anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) 抗体

The protein encoded by ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). 再加上,我们可以发ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 试剂盒 (18)ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ST8SIA4 20452 Q64692
ST8SIA4 7903 Q92187
ST8SIA4 116696  
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antibodies-online.cn销售最多的anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 抗体

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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-ST8SIA4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-St8sia4 Antibody   Titration: 1.0 ug/ml   Positive Control: Rat Testis 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 FACS, IHC (p), WB Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in HL-60 cell line lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ST8SIA4 Antibody (Center) (ABIN653728) in mouse spleen tissue lysates (35 µg/lane). ST8SIA4 (arrow) was detected using the purified polyclonal antibody. ST8SIA4 Antibody (Center) (ABIN653728) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
$385.00
详细
非结合性 IHC (p), WB   0.4 mL Log in to see 4至8个工作日
$522.50
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非结合性 FACS, IHC (p), WB Western blot analysis of ST8SIA4 Antibody in HL-60 cell line lysates (35ug/lane) Western blot analysis of ST8SIA4 Antibody in mouse spleen tissue lysates (35ug/lane) ST8SIA4 Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2至3个工作日
$515.63
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非结合性 ELISA, WB 100 μL Log in to see 2至3个工作日
$446.88
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非结合性 WB ST8SIA4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
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Yeast 非结合性 ELISA, WB Western blot analysis of PST1 in Yeast with PST1 polyclonal antibody  at 1 ug/mL. 100 μg Log in to see 11至12个工作日
$356.00
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非结合性 WB Western blot analysis of extracts of various cell lines, using ST8SIA4 Antibody. 200 μL Log in to see 12至14个工作日
$438.90
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Yeast 非结合性 ELISA, WB Western blot analysis of TM yeast Pst1 protein (50 ng) with Pst1 antibody at 1 µg/mL. 0.1 mg Log in to see 2至3个工作日
$360.00
详细

更多抗ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4的相互作用对抗体

Mouse (Murine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Mice deficient for ST8SiaIV have impaired long-term spatial memory in two tasks that critically rely on the hippocampus.

  2. Results demonstrate that the early development of calbindin-positive periglomerular interneurons depends on the presentation of polysialic acid on NCAM and requires the activity of both St8sia2 and St8sia4

  3. NCAM-140 significantly promoted cell proliferation, motility and migration, while polysialylation of NCAM-140 catalyzed by STX, but not by PST, enhanced NCAM-mediated cell migration, but not cell proliferation or motility.

  4. ST8SiaIV synthesized polySia selectively on a NRP2 glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

  5. Results indicate that the polySTs ST8SiaII and ST8SiaIV not only recognize an acidic patch in the FN1 domain of NCAM but also must contact sequences in the Ig5 domain for polysialylation of Ig5 N-glycans to occur.

  6. the negative and positive effects of ST8SiaIV overexpression observed during peripheral nerve regeneration suggest that an optimized time- and differentiation-dependent control of expression in Schwann cells may further improve nerve regeneration

  7. While both ST8SiaII and ST8SiaIV mRNA levels decrease around the time of eye opening in mouse visual cortex, only ST8SiaII mRNA level reduction is regulated by sensory experience

  8. ST8Sia4 knockout mice display a decreased motivation in social interaction. This deficit can be partly explained by olfactory deficits and was associated with a clear decrease in PSA-NCAM expression in all brain regions analyzed.

  9. This study demonistrated that mice lacking St8siaIV polysialyltransferase have an accelerated onset of remyelination after cuprizone-induced demyelination.

  10. In summary, the data suggest that the polysialic acid-neural cell adhesion molecule system is a putative target for the modulation of

  11. Focusing on the cerebral cortex, our results indicate that ST8SiaIV is solely responsible for PSA expression in mature interneurons and in most regions of cortical neuropil.

  12. the coordinated action of ST8SiaII and ST8SiaIV is crucial to fine-tune the amount and structure of polySia on NCAM

  13. The developmental changes in neural cell adhesion molecule polysialylation in wild-type, ST8SiaII-, and ST8SiaIV-deficient mice from postnatal days 1 to 21 and from adult mice, was monitored.

Human ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Different properties of polysialic acids synthesized by the polysialyltransferases ST8SIA2 and ST8SIA4 have been described.

