anti-Nuclear Transcription Factor, X-Box Binding 1 (NFX1) 抗体

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes.

列出全部抗体 基因 基因ID UniProt
 NFX1 NFX1 4799 Q12986
小鼠 NFX1 NFX1 74164 B1AY10
大鼠 NFX1 NFX1 313166  
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Showing 10 out of 41 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-NFX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate NFX1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, WB WB Suggested Anti-NFX1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  HepG2 cell lysate Immunohistochemistry with Human Testis lysate tissue 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with NFX1 antibody ABIN462262 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with NFX1 antibody ABIN462262 followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
$727.83
详细
非结合性 WB 50 μg Log in to see 7至9个工作日
$551.83
详细
小鼠 非结合性 IF, ELISA, WB NFX1 monoclonal antibody (M01), clone 1D12 Western Blot analysis of NFX1 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to NFX1 on HeLa cell. [antibody concentration 30 ug/ml] 100 μg Log in to see 11至12个工作日
$440.00
详细
非结合性 IP, WB Western Blot: NFX1 Antibody [NBP1-49933] - Detection of Human and Mouse NFX1 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg) and mouse NIH3T3 (M; 50 mcg) cells. Antibodies: Affinity purified rabbit anti-NFX1 antibody used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate. NFX1 was also immunoprecipitated by rabbit anti-NFX1 antibodies which recognize upstream epitopes. For blotting immunoprecipitated NFX1 was used. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 7至9个工作日
$556.31
详细
小鼠 非结合性 IF, WB Immunofluorescence of monoclonal antibody to NFX1 on HeLa cell (antibody concentration 30 µg/mL). NFX1 monoclonal antibody (M01), clone 1D12 Western Blot analysis of NFX1 expression in HeLa NE. 0.1 mg Log in to see 8至11个工作日
$450.00
详细
非结合性 ELISA, WB 50 μg Log in to see 2至3个工作日
$446.88
详细
小鼠 非结合性 IF, ELISA, WB   100 μg Log in to see 7至9个工作日
$537.17
详细
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 11至12个工作日
$305.71
详细

更多抗Nuclear Transcription Factor, X-Box Binding 1的相互作用对抗体

Human Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. This study identifies NFX1-123 as a critical host protein partner through which 16E6 is able to subvert the immune response and in turn permit a long-lived high-risk Human papillomavirus infection.

  2. The results showed that a repressor complex composed of NFX1-91, mSin3A and histone deacetylase 1 (显示 HDAC1 抗体) was involved in the PKC-delta (显示 PKCd 抗体)-induced repression of the hTERT promoter, which resulted in the repression of hTERT transcription.

  3. Human papillomavirus 16 E6 (16E6) interacts with the cellular protein NFX1-123, and they collaboratively increase the growth and differentiation master regulator, Notch1 (显示 NOTCH1 抗体).

  4. NFX1-123 and human papillomavirus 16E6 upregulated Notch 1 (显示 NOTCH1 抗体) expression in keratinocytes.

  5. a mechanism for HPV16 E6 activation of the NFkappaB (显示 NFKB1 抗体) pathway through NFX1-91

  6. HuD (显示 ELAVL4 抗体) acts as a novel adaptor protein to recruit TAP for efficient export of ARE-containing mRNAs in neuronal cells

  7. the induction of hTERT telomerase by the HPV-16 E6/E6-AP (显示 ube3a 抗体) complex involves targeting of NFX1-91, a newly identified repressor of telomerase, for ubiquitination and degradation.

  8. Nrf1 (显示 NFE2L1 抗体) is normally targeted to the endoplasmic reticulum membrane and endoplasmic reticulum stress may play a role in modulating Nrf1 (显示 NFE2L1 抗体) function as a transcriptional activator

  9. data suggest that NFX1-123 is integral to hTERT regulation in HPV16 E6-expressing epithelial cells and that the interaction between NFX1-123 and poly(A) binding proteins is critical to hTERT activity

  10. These data demonstrate that targeted degradation of NFX1-91 by E6/E6AP (显示 ube3a 抗体) dissociates the mSin3A/HDAC (显示 HDAC3 抗体) complex from the hTERT promoter and induces hTERT transcription.

Mouse (Murine) Nuclear Transcription Factor, X-Box Binding 1 (NFX1) interaction partners

  1. Mutation E610G, quantitatively accounts for the Nxf1 (显示 NXF1 抗体) modifier gene activity toward IAP (显示 ALPI 抗体) insertion.

  2. nuclear accumulation and modulation of unfolded protein response regulated by subunit of phosphoinositide 3-kinase

  3. nuclear translocation regulated by p85alpha and p85beta monomers of PI3K

Nuclear Transcription Factor, X-Box Binding 1 (NFX1) 抗原简介

蛋白简介

MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN-gamma. Three alternative splice variants, each of which encodes a different isoform, have been identified.

Gene names and symbols associated with NFX1

  • nuclear transcription factor, X-box binding 1 (NFX1) 抗体
  • nuclear transcription factor, x-box binding 1 (CpipJ_CPIJ011986) 抗体
  • nuclear transcription factor, X-box binding 1 (nfx1) 抗体
  • nuclear transcription factor, X-box binding 1 (Nfx1) 抗体
  • 1300017N15Rik 抗体
  • 3000003M19Rik 抗体
  • NFX.1 抗体
  • NFX1 抗体
  • NFX2 抗体
  • TEG-42 抗体
  • Tex42 抗体

Protein level used designations for NFX1

nuclear transcription factor, X-box binding 1 , nuclear transcription factor, x-box binding 1 , transcriptional repressor NF-X1-like , nuclear transcription factor, X box-binding protein 1 , transcriptional repressor NF-X1 , m-Nfx.1 , nuclear X box binding factor 1 , testis expressed gene 42

GENE ID SPECIES
420796 Gallus gallus
465042 Pan troglodytes
6044908 Culex quinquefasciatus
100009971 Monodelphis domestica
100399247 Callithrix jacchus
100488254 Xenopus (Silurana) tropicalis
100590740 Nomascus leucogenys
4799 Homo sapiens
481581 Canis lupus familiaris
515680 Bos taurus
74164 Mus musculus
313166 Rattus norvegicus
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