Protein Kinase N1 (PKN1) ELISA试剂盒

The protein encoded by PKN1 belongs to the protein kinase C superfamily. 再加上,我们可以发PKN1 抗体 (43)PKN1 蛋白 (11)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
PKN1 5585 Q16512
PKN1 320795 P70268
PKN1 29355 Q63433
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.117 ng/mL 0.31 ng/mL - 20 ng/mL   96 Tests Log in to see 13至16个工作日
$663.16
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小鼠 0.938 ng/mL 1.563-100 ng/mL Typical standard curve 96 Tests Log in to see 12至14个工作日
$630.00
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大鼠 0.938 ng/mL 1.563-100 ng/mL Typical standard curve 96 Tests Log in to see 12至14个工作日
$638.00
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Pig 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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小鸡 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12至14个工作日
$715.00
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豚鼠
  96 Tests Log in to see 15至18个工作日
$707.14
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绵羊
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  96 Tests Log in to see 15至18个工作日
$707.14
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适于 PKN1 相互作用对的更多 ELISA 试剂盒

Human Protein Kinase N1 (PKN1) interaction partners

  1. Steady-state kinetic analysis revealed that PKN1-3 follows a sequential ordered Bi-Bi (显示 CACNA1A ELISA试剂盒) kinetic mechanism, where peptide substrate binding is preceded by ATP binding. This kinetic mechanism was confirmed by additional kinetic studies for product inhibition and affinity of small molecule inhibitors.

  2. Pkn1 is not required for tumorigenesis initiated by loss of Pten. Triple knockout of Pten, Pkn1, and Pkn2 in mouse prostate results in squamous cell carcinoma, an uncommon but therapy-resistant form of prostate cancer.

  3. PKN1 activity was up-regulated by the active RhoA (显示 RHOA ELISA试剂盒) mutant (G14V) and suppressed by RhoA (显示 RHOA ELISA试剂盒) T19N. PKN1 siRNA interrupted the ability of RhoA (显示 RHOA ELISA试剂盒) to promote ESC proliferation and DNA synthesis. The effect of RhoA (显示 RHOA ELISA试剂盒) on ESC proliferation is mediated by activation of the PKN1-cyclin D1 (显示 CCND1 ELISA试剂盒) pathway in vitro.

  4. TXA2-mediated neoplastic responses in prostate adenocarcinoma PC-3 cells occur through a PRK1/PRK2-dependent mechanism.

  5. Transcriptome and interactome analyses uncover that PRK1 regulates expression of migration-relevant genes by interacting with the scaffold protein (显示 HOMER1 ELISA试剂盒) sperm-associated antigen 9 (SPAG9/JIP4 (显示 SPAG9 ELISA试剂盒)).

  6. Data indicate that Salmonella SspH1 catalyzes the ubiquitination and proteasome-dependent degradation of PKN1 in cells.

  7. Protein kinase N1 inhibits Wnt/b-catenin signaling and apoptosis in melanoma cells.

  8. Protein kinase N1 is a novel substrate of NFATc1 (显示 NFATC1 ELISA试剂盒)-mediated cyclin D1 (显示 CCND1 ELISA试剂盒)-CDK6 (显示 CDK6 ELISA试剂盒) activity and modulates vascular smooth muscle cell division and migration leading to inward blood vessel wall remodeling.

  9. PKN isoforms are not simply redundant in supporting migration, but appear to be linked through isoform specific regulatory domain properties to selective upstream signals. It

  10. Data show that just one contact site as being relevant for binding of RhoA (显示 RHOA ELISA试剂盒) and domain from PRK1, and the HR1b domain was found not to contribute to RhoA (显示 RHOA ELISA试剂盒) binding.

Mouse (Murine) Protein Kinase N1 (PKN1) interaction partners

  1. In mice, phosphorylation-regulated (显示 PHAX ELISA试剂盒) neutrophil polarization mechanism is driven by PKN1-mediated phosphorylation of a newly identified RAB21 effector RPH3A (显示 RPH3A ELISA试剂盒).

  2. Pkn1 is not required for tumorigenesis initiated by loss of Pten. Triple knockout of Pten, Pkn1, and Pkn2 in mouse prostate results in squamous cell carcinoma, an uncommon but therapy-resistant form of prostate cancer.

