蛋白简介

mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

Gene names and symbols associated with anti-SARS-CoV-2 Spike 抗体

• Surface Glycoprotein (S) 抗体

• E2 抗体

Protein level used designations for anti-SARS-CoV-2 Spike 抗体

Peplomer protein , S Protein , S glycoprotein , S-Protein , Spike , Spike Protein , Spike glycoprotein