Use your antibodies-online credentials, if available.
RUNX3 encodes a member of the runt domain-containing family of transcription factors. 再加上，我们可以发RUNX3 蛋白 (11) 和 RUNX3 试剂盒 (5)和数多这个蛋白质的别的产品。
Showing 10 out of 231 products:
Human Polyclonal RUNX3 Primary Antibody for EMSA - ABIN3434042
Peng, Wei, Wang, Tang, Zhang, Le, Jia, Li, Xie: RUNX3 inhibits the expression of vascular endothelial growth factor and reduces the angiogenesis, growth, and metastasis of human gastric cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Show all 6 Pubmed References
Human Monoclonal RUNX3 Primary Antibody for ICS, IHC (p) - ABIN2689899
Chuang, Ito, Ito: RUNX family: Regulation and diversification of roles through interacting proteins. in International journal of cancer. Journal international du cancer 2013
Show all 6 Pubmed References
Human Polyclonal RUNX3 Primary Antibody for ELISA, WB - ABIN560191
Nakamura, Senzaki, Yoshikawa, Nishimura, Inoue, Ito, Ozaki, Shiga: Dynamic regulation of the expression of neurotrophin receptors by Runx3. in Development (Cambridge, England) 2008
Show all 5 Pubmed References
Human Monoclonal RUNX3 Primary Antibody for CyTOF, FACS - ABIN4899364
Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. in The Journal of experimental medicine 2013
Show all 2 Pubmed References
Human Polyclonal RUNX3 Primary Antibody for IF, IHC (p) - ABIN514065
Shi, Wang, Liu, Chen: Inactivation of RUNX3 predicts poor prognosis in esophageal squamous cell carcinoma after Ivor-Lewis esophagectomy. in Medical oncology (Northwood, London, England) 2014
Human Polyclonal RUNX3 Primary Antibody for IF, IHC (p) - ABIN658684
Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma. in Journal of experimental & clinical cancer research : CR 2015
Human Monoclonal RUNX3 Primary Antibody for ICC, FACS - ABIN1724742
Mei, Bai, Liu, Li, Wu, Yu, Zheng: RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. in Journal of cancer research and clinical oncology 2011
In neuronal fate determination, Runx co-factor Cbfbeta (显示 CBFB 抗体) is essential for its function, but the high level of Runx3 expression can overcome the loss of Cbfbeta (显示 CBFB 抗体), demonstrating that Cbfbeta (显示 CBFB 抗体) in this context serves solely as a signal amplifier of Runx3 activity.
successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish
Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (显示 RUNX1 抗体)-expressing cells in the ventral wall of the dorsal aorta.
Zebrafish embryos lacking Rad21 (显示 RAD21 抗体), or cohesin subunit Smc3 (显示 SMC3 抗体), fail to express runx3 and lose hematopoietic runx1 (显示 RUNX1 抗体) expression in early embryonic development.
These results demonstrate that the CRISPR/Cas9 system is effective in inducing mutations on a specific locus of genome and the RUNX3 knockout pigs can be useful resources for human cancer research and to develop novel cancer therapies.
The promoter regions of Runx3 is targets of STAT4 (显示 STAT4 抗体) and that STAT4 (显示 STAT4 抗体) binding during NK cell activation induces epigenetic modifications of Runx3 gene loci resulting in increased expression.
Runx3 programs CD8 (显示 CD8A 抗体)(+) T cell residency in non-lymphoid tissues and tumours; results provide insight into the signals that promote T cell residency in non-lymphoid sites, which could be used to enhance vaccine efficacy or adoptive cell therapy treatments that target cancer
Findings suggest that Runx3 may regulate cell shape to inhibit melanoma cell migration partly through enhancing stress fiber formation and ECM (显示 MMRN1 抗体) protein production.
The findings suggest that the absence of uPA (显示 PLAU 抗体) correlates with increased levels of Runx transcriptional regulators in a way that promotes inflammation-associated carcinogenesis.
