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Sclerostin ELISA 试剂盒

SOST 适用: 人 AA 24-213 Colorimetric Sandwich ELISA
产品编号 ABIN5510605
发货至: 中国
  • 抗原 See all Sclerostin (SOST) ELISA试剂盒
    Sclerostin (SOST)
    抗原表位
    AA 24-213
    适用
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: Q24-Y213
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all Sclerostin (SOST) ELISA试剂盒
    Sclerostin (SOST)
    别名
    SOST (SOST 产品)
    别名
    LOC100313724 ELISA Kit, CDD ELISA Kit, VBCH ELISA Kit, 5430411E23Rik ELISA Kit, sclerostin ELISA Kit, LOC100313724 ELISA Kit, SOST ELISA Kit, Sost ELISA Kit
    背景

    Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .

    Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.

    Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,

    Full Gene Name: Sclerostin

    Cellular Localisation: Secreted, extracellular space, extracellular matrix.
    UniProt
    Q9BQB4
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