anti-Runt-Related Transcription Factor 3 (RUNX3) 抗体

RUNX3 encodes a member of the runt domain-containing family of transcription factors. 再加上,我们可以发RUNX3 蛋白 (11)RUNX3 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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antibodies-online.cn销售最多的anti-RUNX3 抗体

Showing 10 out of 231 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 EMSA AML-2/Runx3 antibody tested by supershift. Detection of AML-2/Runx3 by EMSA analysis. AML-2/Runx3 antibody was used in a supershift assay (EMSA) with Raji nuclear extract (lane 4). 100 μL Log in to see 1至2个工作日
$495.83
详细
小鼠 非结合性 ICS, IHC (p), WB   0.1 mg Log in to see 15至18个工作日
$238.84
详细
Cow 非结合性 WB WB Suggested Anti-RUNX3 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:12500  Positive Control:  NIH/3T3 cell lysate 100 μL Log in to see 2至3个工作日
$229.00
详细
小鸡 非结合性 WB Western blot analysis of RUNX3 expression in Jurkat (A), Raji (B), SW480 (C) whole cell lysates. 200 μL Log in to see 13至14个工作日
$487.50
详细
非结合性 IHC (p), WB Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Rat Spleen Tissue Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4至6个工作日
$280.00
详细
小鼠 APC FACS Detection of RUNX3/CBFA3 in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cells (PBMC) lymphocytes either (A) untreated or (B) treated with PMA were stained with Mouse Anti-Human RUNX3/CBFA3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8至9个工作日
$393.30
详细
小鼠 非结合性 CyTOF, FACS, ICC, SimWes, WB Detection of Human RUNX3/CBFA3 by Simple WesternTM. Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line, loaded at 0.5 mg/mL. A specific band was detected for RUNX3/CBFA3 at approximately 54 kDa (as indicated) using 10 ug/mL of Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Detection of RUNX3/CBFA3 in Human PBMC by Flow Cytometry. Human PBMC unstimulated (light orange filled histogram) or treated with 50ng/mL PMA (dark orange filled histogram) were stained with Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8至9个工作日
$297.85
详细
小鼠 非结合性 ICC, FACS, IHC, ELISA, WB 100 μg Log in to see 2至3个工作日
$430.10
详细
小鼠 非结合性 ELISA, FACS, IF/ICC, IHC, WB 100 μg Log in to see 11至16个工作日
$426.40
详细
Cow 非结合性 WB 100 μg Log in to see 7至9个工作日
$493.17
详细

通过反应活性、应用领域、克隆类型和共轭标记 RUNX3 抗体

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引用最多的anti-RUNX3 抗体

  1. Human Polyclonal RUNX3 Primary Antibody for EMSA - ABIN3434042 : Peng, Wei, Wang, Tang, Zhang, Le, Jia, Li, Xie: RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)
    Show all 6 Pubmed References

  2. Human Monoclonal RUNX3 Primary Antibody for ICS, IHC (p) - ABIN2689899 : Chuang, Ito, Ito: RUNX family: Regulation and diversification of roles through interacting proteins. in International journal of cancer. Journal international du cancer 2013 (PubMed)
    Show all 6 Pubmed References

  3. Human Polyclonal RUNX3 Primary Antibody for ELISA, WB - ABIN560191 : Nakamura, Senzaki, Yoshikawa, Nishimura, Inoue, Ito, Ozaki, Shiga: Dynamic regulation of the expression of neurotrophin receptors by Runx3. in Development (Cambridge, England) 2008 (PubMed)
    Show all 5 Pubmed References

  4. Human Monoclonal RUNX3 Primary Antibody for CyTOF, FACS - ABIN4899364 : Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. in The Journal of experimental medicine 2013 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal RUNX3 Primary Antibody for IF, IHC (p) - ABIN514065 : Shi, Wang, Liu, Chen: Inactivation of RUNX3 predicts poor prognosis in esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy. in Medical oncology (Northwood, London, England) 2014 (PubMed)

  6. Human Polyclonal RUNX3 Primary Antibody for IF, IHC (p) - ABIN658684 : Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma. in Journal of experimental & clinical cancer research : CR 2015 (PubMed)

  7. Human Monoclonal RUNX3 Primary Antibody for ICC, FACS - ABIN1724742 : Mei, Bai, Liu, Li, Wu, Yu, Zheng: RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. in Journal of cancer research and clinical oncology 2011 (PubMed)

更多抗RUNX3的相互作用对抗体

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. In neuronal fate determination, Runx co-factor Cbfbeta (显示 CBFB 抗体) is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta (显示 CBFB 抗体), demonstrating that Cbfbeta (显示 CBFB 抗体) in this context serves solely as a signal amplifier of Runx3 activity.

  2. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  3. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (显示 RUNX1 抗体)-expressing cells in the ventral wall of the dorsal aorta.