  3. Mechanistically, Yersinia pseudotuberculosis YopM recruits and activates the mouse host kinases PRK1 and PRK2 to negatively regulate pyrin (显示 MEFV ELISA试剂盒) by phosphorylation.

  4. Protein kinase N1, a cell inhibitor of Akt (显示 AKT1 ELISA试剂盒) kinase, has a central role in quality control of germinal center formation

  5. PKN is activated by ischemia/reperfusion and inhibits apoptosis of cardiac myocytes, thereby protecting the heart from I/R injury.

  6. Leishmania mexicana infectivity is associated with differential expression of protein kinase C (显示 PKC ELISA试剂盒)-like triggered during a cell-cell contact

  7. Pkn1 is involved in ganglioside signals that regulate TNF-alpha (显示 TNF ELISA试剂盒) signaling and synthesis.

Fruit Fly (Drosophila melanogaster) Protein Kinase N1 (PKN1) interaction partners

  1. polarity-induced spatiotemporal control of Rok (显示 ROCK1 ELISA试剂盒) and Pkn is important for unequal cortical expansion, ensuring correct cleavage furrow positioning and the establishment of physical asymmetry.

  2. The delorean phenotype, with its associated defects in wing morphology, provides evidence of a role for PKN in adult morphogenetic processes.

  3. Drosophila protein kinase N is a negative regulator of actin-myosin activity during oogenesis.

  4. identified a requirement for Pkn in wing morphogenesis, thereby revealing the first postembryonic function for Pkn

PKN1 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Gene names and symbols associated with Protein Kinase N1 (PKN1) ELISA试剂盒

  • protein kinase N1 (PKN1) 抗体
  • protein kinase N1 (Pkn1) 抗体
  • protein kinase N1b (pkn1b) 抗体
  • protein kinase N1 (pkn1) 抗体
  • Protein kinase N (Pkn) 抗体
  • 3-2 抗体
  • CG2049 抗体
  • CG2055 抗体
  • CT6637 抗体
  • CT6660 抗体
  • DBK 抗体
  • Dmel\\CG2049 抗体
  • dPKN 抗体
  • F730027O18Rik 抗体
  • l(2)06736 抗体
  • l(2)45Ca 抗体
  • PAK-1 抗体
  • PAK1 抗体
  • Pk45C 抗体
  • Pk?3 抗体
  • Pkn 抗体
  • PKN-ALPHA 抗体
  • PKN1 抗体
  • PRK1 抗体
  • PRK2 抗体
  • Prkcl1 抗体
  • Stk3 抗体
  • v(2)rG232 抗体

Protein level used designations for Protein Kinase N1 (PKN1) ELISA试剂盒

protease-activated kinase 1 , protein kinase C-like 1 , protein kinase C-like PKN , protein kinase C-related kinase 1 , protein kinase PKN-alpha , protein-kinase C-related kinase 1 , serine-threonine kinase N , serine-threonine protein kinase N , serine/threonine protein kinase N , serine/threonine-protein kinase N1 , serine/threonine kinase 3 , protein kinase N1 , serine/threonine-protein kinase N1-like , protein kinase PKN , CG2049-PB , CG2049-PC , CG2049-PD , CG2049-PE , CG2049-PF , CG2049-PG , CG2049-PH , CG2049-PI , CG2049-PJ , CG2049-PK , CG2049-PL , CG2049-PM , Pkn-PB , Pkn-PC , Pkn-PD , Pkn-PE , Pkn-PF , Pkn-PG , Pkn-PH , Pkn-PI , Pkn-PJ , Pkn-PK , Pkn-PL , Pkn-PM , protein kinase N , protein kinase c related , protein kinase related to protein kinase N , protein kinase-like 45C

GENE ID SPECIES
5585 Homo sapiens
320795 Mus musculus
455785 Pan troglodytes
509080 Bos taurus
100007897 Danio rerio
100379847 Xenopus (Silurana) tropicalis
100401855 Callithrix jacchus
29355 Rattus norvegicus
35950 Drosophila melanogaster
100713234 Cavia porcellus
101118101 Ovis aries
100856398 Canis lupus familiaris
100515528 Sus scrofa
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