蛋白简介

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of this PTP suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Gene names and symbols associated with PTPRT

• protein tyrosine phosphatase, receptor type T (PTPRT) 抗体
• protein tyrosine phosphatase, receptor type, T (Ptprt) 抗体

• mKIAA0283 抗体
• RPTP-rfo 抗体
• RPTPrho 抗体

Protein level used designations for PTPRT

R-PTP-T , RPTP-rho , receptor protein tyrosine phosphatase , receptor-type tyrosine-protein phosphatase T , receptor-type tyrosine-protein phosphatase rho , RPTPmam4 , mRPTPrho , receptor protein tyrosine phosphatase-rho