anti-Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) 抗体

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. 再加上,我们可以发Mitochondrially Encoded NADH Dehydrogenase 1 试剂盒 (11)Mitochondrially Encoded NADH Dehydrogenase 1 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MT-ND1 4535 P03886
MT-ND1 26193  
MT-ND1 17716 P03888
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antibodies-online.cn销售最多的anti-Mitochondrially Encoded NADH Dehydrogenase 1 抗体

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产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 WB Western blot analysis of MT-ND1 expression in HeLa (A) whole cell lysates. 200 μL 13至14个工作日
非结合性 IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MT-ND1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using MT-ND1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2至3个工作日
非结合性 ELISA, IHC, WB Western Blot (WB) analysis of specific cells using ND1 Polyclonal Antibody. 100 μL Available
非结合性 ELISA, ICC, IF, IHC, WB ABIN6275280 staining Hela by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod ABIN6275280 at 1/100 staining Human lung cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL 11至12个工作日
非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti MT-ND1 Polyclonal Antibody, Unconjugated (ABIN702625) at 1:200 followed by conjugation to the secondary antibody and DAB staining Paraformaldehyde-fixed, paraffin embedded rat kidney, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with MT-ND1 Polyclonal Antibody, Unconjugated  at 1:200 overnight at 4°C, followed by a conjugated secondary for 20 minutes and DAB staining. 100 μL 3至7个工作日
小鼠 非结合性 ICC, IHC, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg 13至16个工作日
非结合性 IF, IHC, WB Western blot analysis of extracts of various cell lines, using MT-ND1 antibody (ABIN1873774) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. 100 μL 11至13个工作日
小鼠 非结合性 ELISA, WB ND1 polyclonal antibody (A01), Lot # NIH48060209QCS1 Western Blot analysis of ND1 expression in HepG2 . Western Blot detection against Immunogen (31.72 KDa) . 50 μL 11至12个工作日
非结合性 ICC, IHC, WB Western Blot; Sample: Porcine Liver lysate; Primary Ab: 3µg/ml Rabbit Anti-Human ND1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) Figure. Western Blot; Sample: Recombinant protein. 100 μg 15至18个工作日
非结合性 ELISA, IHC (p), WB 200 μL 12至14个工作日

引用最多的anti-Mitochondrially Encoded NADH Dehydrogenase 1 抗体

  1. Human Polyclonal MT-ND1 Primary Antibody for ELISA, WB - ABIN561868 : Karamanlidis, Nascimben, Couper, Shekar, del Monte, Tian: Defective DNA replication impairs mitochondrial biogenesis in human failing hearts. in Circulation research 2010 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal MT-ND1 Primary Antibody for WB - ABIN5664968 : Li, Zhang, Wang, Zhou, Yin, Fan, Nie, Wang, Fu, Chen, Wang: MicroRNA-21 Lowers Blood Pressure in Spontaneous Hypertensive Rats by Upregulating Mitochondrial Translation. in Circulation 2016 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal MT-ND1 Primary Antibody for WB - ABIN6675142 : Li, Zhou, Li, Li, Long, Chen, Zhang, Li, Feng: WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity. in Free radical biology & medicine 2018 (PubMed)
    Show all 2 Pubmed References

更多抗Mitochondrially Encoded NADH Dehydrogenase 1的相互作用对抗体

Human Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) interaction partners

  1. Our study suggests to include haplogroup T as a possible genetic background influencing LHON penetrance and to consider the increase of mtDNA copy number as a protective factor from vision loss regardless the hetero/homoplasmic status of LHON primary mutations.

  2. the abnormal stable complex of FUS-R521C/PRMT1/Nd1-L mRNA could contribute to neurodegeneration upon oxidative stress.

  3. This review focuses on the role of mitochondrial genes in causing LHON and therapeutics available for treating the disease. A systematic search has been adopted in various databases using the keywords "LHON," "mitochondria," "ND1," "ND4," "ND6," and "therapy" and the following review on mitochondrial genetics.

  4. In this study, 27.5% mutation was detected in North Indian LHON families. These results suggest that m.G11778A mutation is more frequent in this population. The results of the present study are compatible with studies of an Asian population and Northern European population.

