anti-PAP Associated Domain Containing 4 (PAPD4) 抗体

Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. 再加上,我们可以发PAP Associated Domain Containing 4 试剂盒 (7)PAP Associated Domain Containing 4 蛋白 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
PAPD4 167153 Q6PIY7
PAPD4 100715 Q91YI6
PAPD4 361878 Q5U315
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antibodies-online.cn销售最多的anti-PAP Associated Domain Containing 4 抗体

Showing 10 out of 31 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-PAPD4 Antibody Titration:  0.2-1 ug/ml  Positive Control:  MCF7 cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-Papd4 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:12500  Positive Control:  Rat Kidney 100 μL Log in to see 2至3个工作日
$289.00
详细
Hamster 非结合性 IHC (p), WB (LEFT)Western blot analysis of GLD2 Antibody (N-term) (ABIN651284) in MCF-7 cell line lysates (35 µg/lane).GLD2 (arrow) was detected using the purified polyclonal antibody. (MIDDLE)Western blot analysis of GLD2 Antibody (N-term) (ABIN651284) in mouse heart tissue lysates (35 µg/lane).GLD2 (arrow) was detected using the purified polyclonal antibody. (RIGHT)Western blot analysis of GLD2 Antibody (N-term) (ABIN651284) in CHO cell line lysates (35 µg/lane).GLD2 (arrow) was detected using the purified polyclonal antibody. GLD2 Antibody (N-term) (ABIN651284) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
$385.00
详细
Bat 非结合性 WB 100 μL Log in to see 11至14个工作日
$551.83
详细
Bat 非结合性 WB 100 μL Log in to see 11至14个工作日
$551.83
详细
非结合性 IF, IHC (p), WB Fluorescent image of MCF-7 cells stained with GLD2 Antibody (N-term). AP5092a was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red). Immunohistochemical analysis of paraffin-embedded H. cerebellum section using GLD2 Antibody (N-term). Antibody was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining. 400 μL Log in to see 2至3个工作日
$515.63
详细
非结合性 WB Western blot analysis of extracts of various cell lines, using PAPD4 antibody. 200 μL Log in to see 12至14个工作日
$438.90
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非结合性 WB PAPD4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细
非结合性 WB Papd4 antibody used at 0.2-1 ug/ml to detect target protein. 50 μg Log in to see 9至11个工作日
$473.93
详细
Hamster Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 11至14个工作日
$1,101.83
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引用最多的anti-PAP Associated Domain Containing 4 抗体

  1. Cow (Bovine) Polyclonal PAPD4 Primary Antibody for WB - ABIN2783643 : Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France. in Diagnostic microbiology and infectious disease 2006 (PubMed)
    Show all 2 Pubmed References

  2. Hamster Polyclonal PAPD4 Primary Antibody for IHC (p), WB - ABIN651284 : Mullen, Marzluff: Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'. in Genes & development 2008 (PubMed)
    Show all 3 Pubmed References

更多抗PAP Associated Domain Containing 4的相互作用对抗体

Human PAP Associated Domain Containing 4 (PAPD4) interaction partners

  1. our results propose a novel feedback regulatory mechanism for controlling HCV RNA abundance by the viral capsid protein, which is capable of modulating miR-122 activity and stability through the inhibition of GLD-2.

  2. QKI-7 recruits PAPD4 to regulate post-transcriptional polyadenylation of target mRNAs.

  3. HBx is a critical protein derived from HBV, which regulates miR-122 via down-regulating Gld2

  4. The noncanonical polymerase Gld2 has been implicated in the stabilization of miR-122, possibly through catalyzing 3' monoadenylation

  5. Study identified TUT7, TUT4, and TUT2 as novel components of the miRNA biogenesis pathway.

  6. poly(A) polymerase Gld2, deadenylase PARN, and translation inhibitory factor neuroguidin (Ngd) are components of a dendritic CPEB-associated polyadenylation apparatus

  7. human CPE-binding protein 1 and hGLD-2 are antagonizing factors regulating p53 mRNA stability.

  8. The authors show that the human CPEB1 can repress the activity of the reporter construct containing the HPV-16 early sequences. This repression can be counteracted by a human cytoplasmic poly(A) polymerase, hGLD-2 fused to CPEB1.