  2. our results demonstrate that miR-146a and miR-146b promote proliferation, migration and invasion of FTC via inhibition of ST8SIA4.

  3. Data show that miR-181c was inversely correlated with the levels of ST8SIA4 expression in chronic myelocytic leukemia (CML) cell lines and samples.

  4. This is the first report to demonstrate a role for a glycosyltransferase in human pluripotent stem cell lineage specification.

  5. changes in the glycosylation patterns and sialylation levels may be useful markers of the progression of breast cancer, as well as miR-26a/26b may be widely involved in the regulation of sialylation machinery by targeting ST8SIA4.

  6. The polybasic region of the polysialyltransferase ST8Sia-IV binds directly to NCAM.

  7. Sequence Requirements for Neuropilin-2 Recognition by ST8SiaIV and Polysialylation of Its O-Glycans.

  8. ST8SIA4 gene is involved in the development of multidrug resistance via PI3K/Akt pathway in chronic myeloid leukemia.

  9. this study indicated that sialylation involved in the development of MDR of AML cells probably through ST3GAL5 or ST8SIA4 regulating the activity of PI3K/Akt signaling and the expression of P-gp and MRP1.

  10. ST8SiaIV synthesized polySia selectively on a NRP2 glycoform that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

  11. The ST8SiaIV/PST polybasic region plays a critical role in substrate recognition.

  12. polysialylated NCAM persistence, up-regulated polysialyltransferase-1 mRNA and previously uncovered defective myelin-associated glycoprotein may be early pathogenetic events in adult-onset autosomal-dominant leukodystrophy

  13. SIAT8D has a role in neural development and sialic acid synthesis on NCAM

  14. Pancreatitis risk was highest in individuals with abnormalities in pancreatic duct(CFTR) and acini (PST1) indicating that PST1 is a modifier gene for CFTR-related idiopathic chronic pancreatitis.

  15. The upregulation of ST8SIA4 and the donwregulation of ST8SIA2 by valproic acid in HUVEC and tumor cell lines are reported.

  16. polysialyltransferase ST8Sia IV/PST recognizes specific amino acids in the first fibronectin type III repeat of the neural cell adhesion molecule

  17. PSA-NCAM and ST8Sia-II/IV Expression Is Increased in Pancreatic Carcinomas

  18. Amino acid substitutions in conserved sequences are critical for the protein-specific polysialylation of NCAM.

Pig (Porcine) ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) interaction partners

  1. Pig cDNA provides a basis for uncovering the roles of ST8Sia IV during piglet development and maturation.

ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) 抗原简介

蛋白简介

The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ST8SIA4

  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (St8sia4) 抗体
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (ST8SIA4) 抗体
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 (st8sia4) 抗体
  • pst 抗体
  • PST-1 抗体
  • PST1 抗体
  • SIAT8-D 抗体
  • SIAT8D 抗体
  • siat 8D 抗体
  • ST8Sia-IV 抗体
  • ST8SiaIV 抗体

Protein level used designations for ST8SIA4

CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase , alpha-2,8-sialyltransferase 8D , polysialyltransferase-1 , sialyltransferase 8 (alpha-2, 8-sialyltransferase) D , sialyltransferase 8D , sialyltransferase St8Sia IV , sialytransferase St8Sia IV , CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase , SIAT8-D , ST8SiaIV , sialyltransferase 8 (alpha-2, 8-polysialytransferase) D , ST8Sia IV , polysialyltransferase , sialyltransferase 8 (alpha-2 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2 8-polysialytransferase) D , sialyltransferase 8 (alpha-2, 8-polysialyltransferase) D , sialyltransferase 8 (alpha-2, 8-sialytransferase) D , sialyltransferase 8D (alpha-2, 8-polysialyltransferase) , alpha-2,8-polysialyltransferase IV , polysialyltransferase 1 , N-glycan alpha 2,8-sialyltransferase , alpha-2,8-sialyltransferase ST8Sia IV , CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase-like protein

GENE ID SPECIES
20452 Mus musculus
7903 Homo sapiens
407768 Bos taurus
116696 Rattus norvegicus
374155 Gallus gallus
488886 Canis lupus familiaris
641356 Sus scrofa
461971 Pan troglodytes
101112314 Ovis aries
100716689 Cavia porcellus
553211 Danio rerio
100064780 Equus caballus
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