RAD17 Homolog (S. Pombe) 蛋白
The protein encoded by RAD17 is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage.
Recommended next Filters:
4 results:
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-681) protein (His tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-688) protein (His tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-584) protein (GST tag) Protein
RAD17 Homolog (S. Pombe) (RAD17) (AA 1-110) protein (GST tag) Protein
蛋白简介RAD17 Homolog (S. Pombe) (RAD17)
蛋白简介
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Eight alternatively spliced transcript variants of this gene, which encode four distinct proteins, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified.
Gene names and symbols associated with RAD17 Homolog (S. Pombe) 蛋白 (RAD17)
- RAD17 checkpoint clamp loader component (RAD17) 抗体
- RAD17 checkpoint clamp loader component (rad17) 抗体
- Rad17p (RAD17) 抗体
- RADIATION SENSITIVE 17 (ATRAD17) 抗体
- RAD17 checkpoint clamp loader component (Rad17) 抗体
- 9430035O09Rik 抗体
- CCYC 抗体
- HRAD17 抗体
- K2A18.21 抗体
- K2A18_21 抗体
- MmRad24 抗体
- R24L 抗体
- RAD17 抗体
- RAD17SP 抗体
- RAD24 抗体
- RADIATION SENSITIVE 17 抗体
- zgc:91969 抗体
Protein level used designations for RAD17 Homolog (S. Pombe) 蛋白 (RAD17)
RAD17 homolog (S. pombe) , cell cycle checkpoint protein RAD17-like , cell cycle checkpoint protein RAD17 , Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins , Rad17p , RAD17 homolog , Cell cycle checkpoint protein RAD17 , RAD1 homolog , RF-C activator 1 homolog , RF-C/activator 1 homolog , Rad17-like protein , cell cycle checkpoint protein (RAD17)
GENE ID | SPECIES |
---|---|
100081629 | Ornithorhynchus anatinus |
100339735 | Oryctolagus cuniculus |
100385537 | Callithrix jacchus |
100464145 | Ailuropoda melanoleuca |
436934 | Danio rerio |
854550 | Saccharomyces cerevisiae S288c |
100190842 | Pongo abelii |
836745 | Arabidopsis thaliana |
5884 | Homo sapiens |
19356 | Mus musculus |
478088 | Canis lupus familiaris |
513600 | Bos taurus |
310034 | Rattus norvegicus |
100065769 | Equus caballus |