilution: 1:100. 100 μL Log in to see 3至4个工作日
$466.18
详细
非结合性 ICC, IHC, WB Western Blot; Sample: Human HepG2 cell lysate; Primary Ab: 2µg/ml Rabbit Anti-Human TAZ Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13至16个工作日
$350.00
详细
非结合性 ELISA, IHC, IHC (p) Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-TAZ antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μL Log in to see 11至14个工作日
$484.00
详细
Bat 山羊 非结合性 ELISA, WB 100 μg Log in to see 11至14个工作日
$610.50
详细

引用最多的anti-TAZ 抗体

  1. Human Monoclonal TAZ Primary Antibody for ELISA, WB - ABIN520708 : Raghunathan, Morgan, Dreier, Reilly, Thomasy, Wood, Ly, Tuyen, Hughbanks, Murphy, Russell: Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ. in Investigative ophthalmology & visual science 2013 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal TAZ Primary Antibody for IF (p), IHC (p) - ABIN1713913 : Sun, Chen, Shi, Qi, Zhao, Zhang: Prognostic impact of TAZ and ?-catenin expression in adenocarcinoma of the esophagogastric junction. in Diagnostic pathology 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal TAZ Primary Antibody for ELISA, WB - ABIN269827 : Brandner, Mick, Frazier, Taylor, Meisinger, Rehling: Taz1, an outer mitochondrial membrane protein, affects stability and assembly of inner membrane protein complexes: implications for Barth Syndrome. in Molecular biology of the cell 2005 (PubMed)

更多抗TAZ的相互作用对抗体

Zebrafish Tafazzin (TAZ) interaction partners

  1. Disrupted gene function in yap1(-/-); taz(+/-) embryos did not disturb liver bud formation, but instead impaired cell proliferation in liver and movement of the neighboring lateral plate mesoderm (LPM). Overexpression of wild type yap1 or taz could rescue the defective liver phenotypes in yap1(-/-); taz(+/-) embryos.

  2. During vascular regression, Yap/Taz is activated by blood circulation in the endothelial cells. This leads to induction of Ctgf and actin polymerization. Interference with Yap/Taz activation decreased Ctgf production, which decreased actin polymerization and vascular regression.

  3. knockdown phenotype demonstrates that abnormal cardiac development, with a linear, nonlooped heart, and hypomorphic tail and eye development proves that tafazzin is essential for overall zebrafish development, especially of the heart.

Human Tafazzin (TAZ) interaction partners

  1. TAZ(Q233del) plays a major role in regulating malignancy of cancer cells by hijacking Hippo pathway.

  2. Study characterized structural and metabolic adaptations in Barth syndrome patients primary skin fibroblasts and provided novel insights into the molecular details of supercomplex destabilization, aberrant cristae morphology and metabolic changes resulting from TAZ mutations.

  3. We report a novel TAZ gene mutation in male and female siblings with left ventricular noncompaction and hypotonia. Additionally, the brother presented an intermittent neutropenia and increased urinary levels of 3-methylglutaconic and 3-methylglutaric acid. The molecular genetic testing showed that both siblings carry the mutation: c.253insC, p.(Arg85Profs*54) in exon 3 of the TAZ gene. Normal karyotype female.

  4. Report left ventricular non-compaction associated with Barth Syndrome due to triple mutations in TAZ, DTNA, and SDHA genes in multiple members of one family.

  5. TAZ overexpression is associated with poor response to chemotherapy in chronic myeloid leukemia.

  6. High TAZ expression is associated with cisplatin-resistance in gastric cancer.

  7. This is the first report of systematic mutation screening of TAZ in a large cohort of pediatric patients with primary cardiomyopathy using the NGS approach. TAZ mutations were found in 4/114 (3.5%) male patients with primary cardiomyopathy. Our findings indicate that the inclusion of TAZ gene testing in cardiomyopathy genetic testing panels may contribute to the early diagnosis of BTHS.

  8. TAZ mutation-confirmed diagnosis of Barth syndrome (BTHS) was available for 39/42 of the participants. Of 39 patients, 13 have a missense mutation, 6 have a nonsense mutation, 8 have a splicing mutation, 6 have a small out-of-frame insertion or deletion, 2 have a small in-frame insertion, and 4 have a large deletion encompassing several exons

  9. TAZ is overexpressed in cervical cancer and may promote tumorigenicity of cervical cancer cells and inhibit apoptosis.

  10. TAZ mutation is associated with Barth syndrome.

  11. Molecular analysis of at risk female family members identified the patient's sister and mother as heterozygous carriers. Apparently harmless synonymous variants in the TAZ gene can damage gene expression. Such findings widen our knowledge of molecular heterogeneity in Barth syndrome.

