anti-RAS, Dexamethasone-Induced 1 (RASD1) 抗体

RASD1 encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone.

列出全部抗体 基因 基因ID UniProt
 RASD1 RASD1 51655 Q9Y272
小鼠 RASD1 RASD1 19416 O35626
大鼠 RASD1 RASD1 64455 Q9JKF8
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB Mouse liver lysates probed with Rabbit Anti-RASD1 Polyclonal Antibody, Unconjugated (ABIN2559449) at 1:300 in 4˚C. Followed by conjugation to secondary antibody at 1:5000 for 90min at 37˚C. 100 μL Log in to see 3至7个工作日
小鼠 非结合性 IHC (p), WB Western blot analysis in mouse liver tissue lysates (35ug/lane). RASD1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 2至3个工作日
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: Dexras1 Antibody [NBP1-91830] - Staining of human stomach, upper shows strong cytoplasmic and nuclear positivity in glandular cells. Western Blot: Dexras1 Antibody [NBP1-91830] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY414190) 0.1 mL Log in to see 10至13个工作日
HRP WB   100 μL Log in to see 14至21个工作日
Biotin WB   100 μL Log in to see 14至21个工作日
小鼠 非结合性 IF, ELISA Immunofluorescence of monoclonal antibody to RASD1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 11至12个工作日
小鼠 非结合性 IHC, ELISA, WB   200 μL Log in to see 11至16个工作日
小鼠 Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
小鼠 HRP IHC, ELISA, WB   200 μL Log in to see 7至9个工作日
小鼠 FITC IHC, ELISA, WB   200 μL Log in to see 7至9个工作日


Human RAS, Dexamethasone-Induced 1 (RASD1) interaction partners

  1. Studies indicate potential roles for Rasd1 small G protein (显示 RAC2 抗体) and leptin (显示 LEP 抗体) in TRPC4 (显示 TRPC4 抗体) cation channel (显示 TRPV1 抗体) activation.

  2. Data indicate that protein kinase A (PKA) phosphorylates only serine-253 amino acid on activator of G-protein signaling 1 protein Dexras1 (RASD1).

  3. Loss of RASD1 is associated with prostate cancer.

  4. Study showed that Rasd1 and NonO (显示 NONO 抗体) interact at the CRE-site of specific target genes.

  5. Rasd1 modulates endogenous renin (显示 REN 抗体) gene expression by interacting with Ear2 (显示 NR2F6 抗体).

  6. A glucocorticoid response element (GRE) was identified in the 3'-flanking region (2.3 kb downstream of poly(A) signal) of the human Dexras1 gene. A point mutation within the 15-bp GRE abolished this glucocorticoid responsiveness

  7. yeast two hybrid analysis and co-immunoprecipitation studies in mammalian cells demonstrate a direct interaction between AGS1 (显示 TREX1 抗体) and the G(beta1) subunit of heterotrimeric G proteins

  8. does not alter the membrane translocation of protein kinase C delta (显示 PKCd 抗体).

  9. Dexras1 plays a critical role in shaping the photic phase response curve (PRC (显示 PPRC1 抗体)) and the signaling events through which it regulates clock entrainment in transgenic mice.

  10. dex-ras1 mRNA is not induced by glucocorticoid stimulation in HEK293 cells

Mouse (Murine) RAS, Dexamethasone-Induced 1 (RASD1) interaction partners

  1. These results suggest that Dexras1 is a critical mediator of the IGF-1 (显示 IGF1 抗体) signal to activate MAPK (显示 MAPK1 抗体), linking glucocorticoid signaling to IGF-1 (显示 IGF1 抗体) signaling in adipogenesis.

  2. These findings suggest that RASD1 acts as a novel signaling molecule and plays an important role in regulating dynamic uterine remodeling during the estrous cycle in the uterus.

  3. This study demonstrated that provide unprecedented evidence for a selective epigenetic up-regulation of Dexras 1 gene expression in the striatum of EAE mice.

  4. RASD1 is a novel factor in Metaphase I-Metaphase II oocyte transition and may be involved in regulating the progression of cytokinesis and spindle formation

  5. Results suggest a potential role for Dexras1 in modulating a selective subset of psychiatric symptoms, possibly via its interaction with NMDARs and/or other disease-related binding-partners

  6. two mechanisms of Rasd1 induction in the hypothalamus, were identified.

  7. Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase (显示 RACGAP1 抗体), Dexras1

  8. Dexras1 mediates adipogenesis and diet-induced obesity.

  9. Dexras1 is involved in the circadian clock regulation

  10. Dexras1 appears to mediate N-methylaspartate (NMDA)-elicited neurotoxicity via nitric oxide and iron influx.

RASD1 抗原简介


This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RASD1

  • ras related dexamethasone induced 1 (RASD1) 抗体
  • RAS, dexamethasone-induced 1 (Rasd1) 抗体
  • ras related dexamethasone induced 1 (Rasd1) 抗体
  • AGS1 抗体
  • Dexras1 抗体
  • MGC:26290 抗体

Protein level used designations for RASD1

activator of G-protein signaling 1 , dexamethasone-induced Ras-related protein 1 , ras-related protein , DEXRAS1 (Dexras1)

51655 Homo sapiens
19416 Mus musculus
64455 Rattus norvegicus