  5. The MT-ND1 m.3635G>A mutation has resulted in decreased efficiency of ATP synthesis.

  6. the MT-ND1 gene is a hot spot for mutations associated with LHON.

  7. The present systematic review and meta-analysis suggest that mtDNA T4216C variation is a contributory factor in susceptibility to Multiple Sclerosis

  8. ND1 genetic polymorphisms associated with breast cancer in Mizoram mongloid population.

  9. The m.3472T>C substitution in mtDNA could be associated with risk of Leber's hereditary optic neuropathy. It was also found that this mutation led to dysfunction of respiratory chain complex I and decreased membrane potential, but reactive oxygen species level in the cells was within normal range

  10. The present study revealed no association between MS and T4216C variation in the ND1 mtDNA gene in the Iranian population.

  11. The present analysis reveals a high number (358) of mtDNA alterations and a significant decrease in complex I activity in the FTLD population.

  12. MT-NDA1 new genetic mutation was found in patients with multiple congenital cardiac abnormalities.

  13. respiratory deficiency caused by the m.3635G>A mutation results in decreased efficiency of mitochondrial ATP synthesis; these mitochondrial dysfunctions caused an increase in production of reactive oxygen species in the mutant cybrids; data provide direct evidence for the m.3635G>A mutation leading to Leber's hereditary optic neuropathy

  14. ND1 T3866C mutation is associated with Chinese families with Leber's hereditary optic neuropathy.

  15. To investigate the pathophysiology of Leber's hereditary optic neuropathy (LHON), a cohort of 1164 Han Chinese subjects with LHON were screened for ND1 G3460A mutation.

  16. These results demonstrate that the energetic impairment caused by the almost homoplasmic m.3571insC mutation perturbs cellular metabolism leading to a decreased steady state level of components of very important mitochondrial NAD-dependent dehydrogenases.

  17. m.3460G>A/MT-ND1 mutation caused only a reduction in mitochondrial complex I(CI) activity, whereas the m.3571insC/MT-ND1 and the m.3243A>G/MT-TL1 mutations induced a severe structural and functional CI alteration.

  18. Novel mutations m.3959G>A and m.3995A>G in mitochondrial gene MT-ND1 associated with MELAS.

  19. In Sherpa people, 2 mutations are ND1 mutants. One of them was reported as the primary mutation for Leber's hereditary optic neuropathy suggesting a certain effect on Complex I function and might be important in the altitude adaptation for Sherpa people.

  20. we describe here a heteroplasmic mutation in the MT-ND1 gene that strongly suggest to cause epileptic encephalopathy: West syndrome (WS) patient with unidentified etiology that evolved to Lennox-Gastaut syndrome.

Mitochondrially Encoded NADH Dehydrogenase 1 (MT-ND1) 抗原简介


Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).

Gene names and symbols associated with MT-ND1

  • NADH dehydrogenase, subunit 1 (complex I) (ND1) 抗体
  • NADH dehydrogenase subunit 1 (ND1) 抗体
  • peptidylprolyl isomerase A (PPIA) 抗体
  • NADH dehydrogenasesubunit 1 (nad1) 抗体
  • mitochondrial NADH-ubiquinone oxidoreductase chain 1 (mt:ND1) 抗体
  • cypA 抗体
  • MT-ND1 抗体
  • MTND1 抗体
  • NADH1 抗体
  • ND1 抗体

Protein level used designations for MT-ND1

NADH dehydrogenase subunit 1 , NADH-ubiquinone oxidoreductase chain 1 , PPIase A , cyclophilin A , cyclosporin A-binding protein , peptidyl-prolyl cis-trans isomerase A , rotamase A

4535 Homo sapiens
26193 Rattus norvegicus
17716 Mus musculus
807636 Gallus gallus
804476 Canis lupus familiaris
808501 Sus scrofa
808226 Oryctolagus cuniculus
493966 Felis catus
1734038 Acanthamoeba castellanii
192473 Drosophila melanogaster
808212 Branchiostoma lanceolatum
807667 Ascaris suum
807966 Locusta migratoria
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