Mouse (Murine) PAP Associated Domain Containing 4 (PAPD4) interaction partners

  1. In Gld2 knockout mice there are detectable alterations in specific miRNA monoadenylation in the hippocampus, but no detectable effect on miRNA stability and no overt change in animal behavior.

  2. poly(A) polymerase Gld2, deadenylase PARN, and translation inhibitory factor neuroguidin (Ngd) are components of a dendritic CPEB-associated polyadenylation apparatus

  3. We found an association of mGLD-2 with cytoplasmic polyadenylation components, CPEB and CPSF described in Xenopus oocytes

  4. mGLD-2 may act in the ooplasm on the progression of metaphase I to metaphase II during oocyte maturation.

  5. identified GLD-2, which is a regulatory cytoplasmic poly(A) polymerase, as responsible for the 3'-terminal adenylation of miR-122 after unwinding of the miR-122/miR-122* duplex

Caenorhabditis elegans (C. elegans) PAP Associated Domain Containing 4 (PAPD4) interaction partners

  1. investigate whether the functions of the cytoplasmic poly(A) polymerase (cytoPAP) GLD-2 in C. elegans germ cells exclusively depend on its catalytic activity; findings highlight the enzymatic importance of noncanonical poly(A) polymerases and emphasize the pivotal role of poly(A) tail-centered cytoplasmic mRNA regulation in germ cell biology.

  2. GLD-2 thus appears to have evolved specialized nucleotidyl-transferase properties that match the 3' end features of dormant cytoplasmic mRNAs

  3. The analyses suggest that GLD-2 activity mediates mRNA stability of many translationally repressed mRNAs.

  4. Data suggest that the FBF-2/GLD-2 protein directed polyadenylation of the endogenous mRNA, compensating for that mRNA's natural deadenylation.

  5. Data suggest that the GLD-2/RNP-8 enzyme is a broad-spectrum regulator of the oogenesis program that acts within an RNA regulatory network to specify and produce fully functional oocytes.

  6. Regulates Gld-1 messenger RNA in germ cells, enabling the transition from mitosis to meiosis.

  7. FBF can affect polyadenylation either negatively by its CCF-1 interaction or positively by its GLD-2 interaction in control of GLD1 expression.

  8. GLD-4 is predominantly expressed in germ cells, and its activity is essential for early meiotic progression of male and female gametes in the absence of GLD-2

  9. In C. elegans hermaphrodites, gamete production begins with spermatogenesis and transitions later to oogenesis; the combinatorial use of GLD-2 contributes to this transition, as GLD-2/GLD-3 promotes spermatogenesis, and GLD-2/RNP-8 specifies oogenesis.

PAP Associated Domain Containing 4 (PAPD4) 抗原简介

蛋白简介

Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. Acts as a regulator of mitosis/meiosis required for progression through meiotic prophase during oogenesis and spermatogenesis and for promotion of the entry into meiosis from the mitotic cell cycle. May act by regulating and activating gld-1 mRNA activity in germ line.

Gene names and symbols associated with PAPD4

  • poly(A) RNA polymerase D4, non-canonical (PAPD4) 抗体
  • PAP associated domain containing 4 (Papd4) 抗体
  • poly(A) RNA polymerase D4, non-canonical (Papd4) 抗体
  • PAP associated domain containing 4 (papd4) 抗体
  • Poly(A) RNA polymerase gld-2 (gld-2) 抗体
  • 8030446C20Rik 抗体
  • AI649009 抗体
  • GLD-2 抗体
  • Gld2 抗体
  • zgc:110560 抗体

Protein level used designations for PAPD4

PAP-associated domain-containing protein 4 , TUTase 2 , hGLD-2 , poly(A) RNA polymerase GLD2 , terminal uridylyltransferase 2 , cytoplasmic poly(A) polymerase , mGLD-2 , TUTase2

GENE ID SPECIES
167153 Homo sapiens
607764 Canis lupus familiaris
533862 Bos taurus
100715 Mus musculus
361878 Rattus norvegicus
553626 Danio rerio
172338 Caenorhabditis elegans
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