PPP4C 蛋白
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Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 2-307) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 2-307) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) 蛋白 Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 218-307) protein (GST tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) protein (GST tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 2-307) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 2-307) protein (His tag) Protein
Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 2-307) protein (His tag) Protein
蛋白简介PPP4C
蛋白简介
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C- PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin.
Gene names and symbols associated with PPP4C
- protein phosphatase 4 catalytic subunit (ppp4c) 抗体
- protein phosphatase 4, catalytic subunit a (ppp4ca) 抗体
- protein phosphatase 4 catalytic subunit (PPP4C) 抗体
- protein phosphatase 4, catalytic subunit (Ppp4c) 抗体
- protein phosphatase 4 catalytic subunit S homeolog (ppp4c.S) 抗体
- 1110002D08Rik 抗体
- AU016079 抗体
- gc:56413 抗体
- MGC75928 抗体
- PP4 抗体
- PP4C 抗体
- PP4C-A 抗体
- PPH3 抗体
- PPP4 抗体
- ppp4c 抗体
- Ppx 抗体
- wu:fd05e08 抗体
- zgc:56413 抗体
Protein level used designations for PPP4C
protein phosphatase 4, catalytic subunit , catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit A , PP-X , protein phosphatase 4 (formerly X), catalytic subunit , protein phosphatase X, catalytic subunit , serine/threonine-protein phosphatase 4 catalytic subunit , PP4C , pp4 , protein phosphatase X
| GENE ID | SPECIES |
|---|---|
| 394540 | Xenopus (Silurana) tropicalis |
| 100003080 | Danio rerio |
| 5531 | Homo sapiens |
| 540398 | Bos taurus |
| 56420 | Mus musculus |
| 171366 | Rattus norvegicus |
| 489947 | Canis lupus familiaris |
| 100009163 | Oryctolagus cuniculus |
| 432334 | Xenopus laevis |
| 100173513 | Pongo abelii |
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