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PDHX 抗体

(Pyruvate Dehydrogenase Complex, Component X (PDHX))
The pyruvate dehydrogenase (PDH) complex is located in the mitochondrial matrix and catalyzes the conversion of pyruvate to acetyl coenzyme A. The PDH complex thereby links glycolysis to Krebs cycle. The PDH complex contains three catalytic subunits, E1, E2, and E3, two regulatory subunits, E1 kinase and E1 phosphatase, and a non-catalytic subunit, E3 binding protein (E3BP). This gene encodes the E3 binding protein subunit\; also known as component X of the pyruvate dehydrogenase complex. This protein tethers E3 dimers to the E2 core of the PDH complex. Defects in this gene are a cause of pyruvate dehydrogenase deficiency which results in neurological dysfunction and lactic acidosis in infancy and early childhood. This protein is also a minor antigen for antimitochondrial antibodies. These autoantibodies are present in nearly 95% of patients with the autoimmune liver disease primary biliary cirrhosis (PBC). In PBC, activated T lymphocytes attack and destroy epithelial cells in the bile duct where this protein is abnormally distributed and overexpressed. PBC eventually leads to cirrhosis and liver failure. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2009].
PDHX 抗体  (AA 220-468) PDHX 抗体  (AA 220-468) PDHX 抗体 (AA 220-468) (ABIN7443305)

PDHX 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PDHX 抗体  (AA 222-471) PDHX 抗体  (AA 222-471) PDHX 抗体 (AA 222-471) (ABIN7443338)

PDHX 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PDHX 抗体  (AA 1-300) PDHX 抗体  (AA 1-300) PDHX 抗体 (AA 1-300) (ABIN7166903)

PDHX 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

PDHX 抗体 by Grade

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PDHX 抗体 by 适用

Find PDHX 抗体 for a variety of species such as anti-Human PDHX, anti-Mouse PDHX, anti-Rat PDHX. The species listed below are among those available. Click on a link to go to the corresponding products.

PDHX 抗体 by 应用范围

Find PDHX 抗体 validated for a specific application such as WB, IF (cc), IF (p), IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

PDHX 抗体 by 抗体来源

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PDHX 抗体 by 抗原表位

Find PDHX 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PDHX 抗体 by 克隆形成能力

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PDHX 抗体 by 克隆

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PDHX 抗体 by 标记

Find PDHX 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PDHX 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7443305
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7443338
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (4)
Cat. No. ABIN7166903
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN521742
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN544818
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (3)
Cat. No. ABIN948658
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN563534
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (2)
Cat. No. ABIN544819
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN185389
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN6145384
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p), EIA
Validations
  • (3)
Cat. No. ABIN357414
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IF
Validations
  • (1)
Cat. No. ABIN7262258
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN2856340
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IC
Validations
  • (2)
Cat. No. ABIN7306614
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
Cat. No. ABIN708221
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PDHX 抗体

Schild, Ruhs, Beiter, Zügel, Hudemann, Reimer, Krumholz-Wagner, Wagner, Keller, Eder, Krüger, Krüger, Braun, Nieß, Steinacker, Mooren: "Basal and exercise induced label-free quantitative protein profiling of m. vastus lateralis in trained and untrained individuals." in: Journal of proteomics, Vol. 122, pp. 119-32, (2015) (PubMed).

Murray, Gilkerson, Capaldi: "Quantitative proteomics: the copy number of pyruvate dehydrogenase is more than 10(2)-fold lower than that of complex III in human mitochondria." in: FEBS letters, Vol. 529, Issue 2-3, pp. 173-8, (2002) (PubMed).

Roche, Baker, Yan, Hiromasa, Gong, Peng, Dong, Turkan, Kasten: "Distinct regulatory properties of pyruvate dehydrogenase kinase and phosphatase isoforms." in: Progress in nucleic acid research and molecular biology, Vol. 70, pp. 33-75, (2001) (PubMed).

Aliases for PDHX 抗体

pyruvate dehydrogenase complex component X (PDHX) 抗体
pyruvate dehydrogenase complex, component X (Pdhx) 抗体
pyruvate dehydrogenase complex, component X (pdhx) 抗体
pyruvate dehydrogenase complex component X L homeolog (pdhx.L) 抗体
E3-binding protein (pdhX) 抗体
pyruvate dehydrogenase complex component X (pdhx) 抗体
Ac1164 抗体
AI481367 抗体
DDBDRAFT_0168431 抗体
DDBDRAFT_0230192 抗体
DDB_0168431 抗体
DDB_0230192 抗体
DLDBP 抗体
E3BP 抗体
E3bp 抗体
MGC86218 抗体
OPDX 抗体
PDHX 抗体
PDX1 抗体
Pdx1 抗体
proX 抗体
zgc:66110 抗体
zgc:85977 抗体
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