Regenerating Islet-Derived 3 alpha 蛋白 (REG3A)

REG3A encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. 再加上，我们可以发REG3A 抗体 (121) 和 REG3A 试剂盒 (54)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
REG3A 5068 Q06141
REG3A 19694 O09037
REG3A 171162 P35231
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells 人 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$6,869.04
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人细胞 小鼠 His tag 100 μg Log in to see 20至21个工作日
$382.80
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人细胞 人 His tag 100 μg Log in to see 14至16个工作日
$492.80
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人细胞 大鼠 His tag 100 μg Log in to see 20至21个工作日
$382.80
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HEK-293 Cells 人 Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see Available
$814.00
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大肠杆菌（E. Coli） 人 GST tag 100 μg Log in to see 11 Days
$411.40
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大肠杆菌（E. Coli） 大鼠 His tag 100 μg Log in to see 11 Days
$581.90
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小麦胚 人 GST tag 10 μg Log in to see 11至12个工作日
$414.29
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大肠杆菌（E. Coli） 人 非结合性 SDS-PAGE analysis of Human REG3a Protein. 100 μg Log in to see 11至18个工作日
$625.39
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REG3A 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
, ,
Mouse (Murine) , ,

Rat (Rattus) , ,
, ,

引用最多的REG3A 蛋白

  1. Human REG3A Protein expressed in Human Cells - ABIN3216396 : Orelle, Keim, Masciotra, Dagorn, Iovanna: Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases. in The Journal of clinical investigation 1993 (PubMed)
    Show all 3 Pubmed References

更多Regenerating Islet-Derived 3 alpha (REG3A)互动伙伴

Human Regenerating Islet-Derived 3 alpha (REG3A) interaction partners

  1. Data show that regenerating family member 3 alpha protein (REG3A) can modulate specific cutaneous inflammatory responses and that the decrease in cutaneous REG3A exacerbates toll-like receptor 3 (TLR3 (显示 TLR3 蛋白))-mediated inflammation in diabetic skin wounds.

  2. Data found that REG3A was significantly downregulated in Gastric cancer and closely related with patient prognoses. REG3A overexpression suppressed the invasion and proliferation promoting apoptosis of GC cells. While REG3A knockdown promoted the invasion, and proliferation suppressing

  3. Mice with hepatocytes that express hREG3A, which travels to the intestinal lumen, are less sensitive to colitis than control mice. Suggest reduced oxidative stress preserves the gut (显示 GUSB 蛋白) microbiota and its ability to prevent inflammation.

  4. The pancreas reacts to remote lesions and septic insults in mice and rats with increased PSP (显示 MSMB 蛋白) synthesis, while PAP is selectively responsive to septic events. Furthermore, our results suggest that serum PSP (显示 MSMB 蛋白) in septic patients is predominantly derived through an acute phase response of the pancreas.

  5. Data show that interleukin-2 receptor alpha (显示 IL2RA 蛋白), tumor necrosis factor receptor 1 (显示 TNFRSF1A 蛋白), serum STimulation-2 (IL1RL1 (显示 IL1RL1 蛋白) gene product), and regenerating islet-derived 3-alpha were significantly associated with non-relapse mortality.

  6. skin injury increases IL-36gamma via the activation of TLR3 (显示 TLR3 蛋白)-SLUG-VDR (显示 CYP27B1 蛋白) axis and IL-36gamma induces REG3A to promote wound healing

  7. Association between a SNP in the REG3A gene, rs7588571, located upstream of the REG3A gene, and bone marrow transplant outcomes including the incidence of chronic GVHD. Since REG (显示 EXTL3 蛋白) proteins control intestinal microbiota, and since intestinal dysbiosis is in part responsible for the development of GVHD, findings lead to the concept that REG3A could have some protective effect through the regulation of gut (显示 GUSB 蛋白) microbiota.

  8. Patients with high levels of PAP/REG3A had overall shorter survival as well as poor surgical outcomes with reduced disease-free survival.

  9. Up-regulation of REG3A correlates with colorectal cancer risk.

  10. Regulation network analysis confirmed the cell growth related differentially expressed genes, and further uncovered three transcription factor families with immune functions regulated by REG3A

Mouse (Murine) Regenerating Islet-Derived 3 alpha (REG3A) interaction partners

  1. skin injury increases IL-36gamma via the activation of TLR3 (显示 TLR3 蛋白)-SLUG-VDR (显示 CYP27B1 蛋白) axis and IL-36gamma induces REG3A to promote wound healing

  2. Data show that regenerating islet-derived 3-alpha (REG3alpha) is a plasma biomarker of gastrointestinal tract graft-versus-host disease that can be combined with clinical stage and histologic grade to improve risk stratification of patients.

  3. Reg2 (显示 FLOT1 蛋白), Reg3alpha, and Reg3beta were abundantly expressed in most acinar cells of the pancreas with clear age-dependent and isoform-specific patterns.

  4. Reg3alpha stimulates beta-cell replication, by activating Akt (显示 AKT1 蛋白) kinase and increasing the levels of cyclin D1 (显示 CCND1 蛋白)/CDK4 (显示 CDK4 蛋白).

蛋白简介REG3A

蛋白简介

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with REG3A

  • regenerating family member 3 alpha (REG3A)
  • regenerating islet-derived 3 alpha (Reg3a)
  • regenerating islet-derived 3 alpha (REG3A)
  • AV063448 蛋白
  • HIP 蛋白
  • HIP/PAP 蛋白
  • INGAP 蛋白
  • PAP 蛋白
  • PAP-H 蛋白
  • PAP1 蛋白
  • Pap2 蛋白
  • PapII 蛋白
  • PBCGF 蛋白
  • PTP 蛋白
  • REG-III 蛋白
  • REG3 蛋白
  • REG3G 蛋白

Protein level used designations for REG3A

PAP homologous protein , REG-3-alpha , hepatocarcinoma-intestine-pancreas , hepatointestinal pancreatic protein , human proislet peptide , pancreatic beta cell growth factor , pancreatitis-associated protein 1 , proliferation-inducing protein 34 , proliferation-inducing protein 42 , reg III-alpha , regenerating islet-derived protein 3-alpha , regenerating islet-derived protein III-alpha , RegIII (alpha) , generating islet-derived, mouse homolog 3 alpha , islet of Langerhans regenerating protein 3 , lithostathine 3 , pancreatitis-associated protein 2 , REG 3 , regIII , regenerating islet-derived protein 3 alpha , ICRF , PSP , REG , islet cells regeneration factor , islet of Langerhans regenerating protein , lithostathine , pancreatic stone protein , pancreatic thread protein , pancreatitis-associated protein , regenerating islet-derived 3 gamma , regenerating islet-derived 3 alpha

GENE ID SPECIES
5068 Homo sapiens
19694 Mus musculus
171162 Rattus norvegicus
404114 Bos taurus
403411 Canis lupus familiaris
459349 Pan troglodytes
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