The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown. [provided by RefSeq, Jul 2008].
Kim, Denli, Wright, Baul, Clemenson, Morcos, Zhao, Schafer, Gage, Kagalwala: "REST Regulates Non-Cell-Autonomous Neuronal Differentiation and Maturation of Neural Progenitor Cells via Secretogranin II." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 44, pp. 14872-84, (2015) (PubMed).
Aliases for SCG2 蛋白
secretogranin II L homeolog (scg2.L) 蛋白 secretogranin II (chromogranin C), b (scg2b) 蛋白 secretogranin II (scg2) 蛋白 secretogranin II (SCG2) 蛋白 Secretogranin-2 (scg2) 蛋白 secretogranin II (Scg2) 蛋白 Chcg 蛋白 CHGC 蛋白 Chgc 蛋白 DKFZp459O193 蛋白 EM66 蛋白 LOC397939 蛋白 MGC84703 蛋白 MGC145924 蛋白 scg2 蛋白 SCG2 蛋白 SCGG2 蛋白 SgII 蛋白 SN 蛋白 wu:fj34e01 蛋白 zgc:153925 蛋白