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expressed in GH3 pituitary cells. 再加上，我们可以发RWD Domain Containing 3 蛋白 (8) 和 和数多这个蛋白质的别的产品。
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miR-375 was downregulated in human gliomas and overexpression of miR-375 caused downregulation of RWDD3 in glioma cells as well as inhibited their motility. Thus, these findings suggest that RWDD3 and miR-375 may function as therapeutic biomarkers for glioma patients
RSUME has a role in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
RSUME affects post-transcriptional expression of HIF-1a by regulating VEGF-A secretion and pituitary adenoma cells invasiveness.
the present report suggest that the association of RWDD3 and TECTA with paclitaxel-induced peripheral neuropathy may have been a false positive signal
an important role of RSUME in cancer and inflammation
RSUME is expressed in VHL tumors and inhibits VHL and regulates its tumor suppressor function.
this study failed to replicate a GWAS reporting an association between the 2 SNPs rs2296308 in RWDD3 and rs1829 in the intron of TECTA and time to neuropathy in ovarian cancer patients treated with paclitaxel
a degree of redundancy of the RSUME variants on the SUMO pathway
RSUME interacts with glucocorticoid receptor and increases its SUMOylation and transcriptional activity, pointing to SUMO conjugation as the cause for transcriptional stimulation.
RSUME critically regulates HIF-1a and VEGF-A production and thus might play an important role in pituitary tumour neovascularisation
RSUME plays a central role in the regulation of sumoylation and, hence, several critical regulatory pathways in mammalian cells [RSUME].
BMP-4 and RSUME may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.
expressed in GH3 pituitary cells
RWD domain containing 3
, RWD domain-containing protein 3
, RWD-containing sumoylation enhancer
, RWD domain-containing sumoylation enhancer
, pituitary tumor X2CR1 protein