Mucin 16, Cell Surface Associated (MUC16) ELISA试剂盒

Human Mucin 16, Cell Surface Associated (MUC16) interaction partners

1. The expression profile of studied Mucins MUC16 and MUC1 (显示 MUC1 ELISA试剂盒) and truncated O-glycans was not associated with the site of origin of ovarian cancer (OVCA) cell lines

2. Serum HE4 (显示 WFDC2 ELISA试剂盒) with its high specificity is useful in ruling out ovarian malignancy especially among the premenopausal women and Risk of Ovarian Malignancy Algorithm (ROMA)which is the combination of both serum CA 125 and HE4 (显示 WFDC2 ELISA试剂盒), appears to be an all-rounder with overall good sensitivity and specificity especially among the postmenopausal women.

3. CA125 appears the most reliable biomarker for OC monitoring, whereas HE4 (显示 WFDC2 ELISA试剂盒) contributes additional information only in a minority of cases

4. The level of HE4 (显示 WFDC2 ELISA试剂盒) in ovarian cancer ascites may reflect the therapeutic effect of ovarian cancer patients, and a high level of HE4 (显示 WFDC2 ELISA试剂盒) might predict chemoresistance and the possibility of ascites formation. The determination of the expression of HE4 (显示 WFDC2 ELISA试剂盒) alone or combined with CA125 levels in both serum and ascites in ovarian cancer patients with ascites may have important significance for guiding and improving the treatment

5. Lower CA125 serum levels, negative vascular invasion, and wild-type BRAF (显示 BRAF ELISA试剂盒) status were significantly associated with improved 2-year DFS (显示 FST ELISA试剂盒) rates among patient with stage III disease who received adjuvant chemotherapy.

6. We can infer from this study that increased maternal serum CA 125 levels are associated with the preeclampsia and its severity.

7. Serum CA125 concentrations are correlated with coronary artery calcification score in the population without known coronary artery disease.

8. Serum Smac (显示 DIABLO ELISA试剂盒) expression level was significantly lower in the EAOC group than in the control group and benign ovarian tumor group (P< 0.05), while HE4 (显示 WFDC2 ELISA试剂盒) and CA125 expression levels were significantly higher in the EAOC group than the other two groups.

9. High serum CA125 level is associated with epithelial ovarian cancer.

10. Serum CA-125 was significantly different between infertile women with and without pelvic endometriosis.

Mouse (Murine) Mucin 16, Cell Surface Associated (MUC16) interaction partners

1. Mesothelin (显示 MSLN ELISA试剂盒)/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.(

2. MAMs MUC1 (显示 MUC1 ELISA试剂盒) and MUC16 contribute to the maintenance of immune homeostasis at the ocular surface by limiting TLR-mediated innate immune responses.

3. MUC16 functions as an oncogene (显示 RAB1A ELISA试剂盒). The cytoplasmic tail is critical for MUC16 oncogenic properties.

4. Data show that intraperitoneal injections of living CA 125 positive cells of OVCAR-3 cell line, and boosted by intravenous injection of the purified extracellular domain of CA 125 was found to have excellent immunoreactivity for CA 125 mAb production.

5. the presence of MUC16 in murine ovarian cancer and in normal tissues

6. Lack of any prominent abnormal phenotype in Muc16 knockout mice suggests that CA125/MUC16 is not required for normal development or reproduction