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ST8SIA4 抗体 (N-Term)

ST8SIA4 适用: Saccharomyces cerevisiae WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990643
发货至: 中国
  • 抗原 See all ST8SIA4 抗体
    ST8SIA4 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4))
    抗原表位
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 80-130, N-Term
    适用
    • 37
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    • 4
    • 4
    • 4
    • 4
    • 4
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    • 2
    • 2
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    • 1
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    • 1
    Saccharomyces cerevisiae
    宿主
    • 35
    • 2
    克隆类型
    • 35
    • 2
    多克隆
    标记
    • 16
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ST8SIA4 antibody is un-conjugated
    应用范围
    • 23
    • 21
    • 14
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    Pst1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Pst1 antibody was raised against a synthetic peptide from the amino terminus of yeast Pst1. The immunogen is located within amino acids 80 - 130 of Pst1.
    亚型
    IgG
    Top Product
    Discover our top product ST8SIA4 Primary Antibody
  • 应用备注
    Pst1 antibody can be used for detection of Pst1 by Western blot and ELISA at 1 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Pst1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Pst1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ST8SIA4 (ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4))
    别名
    Pst1 (ST8SIA4 产品)
    别名
    PST antibody, PST-1 antibody, SIAT8-D antibody, ST8SiaIV antibody, Siat8d antibody, PST1 antibody, SIAT8D antibody, ST8SIA-IV antibody, ST8Sia-IV antibody, pst antibody, siat 8D antibody, ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 antibody, St8sia4 antibody, ST8SIA4 antibody, st8sia4 antibody
    背景
    Pst1 Antibody: Protoplast secreted protein 1 (Pst1) is an anchored plasma membrane protein. Pst1 was previously identified as a protein secreted by yeast regenerating protoplasts, which suggests a role in cell wall construction. Pst1 is a protein with 444 amino acids and is attached to yeast cell wall via a glycosylphosphatidylinisotol (GPI) anchor. Pst1 contains 15 potential N-linked glycosylation sites and is heavily glycosylated. It migrates at approximately 200 kDa on SDS-PAGE when produced in wild type S. cerevisiae. Our Pst1 protein (Catalog No. 95-151) was expressed in a genetically manipulated triple-mutant (TM) S. cerevisiae stain (Δ,och1 Δ,mnn1 Δ,mnn4), which results in the production of sole Man8GlcNAc2 carbohydrate structures and Pst1 migration at approximately 100 kDa. When produced in the TM yeast, Pst1 can be recognized by several glycan-specific HIV-1 broadly neutralizing antibodies, including 2G12 and recently identified PGT antibodies. Among several heavily N-glycosylated TM yeast glycoproteins, Pst1 shows higher affinity for 2G12 and efficiently inhibits gp120 interactions with 2G12 and DC-SIGN, and it also blocks 2G12-mediated neutralization of HIV-1 pseudoviruses.
    分子量
    49 kDa
    基因ID
    851625
    UniProt
    Q12355
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