蛋白简介

This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with PEX19

• Peroxin 19 (Pex19) 抗体
• Peroxisomal farnesylated protein (Bm1_19905) 抗体
• peroxisomal biogenesis factor 19 (PEX19) 抗体
• peroxisomal biogenesis factor 19 (Pex19) 抗体

• BEST:GH03076 抗体
• CG5325 抗体
• D1S2223E 抗体
• DmelPex19 抗体
• Dmel\\CG5325 抗体
• 显示所有的同义词和别名
• HK33 抗体
• PBD12A 抗体
• Peroxin-19 抗体
• PMP1 抗体
• PMPI 抗体
• PxF 抗体
• PXMP1 抗体

Protein level used designations for PEX19

CG5325-PA , CG5325-PB , Pex19-PA , Pex19-PB , peroxin 19 , peroxisomal farnesylated protein , Peroxisomal farnesylated protein , 33 kDa housekeeping protein , housekeeping gene, 33kD , peroxin-19 , peroxisome biogenesis factor 19