  4. Zebrafish embryos lacking Rad21 (显示 RAD21 抗体), or cohesin subunit Smc3 (显示 SMC3 抗体), fail to express runx3 and lose hematopoietic runx1 (显示 RUNX1 抗体) expression in early embryonic development.

Pig (Porcine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. The promoter regions of Runx3 is targets of STAT4 (显示 STAT4 抗体) and that STAT4 (显示 STAT4 抗体) binding during NK cell activation induces epigenetic modifications of Runx3 gene loci resulting in increased expression.

  2. Runx3 programs CD8 (显示 CD8A 抗体)(+) T cell residency in non-lymphoid tissues and tumours; results provide insight into the signals that promote T cell residency in non-lymphoid sites, which could be used to enhance vaccine efficacy or adoptive cell therapy treatments that target cancer

  3. Findings suggest that Runx3 may regulate cell shape to inhibit melanoma cell migration partly through enhancing stress fiber formation and ECM (显示 MMRN1 抗体) protein production.

  4. The findings suggest that the absence of uPA (显示 PLAU 抗体) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.

  5. Runx3-deficient CD8 (显示 CD8A 抗体)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (显示 BCL6 抗体), Tcf7 (显示 TCF7 抗体) and Cxcr5 (显示 CXCR5 抗体). Mechanistically, the Runx3-CBFbeta (显示 CBFB 抗体) transcription factor complex deployed H3K27me3 to Bcl6 (显示 BCL6 抗体) and Tcf7 (显示 TCF7 抗体) genes to suppress the TFH program.

  6. Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.

  7. We found that Runx3 exerted a positive effect on early myeloid development

  8. Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis

  9. intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (显示 NTRK3 抗体) neurons while concomitantly extinguishing its expression in non-TrkC (显示 NTRK3 抗体) neurons

  10. this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection

Human Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. MiR (显示 MLXIP 抗体)-182/HOXA9 (显示 HOXA9 抗体) was involved in the process of RUNX3-mediated GC tumor growth.

  2. The BMP9 (显示 GDF2 抗体)-induced phosphorylation of Smad1 (显示 GARS 抗体)/5/8 was increased with the overexpression of RUNX3, and yet was decreased with the knockdown of RUNX3. Collectively, our findings suggest that RUNX3 is an essential modulator of the BMP9 (显示 GDF2 抗体)-induced osteoblast lineage differentiation of mesenchymal stem cells (MSCs).

  3. results suggest that EZH2 (显示 EZH2 抗体) regulates cell proliferation potentially by targeting RUNX3 through the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway in laryngeal carcinoma.

  4. These findings suggested that RUNX3 played a tumor suppressor role in oral squamous cell carcinoma (OSCC) by inhibiting cell migration, invasion and angiogenesis, supporting that it could be a potential therapeutic target for OSCC

  5. Study showed that Runx3 was found a target of miR (显示 MLXIP 抗体)-106b, and the inhibition of miR (显示 MLXIP 抗体)-106b upregulated Runx3. These results provide evidence that Runx3 is a tumor-suppressor in retinoblastoma and is a target of miR (显示 MLXIP 抗体)-106b.

  6. Our results support the ability of Runx3 to contribute to the dissemination of human PDAC thus confirming the observations from murine models.

  7. High expression of RUNX3 is correlated with gastric cancer.

  8. RUNX3 is a common downstream target of TGF-beta (显示 TGFB1 抗体) and Notch (显示 NOTCH1 抗体) signaling, and may be a novel therapeutic target for treating CVD mediated by EndMT.

  9. CNRIP1 (显示 Cnrip1 抗体) and RUNX3 as potential DNA methylation (显示 HELLS 抗体) biomarkers for CRC (显示 CALR 抗体) diagnosis and treatment

  10. RUNX3 expression in oral squamous carcinoma cells contributes to their bone invasion and the resulting osteolysis by inducing their malignant behaviors and production of osteolytic factors.

RUNX3 抗原简介

蛋白简介

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX3

  • runt-related transcription factor 3 (runx3) 抗体
  • runt-related transcription factor 3 (RUNX3) 抗体
  • runt related transcription factor 3 (RUNX3) 抗体
  • runt related transcription factor 3 (runx3) 抗体
  • runt related transcription factor 3 L homeolog (runx3.L) 抗体
  • runt related transcription factor 3 (Runx3) 抗体
  • runt-related transcription factor 3 (Runx3) 抗体
  • AML2 抗体
  • Cbfa3 抗体
  • frrunx3 抗体
  • Pebp2a3 抗体
  • PEBP2aC 抗体
  • runx3 抗体
  • runxb 抗体

Protein level used designations for RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

GENE ID SPECIES
58127 Danio rerio
403159 Sus scrofa
456633 Pan troglodytes
100049632 Takifugu rubripes
100474431 Ailuropoda melanoleuca
100500732 Xenopus laevis
12399 Mus musculus
864 Homo sapiens
617389 Bos taurus
156726 Rattus norvegicus
769687 Gallus gallus
487366 Canis lupus familiaris
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