anti-Ring Finger Protein 139 (RNF139) 抗体

The protein encoded by RNF139 is a multi-membrane spanning protein containing a RING-H2 finger. 再加上,我们可以发Ring Finger Protein 139 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
RNF139 11236 Q8WU17
RNF139 75841 Q7TMV1
RNF139 315000  
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antibodies-online.cn销售最多的anti-Ring Finger Protein 139 抗体

Showing 10 out of 58 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-RNF139 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  MCF7 cell lysate RNF139 is supported by BioGPS gene expression data to be expressed in MCF7 100 μL 2至3个工作日
山羊 非结合性 IHC, ELISA, WB (1µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg 6至7个工作日
山羊 非结合性 ELISA, IHC, IHC (p), WB 50 μg 11至14个工作日
Bat 非结合性 IHC, IHC (p), WB 100 μL 11至14个工作日
小鼠 非结合性 IHC (p), ELISA, WB RNF139 monoclonal antibody (M01), clone 3D10 Western Blot analysis of RNF139 expression in HepG2 . Detection limit for recombinant GST tagged RNF139 is approximately 0.03ng/ml as a capture antibody. 100 μg 11至12个工作日
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL 11至12个工作日
山羊 非结合性 EIA, IHC (p), WB   0.1 mg 4至8个工作日
小鼠 非结合性 ELISA, WB 100 μg 11至14个工作日
非结合性 ELISA, WB 100 μL 2至3个工作日
非结合性 WB RNF139 antibody used at 1 ug/ml to detect target protein. 50 μg 9至11个工作日

引用最多的anti-Ring Finger Protein 139 抗体

  1. Human Polyclonal RNF139 Primary Antibody for ELISA, WB - ABIN564886 : Brauweiler, Lorick, Lee, Tsai, Chan, Weissman, Drabkin, Gemmill: RING-dependent tumor suppression and G2/M arrest induced by the TRC8 hereditary kidney cancer gene. in Oncogene 2007 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal RNF139 Primary Antibody for IHC (p), ELISA - ABIN564887 : Adams, Simms, Abdelhamed, Dawe, Szymanska, Logan, Wheway, Pitt, Gull, Knowles, Blair, Cross, Sayer, Johnson: A meckelin-filamin A interaction mediates ciliogenesis. in Human molecular genetics 2012 (PubMed)

更多抗Ring Finger Protein 139的相互作用对抗体

Human Ring Finger Protein 139 (RNF139) interaction partners

  1. INSIG1 coordinated with another ligase, translocation in renal carcinoma chromosome 8 (TRC8), and promoted Gag degradation through the lysosome pathway.

  2. TRC8 and MARCH6 depletion altered the turnover of the tail-anchored protein heme oxygenase-1.

  3. Low RNF139 expression is associated with progression of tongue cancer.

  4. interaction with Bag1 then shifts hERG degradation to the membrane-anchored E3 ligase TRC8 and its E2-conjugating enzyme Ube2g2, as determined by siRNA screening

  5. TRC8 and TMEM129 are endoplasmic reticulum-associated degradation ubiquitin E3 ligases for viral and cellular targeting of MHC class I. (Review)

  6. TRC8 suppresses tumorigenesis through targeting heme oxygenase-1 for ubiquitination and degradation.

  7. TRC8 function may provide a regulatory link between the lipid and protein biosynthetic pathways.

  8. TRC8 modulation of sterol response element binding protein activity comprises a novel regulatory link between growth control and the cholesterol/lipid homeostasis pathway.

  9. The presence of diploid and tetraploid tumor cells with and without TRC8 deletions on the nontranslocated chromosome suggest that loss of the remaining normal allele of TRC8 may contribute to tumor development at later stages.

  10. TRC8 is a novel sterol-sensing endoplasmic reticulum membrane protein that hinders SREBP-2 processing through interaction with SREBP-2 and SCAP, regulating its own turnover rate by means of its E3 ubiquitin ligase activity

  11. Data show that the TRC8 E3 ligase is required for MHC I dislocation from the ER and identify a new complex associated with mammalian ERAD.

Ring Finger Protein 139 (RNF139) 抗原简介


The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.

Gene names and symbols associated with RNF139

  • ring finger protein 139 (RNF139) 抗体
  • ring finger protein 139 (Rnf139) 抗体
  • ring finger protein 139 (rnf139) 抗体
  • ring finger protein 139 S homeolog (rnf139.S) 抗体
  • 4930555P18Rik 抗体
  • HRCA1 抗体
  • RCA1 抗体
  • rnf139 抗体
  • TRC8 抗体
  • zgc:175173 抗体

Protein level used designations for RNF139

E3 ubiquitin-protein ligase RNF139 , multiple membrane spanning receptor TRC8 , patched related protein translocated in renal cancer , translocation in renal carcinoma on chromosome 8 protein , RING finger protein 139 , ring finger protein 139 S homeolog

11236 Homo sapiens
75841 Mus musculus
315000 Rattus norvegicus
420338 Gallus gallus
609422 Canis lupus familiaris
100067392 Equus caballus
100156613 Sus scrofa
788471 Bos taurus
100447707 Pongo abelii
100734055 Cavia porcellus
100357210 Oryctolagus cuniculus
100144552 Danio rerio
444792 Xenopus laevis
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