Runx3-deficient CD8 (显示 CD8A 抗体)(+) cytotoxic effector T cells aberrantly upregulated genes characteristic of follicular helper T (TFH) cell lineage, including Bcl6 (显示 BCL6 抗体), Tcf7 (显示 TCF7 抗体) and Cxcr5 (显示 CXCR5 抗体). Mechanistically, the Runx3-CBFbeta (显示 CBFB 抗体) transcription factor complex deployed H3K27me3 to Bcl6 (显示 BCL6 抗体) and Tcf7 (显示 TCF7 抗体) genes to suppress the TFH program.
Deletion of Runx3 in the peripheral nervous system or specifically in peripheral sensory neurons, or of enhancer elements driving Runx3 expression in proprioceptive neurons, induced prepubertal scoliosis.
We found that Runx3 exerted a positive effect on early myeloid development
Runx3 plays a crucial role in the hypothalamo-pituitary-gonadal axis
intricate combinatorial interplay among the three regulatory elements governs Runx3 expression in distinct subtypes of TrkC (显示 NTRK3 抗体) neurons while concomitantly extinguishing its expression in non-TrkC (显示 NTRK3 抗体) neurons
this study identifies a compensatory signaling mechanism that prevents lineage-fate errors by dynamically modulating Runx3d induction rates during MHC I positive selection
MiR (显示 MLXIP 抗体)-182/HOXA9 (显示 HOXA9 抗体) was involved in the process of RUNX3-mediated GC tumor growth.
The BMP9 (显示 GDF2 抗体)-induced phosphorylation of Smad1 (显示 GARS 抗体)/5/8 was increased with the overexpression of RUNX3, and yet was decreased with the knockdown of RUNX3. Collectively, our findings suggest that RUNX3 is an essential modulator of the BMP9 (显示 GDF2 抗体)-induced osteoblast lineage differentiation of mesenchymal stem cells (MSCs).
results suggest that EZH2 (显示 EZH2 抗体) regulates cell proliferation potentially by targeting RUNX3 through the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway in laryngeal carcinoma.
These findings suggested that RUNX3 played a tumor suppressor role in oral squamous cell carcinoma (OSCC) by inhibiting cell migration, invasion and angiogenesis, supporting that it could be a potential therapeutic target for OSCC
Study showed that Runx3 was found a target of miR (显示 MLXIP 抗体)-106b, and the inhibition of miR (显示 MLXIP 抗体)-106b upregulated Runx3. These results provide evidence that Runx3 is a tumor-suppressor in retinoblastoma and is a target of miR (显示 MLXIP 抗体)-106b.
Our results support the ability of Runx3 to contribute to the dissemination of human PDAC thus confirming the observations from murine models.
High expression of RUNX3 is correlated with gastric cancer.
RUNX3 is a common downstream target of TGF-beta (显示 TGFB1 抗体) and Notch (显示 NOTCH1 抗体) signaling, and may be a novel therapeutic target for treating CVD mediated by EndMT.
CNRIP1 (显示 Cnrip1 抗体) and RUNX3 as potential DNA methylation (显示 HELLS 抗体) biomarkers for CRC (显示 CALR 抗体) diagnosis and treatment
RUNX3 expression in oral squamous carcinoma cells contributes to their bone invasion and the resulting osteolysis by inducing their malignant behaviors and production of osteolytic factors.
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
runt-related transcription factor b
, runt-related transcription factor 3
, core-binding factor 3
, PEA2-alpha C
, PEBP2-alpha C
, SL3-3 enhancer factor 1 alpha C subunit
, SL3/AKV core-binding factor alpha C subunit
, acute myeloid leukemia 2 protein
, core binding factor alpha 3
, core-binding factor subunit alpha-3
, oncogene AML-2
, polyomavirus enhancer-binding protein 2 alpha C subunit
, runt domain, alpha subunit 3
, transcription factor AML2/CBFA3
, PEA2 alpha C
, PEBP2 alpha C
, acute myeloid leukemia gene 2
, core-binding factor, runt domain, alpha subunit 3
, transcription factor AML2
, Runt related transcription factor 3
, Runx3 MASN-variant