anti-Spinster Homolog 2 (Drosophila) (SPNS2) 抗体

Sphingolipid transporter required for migration of myocardial precursors. 再加上,我们可以发SPNS2 蛋白 (3)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
SPNS2 216892 Q91VM4
SPNS2 100270678  
SPNS2 124976 Q8IVW8
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产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 WB 100 μL 2至3个工作日
$319.00
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Bat 非结合性 IHC, IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) Anti-SPNS2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other form ... 100 μL 11至14个工作日
$727.83
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非结合性 ELISA, WB   100 μg 6至7个工作日
$525.06
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非结合性 WB   100 μL 11至14个工作日
$551.83
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非结合性 ELISA, WB   200 μL 11至16个工作日
$658.43
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Biotin ELISA, WB   200 μL 11至14个工作日
$1,101.83
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APC ELISA, WB   200 μL 11至14个工作日
$1,101.83
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PE ELISA, WB   200 μL 11至14个工作日
$1,101.83
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FITC ELISA, WB   200 μL 11至14个工作日
$1,101.83
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Alkaline Phosphatase (AP) ELISA, WB   200 μL 11至14个工作日
$1,101.83
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更多抗SPNS2的相互作用对抗体

Zebrafish Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. Spinster 2 (SPNS2) was shown to act as a mediator of intracellular sphingosine-1-phosphate (S1P) release and play an important role in the regulation of S1P [Review].

  2. Toh is required for signaling by S1P(2)and is involved in the trafficking or cellular release of S1P.

  3. findings show that Spns2 in the yolk syncytial layer functions as a sphingosine-1-phosphate (S1P) transporter in S1P secretion, thereby regulating myocardial precursor migration

Mouse (Murine) Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. In summary, these results suggest that Spns2 promotes pro-inflammatory polarization of microglia and may play a crucial role in Alzheimer disease pathogenesis.

  2. SPNS2 is essential for proper postnatal retinal morphogenesis.

  3. genome-wide in vivo screen identifies novel host regulators of metastatic colonization, such as Spns2

  4. results point to a broad role for Spns2-mediated S1P transport in the initiation and development of adaptive immune related disorders

  5. Spns2 expression by endothelial cells is essential for secretion of lymph S1P, while Spns2 is dispensable for RBC secretion of plasma S1P.

  6. Spns2 is an S1P transporter in vivo that plays a role in regulation not only of blood S1P but also lymph node and lymph S1P levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization.

  7. SPNS2 is the first physiological S1P transporter in mammals and is a key determinant of lymphocyte egress from the thymus.

  8. The changes in lymphocyte subpopulations in mutant Spns2 mice closely mimick the phenotypes of partial sphingosine-1-phosphate (S1P) deficiency, impaired S1P-dependent lymphocyte trafficking, and depletion of circulating lymphocytes.

  9. Spns2 functions in endothelial cells to establish the S1P gradient required for T and B cells to egress from their respective primary lymphoid organs.

  10. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

Human Spinster Homolog 2 (Drosophila) (SPNS2) interaction partners

  1. Spinster 2 (SPNS2) was shown to act as a mediator of intracellular sphingosine-1-phosphate (S1P) release and play an important role in the regulation of S1P [Review].

  2. our data demonstrate that Spns2 and S1P have a crucial effect on proximal tubular epithelial cells by regulating an inflammatory process and a subsequent fibrotic reaction, and also by influencing other tubular transporters that are involved in the pathophysiology of inflammatory and fibrotic kidney diseases.

  3. Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development

  4. In both macrophage and epithelial cell types, Spns2 was also found localized to cytoplasm and the nucleus, in line with a predicted bipartile Nuclear Localization Signal at the position aa282 of the human Spns2 sequence

  5. A novel role for Spns2 and S1P1&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.

  6. Spns2 plays key roles in regulating the cellular functions in non-small cell lung cancer (NSCLC) cells

  7. mammals. These findings indicate that Spns2 is required for normal maintenance of the endocochlear potential and hence for normal auditory function, and support a role for S1P signalling in hearing.

  8. Spns2 is an S1P transporter in vivo that plays a role in regulation not only of blood S1P but also lymph node and lymph S1P levels and consequently influences lymphocyte trafficking and lymphatic vessel network organization.

  9. The sphingosine 1-phosphate transporter, SPNS2, functions as a transporter of the phosphorylated form of the immunomodulating agent FTY720.

SPNS2 抗原简介

蛋白简介

Sphingolipid transporter required for migration of myocardial precursors. Transports sphingosine 1-phosphate (S1P), a secreted lipid mediator that plays critical roles in cardiovascular, immunological, and neural development and function. Mediates the export of S1P from cells in the extraembryonic yolk syncytial layer (YSL), thereby regulating myocardial precursor migration.

Gene names and symbols associated with SPNS2

  • spinster homolog 2 (Drosophila) (SPNS2) 抗体
  • spinster homolog 2 (Drosophila) (spns2) 抗体
  • sphingolipid transporter 2 (SPNS2) 抗体
  • spinster homolog 2 (spns2) 抗体
  • spinster homolog 2 (Spns2) 抗体
  • sphingolipid transporter 2 (Spns2) 抗体
  • DKFZp459J1933 抗体
  • fi20h04 抗体
  • si:dkey-7b17.4 抗体
  • toh 抗体
  • wu:fi20h04 抗体

Protein level used designations for SPNS2

spinster homolog 2 (Drosophila) , protein spinster homolog 2 , two of hearts , protein two of hearts , mCG6652-like , spinster-like protein , spinster2

GENE ID SPECIES
417492 Gallus gallus
568117 Danio rerio
606858 Canis lupus familiaris
613889 Bos taurus
100072726 Equus caballus
100145187 Xenopus (Silurana) tropicalis
100172034 Pongo abelii
216892 Mus musculus
100270678 Rattus norvegicus
124976 Homo sapiens
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