Sclerostin (SOST) ELISA试剂盒

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. 再加上,我们可以发Sclerostin 抗体 (128)Sclerostin 蛋白 (18)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
SOST 50964 Q9BQB4
SOST 74499 Q99P68
SOST 80722 Q99P67
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
$1,026.67
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小鼠 2.79 pg/mL 6.25 pg/mL - 400 pg/mL 96 Tests Log in to see 13至16个工作日
$606.32
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大鼠 32 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Log in to see 13至16个工作日
$640.00
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Cow 15.63 pg/mL   96 Tests Log in to see 15至18个工作日
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0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15至18个工作日
$707.14
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豚鼠 0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15至18个工作日
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0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15至18个工作日
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0.1 ng/mL 0.5-10 ng/mL   96 Tests Log in to see 15至18个工作日
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Pig
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绵羊
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引用最多的Sclerostin ELISA试剂盒

  1. Human Sclerostin ELISA Kit for Sandwich ELISA - ABIN457071 : Cidem, Usta, Karacan, Kucuk, Uludag, Gun: Effects of sex steroids on serum sclerostin levels during the menstrual cycle. in Gynecologic and obstetric investigation 2013 (PubMed)
    Show all 5 Pubmed References

  2. Human Sclerostin ELISA Kit for Sandwich ELISA - ABIN415155 : Brabnikova Maresova, Pavelka, Stepan: Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes. in Calcified tissue international 2013 (PubMed)
    Show all 3 Pubmed References

  3. Mouse (Murine) Sclerostin ELISA Kit for Sandwich ELISA - ABIN426039 : Yorgan, Peters, Jeschke, Benisch, Jakob, Amling, Schinke: The Anti-Osteoanabolic Function of Sclerostin Is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 (PubMed)
    Show all 2 Pubmed References

  4. Rat (Rattus) Sclerostin ELISA Kit for Sandwich ELISA - ABIN416496 : Kim, Lee, Jo, Song, Lim, Park, Bonewald, Kim: Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes. in Life sciences 2013 (PubMed)
    Show all 2 Pubmed References

  5. Rat (Rattus) Sclerostin ELISA Kit for Sandwich ELISA - ABIN585201 : Ferreira, Ferrari, Neves, Cavallari, Dominguez, Dos Reis, Graciolli, Oliveira, Liu, Sabbagh, Jorgetti, Schiavi, Moysés: Effects of dietary phosphate on adynamic bone disease in rats with chronic kidney disease--role of sclerostin? in PLoS ONE 2013 (PubMed)

适于 Sclerostin 相互作用对的更多 ELISA 试剂盒

Human Sclerostin (SOST) interaction partners

  1. Sclerostin increased after exercise in comparison to baseline (mean +/- SEM: 410 +/- 27 vs. 290 +/- 19 pg/mL; p < 0.001) corresponding to an increase of +44.3 +/-5.5%

  2. serum sclerostin levels correlated positively with carotid intima-media thickness and inversely with the augmentation index, a marker of arterial stiffness

  3. The difference of serum sclerostin levels in Ankylosing Spondylitis and Rheumatoid Arthritis patients was not significantly different from HC, indicating that the sclerostin may not associate with the development of Ankylosing Spondylitis and Rheumatoid Arthritis.

  4. SOST gene silencing promotes the proliferation, invasion, and migration, and inhibits apoptosis of osteosarcoma cells by activating Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) signaling pathway

  5. No difference was found in the serum sclerostin levels between the hyperthyroidism patients and healthy control.

  6. Positivity of RANKL (显示 TNFSF11 ELISA试剂盒) and anti-CCP2 yielded significant risk for progression with negativity for both as reference. No single nucleotide polymorphism encoding TNFSF11 (显示 TNFSF11 ELISA试剂盒) or SOST was associated with increased concentrations of the factors.

  7. Osterix (显示 SP7 ELISA试剂盒) and RUNX2 (显示 RUNX2 ELISA试剂盒) are transcriptional regulators of sclerostin in human bone

  8. Sclerostin But Not Dickkopf-1 (显示 DKK1 ELISA试剂盒) has roles in increasing prevalence of osteoporotic fracture and lower bone mineral density in postmenopausal Korean women

  9. An association was found between rs851054 of the SOST promoter and the fracture rate during childhood osteogenesis imperfecta (显示 COL1A2 ELISA试剂盒).

  10. High serum levels of sclerostin and Dkk-1 (显示 DKK1 ELISA试剂盒) are associated with acute ischaemic stroke

Mouse (Murine) Sclerostin (SOST) interaction partners

  1. These results show that osteocytes and/or osteoblasts secrete factors regulating beige (显示 LYST ELISA试剂盒) adipogenesis, at least in part, through the Wnt (显示 WNT2 ELISA试剂盒)-signaling inhibitor sclerostin.

  2. In vivo muCT analysis of cortical bone at age 1 and 3 months confirmed increased thickness in Sost-/-mice, but revealed no cortical abnormalities in single Gja1 (显示 GJA1 ELISA试剂盒)+/-or Sost+/-mice

  3. loss of BMP signaling specifically in osteocytes dramatically increases bone mass presumably through simultaneous inhibition of RANKL (显示 TNFSF11 ELISA试剂盒) and SOST, leading to osteoclast inhibition and Wnt (显示 WNT2 ELISA试剂盒) activation together.

  4. humanized Multiple Myeloma xenograft mouse model bearing human MM cells (NOD-SCID.CB17 male mice injected intravenously with 2.5 million of MM1 (显示 PFDN5 ELISA试剂盒).S-Luc-GFP cells) demonstrated significantly higher concentrations of mouse-derived sclerostin, suggesting a microenvironmental source of sclerostin.

  5. Protection From Glucocorticoid-Induced Osteoporosis by Anti-Catabolic Signaling in the Absence of Sost/Sclerostin

  6. Osteocyte-derived molecule sclerostin drives bone marrow adipogenesis.

  7. complete absence of sclerostin has only minor effects on chronic kidney disease-induced bone loss in mice.

  8. In mice, sclerostin deficiency hastened reparative dentinogenesis after pulp injury, suggesting that the inhibition of sclerostin may constitute a promising therapeutic strategy for improving the healing of damaged pulps.

  9. These data suggest that sclerostin plays an important role in the bone remodeling of tooth movement.

  10. Sclerostin inhibits angiotensin II-induced aortic aneurysm and atherosclerosis via wnt (显示 WNT2 ELISA试剂盒) signaling pathway inhibition.

Sclerostin (SOST) 抗原简介

Antigen Summary

Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.

Gene names and symbols associated with Sclerostin (SOST) ELISA试剂盒

  • sclerostin (LOC100313724) 抗体
  • sclerostin (SOST) 抗体
  • sclerostin (Sost) 抗体
  • 5430411E23Rik 抗体
  • CDD 抗体
  • LOC100313724 抗体
  • VBCH 抗体

Protein level used designations for Sclerostin (SOST) ELISA试剂盒

sclerostin , sclerosteosis

GENE ID SPECIES
100313724 Saccoglossus kowalevskii
50964 Homo sapiens
74499 Mus musculus
80722 Rattus norvegicus
490948 Canis lupus familiaris
100730713 Cavia porcellus
282880 Bos taurus
429784 Gallus gallus
101114123 Ovis aries
100513306 Sus scrofa
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