蛋白简介

This gene encodes a member of the nucleotide-binding oligomerization domain/ leucine rich repeat/ pyrin domain containing (NLRP) subfamily, which belongs to the Nod-like receptor family of proteins. NLRP genes play roles in the mammalian innate immune system through inflammasome formation and activation of caspases. In addition, NLRP genes have been found to function during mammalian reproduction. Consistent with a function during human preimplantation development, this gene is expressed at high levels in oocytes with decreased levels in embryos. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with NLRP8

• NLR family pyrin domain containing 8 (NLRP8) 抗体

• CLR19.2 抗体
• NALP8 抗体
• NOD16 抗体
• PAN4 抗体

Protein level used designations for NLRP8

NACHT, LRR and PYD containing protein 8 , NACHT, LRR and PYD domains-containing protein 8 , NACHT, leucine rich repeat and PYD containing 8 , PYRIN and NACHT-containing protein 4 , nucleotide-binding oligomerization domain protein 16 , nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8 , NLR family, pyrin domain containing 8 , NLR family pyrin domain-containing protein 8