Component of the THO subcomplex of the TREX complex.
THO Complex 7 Homolog (Drosophila) (THOC7) 抗原简介
Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between ALYREF/THOC4 and the THO complex (By similarity).
Gene names and symbols associated with THOC7
THO complex 7 (Thoc7) 抗体
THO complex 7 (THOC7) 抗体
Protein level used designations for THOC7
THO complex subunit 7 homolog
, NIF3L1-binding protein 1
, Ngg1 interacting factor 3 like 1 binding protein 1
, functional spliceosome-associated protein 24
, ngg1-interacting factor 3-like protein 1-binding protein 1