Prostate Tumor Overexpressed 1 蛋白 (PTOV1)

Mouse (Murine) Prostate Tumor Overexpressed 1 (PTOV1) interaction partners

1. PTOV1 is associated with UCH-L1 (显示 UCHL1 蛋白) and in response to estrogen stimuli during the mouse oocyte development

Human Prostate Tumor Overexpressed 1 (PTOV1) interaction partners

1. The combination of PTOV1 expression level and HPV status provides more prognostic information compared with HPV status alone in early-stage human laryngeal squamous cell carcinoma.

2. Studies indicate that the number of binding partners and associated cellular functions has increased and helped to identify prostate-tumor-overexpressed-1 (PTOV1) as regulator of gene expression at transcription and translation levels.

3. this study takes the lead to demonstrate that the overexpressed PTOV1 plays a vital role in the tumorigenesis and progression of esophageal squamous cell carcinoma, and it is potentially a valuable prognostic predicator and new chemotherapeutic target for esophageal squamous cell carcinoma

4. All the study samples showed a considerable decrease in PTOV1 expression in prostate cancer and HGPIN compared to morphologically normal glands.

5. High PTOV1 expression was associated with invasive urothelial carcinoma.

6. PTOV1 overexpression is associated with poor survival outcomes of nasopharyngeal carcinoma patients.

7. PTOV1 protein abnormal expression might contribute to the malignant progression of epithelial ovarian cancer.

8. Our study demonstrated that PTOV1 overexpression is correlated with increased aggressiveness of hepatocellular carcinoma and could be a prognostic biomarker for patients with HCC (显示 FAM126A 蛋白)

9. The study showed that PTOV1 is upregulated in breast cancer cell lines and clinical samples, and its expression was positively associated with progression and aggressiveness of breast cancer, suggesting that PTOV1 could serve as an independent prognostic marker.

10. In prostate tumors, the overexpression of PTOV1 was associated with decreased expression of HEY1 (显示 HEY1 蛋白) and HES1 (显示 HES1 蛋白), and this correlation was significant in metastatic lesions.