  12. two novel and non-identical TAZ gene rearrangements were found in the offspring of a single female carrier of Barth syndrome.

  13. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  14. ability of CL-ND to elicit a physiological response was examined in an HL60 cell culture model of Barth Syndrome neutropenia. siRNA knockdown of the phospholipid transacylase, tafazzin (TAZ), induced apoptosis in these cells

  15. novel mutation in exon 1 of the TAZ gene and female mosaicism in three generations of a Polish family with Barth syndrome

  16. mitochondria-targeted antioxidant prevents cardiac dysfunction induced by tafazzin gene knockdown in cardiac myocytes

  17. Strong expression of TAZ protein seems to be related to rectal cancer development and RT response, it can be a predictive biomarker of distant recurrence in patients with preoperative RT.

  18. Three novel hemizygous mutations in the TAZ gene were found (c.584G>T; c.109+6T>C; c.86G>A). We conclude that Barth syndrome should be included in differential diagnosis of cardiomyopathy in childhood.

  19. Results show that in both healthy controls and in Barth syndrome patients, a greater variety of alternatively spliced forms than previously described was found. It includes a sizeable proportion of minor splice variants besides the four dominant isoforms.

  20. data suggest that genes other than G4.5 are responsible for the familial form of noncompaction of the ventricular myocardium

Mouse (Murine) Tafazzin (TAZ) interaction partners

  1. results suggest that plasmenylcholine, abundant in linoleoyl species, is important in remodeling CL in the heart. Tafazzin deficiency thus has a major impact on the cardiac plasmenylcholine level and thereby its functions.

  2. The impact of endurance training on the cardiac and skeletal muscle phenotype in young TAZ knock-down mice.

  3. impaired Taz-function with onset at adult age does not enhance susceptibility to ischemia-reperfusion injury.

  4. A novel role for Taz in helping to maintain genome integrity in spermatocyte meiosis and facilitating germ cell differentiation.

  5. Tafazzin deficiency in mouse embryonic fibroblasts also led to impaired oxidative phosphorylation and severe oxidative stress

  6. TAZ mutation is necessary and sufficient for the phenotype of sparse and irregular sarcomeres and weak myocaridal contraction foudn in Barth syndrome.

  7. Tafazzin knockdown mice provide a mammalian model system for Barth syndrome in which the pathophysiological relationships between altered content of mitochondrial phospholipids, ultrastructural abnormalities, myocardial and mitochondrial dysfunction

  8. The data suggest that tafazzin deficiency affects cardiolipin in all mitochondria, but significant alterations of the ultrastructure, such as remodeling and aggregation of inner membranes, will only occur after specific differentiation.

TAZ 抗原简介

蛋白简介

This gene encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced\; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.

Gene names and symbols associated with anti-Tafazzin (TAZ) 抗体

  • tafazzin (TAZ) 抗体
  • tafazzin (taz) 抗体
  • tafazzin L homeolog (taz.L) 抗体
  • tafazzin homolog (LOC550948) 抗体
  • tafazzin (AFUA_2G13960) 抗体
  • tafazzin (AOR_1_318014) 抗体
  • tafazzin (Tsp_06712) 抗体
  • tafazzin (Taz) 抗体
  • 5031411C02Rik 抗体
  • 9130012G04Rik 抗体
  • Afu2g13960 抗体
  • AW107266 抗体
  • AW552613 抗体
  • BTHS 抗体
  • CMD3A 抗体
  • EFE 抗体
  • EFE2 抗体
  • G4.5 抗体
  • GB11956 抗体
  • LVNCX 抗体
  • MGC54019 抗体
  • taz 抗体
  • Taz1 抗体
  • wu:fb39f12 抗体
  • zgc:91803 抗体

Protein level used designations for anti-Tafazzin (TAZ) 抗体

tafazzin , Tafazzin , protein G4.5 , Barth syndrome) , endocardial fibroelastosis 2 , tafazzin (cardiomyopathy, dilated 3A (X-linked) , tafazzin (cardiomyopathy, dilated 3A (X-linked); endocardial fibroelastosis 2; Barth syndrome)

GENE ID SPECIES
100446947 Pongo abelii
321965 Danio rerio
379259 Xenopus laevis
515177 Bos taurus
549220 Xenopus (Silurana) tropicalis
550948 Apis mellifera
3513201 Aspergillus fumigatus Af293
5993687 Aspergillus oryzae RIB40
10911739 Trichinella spiralis
100137265 Papio anubis
100196028 Salmo salar
100328759 Oryctolagus cuniculus
100528715 Ictalurus punctatus
6901 Homo sapiens
66826 Mus musculus
363521 Rattus norvegicus
612975 Canis lupus familiaris
449590 Pan troglodytes
574297 Macaca mulatta
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