anti-Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) 抗体

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. 再加上,我们可以发MMP1 蛋白 (52)MMP1 试剂盒 (47)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MMP1 4312 P03956
MMP1 300339  
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antibodies-online.cn销售最多的anti-MMP1 抗体

Showing 10 out of 291 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 WB 100 μg 4至6个工作日
非结合性 IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  1.25ug/ml  Positive Control:  Jurkat cell lysate Sample Type: Equine Cartilage ExplantsPrimary Dilution: 1:800Secondary Antibody: Bio-Rad 170-5046 Secondary Dilution: 1:100,000Image Submitted By: Adam WilliamsUniversity of Nottingham 100 μL 2至3个工作日
非结合性 IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat Achilles tendon labeled with Anti-MMP-1 Polyclonal Antibody , Unconjugated, followed by conjugation to the secondary antibody and DAB staining Human colon carcinoma lysate probed with Anti MMP1 Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. Predicted band 54kD. Observed band size: 27kD and 54kD 100 μL 3至7个工作日
小鼠 HRP EIA, IHC (fro), IHC (p), WB   1 mL 6至8个工作日
非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using MMP1 antibody. Western blot analysis of extracts of various cell lines, using MMP1 antibody. 100 μL 13至14个工作日
Cow 非结合性 IHC, WB WB Suggested Anti-MMP1 Antibody Titration:  2.5ug/ml  Positive Control:  HT1080 cell lysate MMP1 is supported by BioGPS gene expression data to be expressed in HT1080 Sample Type: Human Macrophange CellsGreen: primaryRed: phallodinBlue: DAPIYellow: green/redPrimary Dilution: 1:200Secondary Antibody: anti-Rabbit IgG-FITCSecondary Dilution: 1:1000Image Submitted By: Milan FialaUniversity of California, Los Angeles 100 μL 2至3个工作日
小鼠 非结合性 IF (p), IHC (p) Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-MMP-1 Polyclonal Antibody, Unconjugated (ABIN668931) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat colitis labeled with Anti-MMP-1 Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL 3至7个工作日
非结合性 IHC (p), WB IHC-P Image MMP1 antibody detects MMP1 protein at secreted on human endometrial carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human endometrial carcinoma. MMP1 antibody , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE antibody diluted at 1:1000 100 μL 3至4个工作日
非结合性 IC, IF, IHC, WB Immunofluorescent analysis of MMP1 staining in MCF7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL 13至14个工作日
小鼠 非结合性 ELISA, FACS, IF, IHC, WB 100 μL 11至14个工作日

引用最多的anti-MMP1 抗体

  1. Human Polyclonal MMP1 Primary Antibody for WB - ABIN3043405 : Man, Gao, Zhang, Liu, Yan, Huang, Liu: Formosanin C-inhibited pulmonary metastasis through repression of matrix metalloproteinases on mouse lung adenocarcinoma. in Cancer biology & therapy 2011 (PubMed)
    Show all 13 Pubmed References

  2. Polyclonal MMP1 Primary Antibody for IHC (p), IP - ABIN541021 : Metzger, Negm, Plentz, Weismüller, Wedemeyer, Karlsen, Dakna, Mullen, Mischak, Manns, Lankisch: Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders. in Gut 2012 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668931 : Luo, Zhang, Wang, Hu, Song, Zhang: The inhibitory effect of salmon calcitonin on intervertebral disc degeneration in an ovariectomized rat model. in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2014 (PubMed)
    Show all 6 Pubmed References

  4. Human Polyclonal MMP1 Primary Antibody for IF (p), IHC (p) - ABIN668466 : Lu, Cao, Liu, Li, Chen, Fu, Zhang, Liu, Luo, Wang, Li, Caterson: The effects of mycotoxins and selenium deficiency on tissue-engineered cartilage. in Cells, tissues, organs 2012 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal MMP1 Primary Antibody for FACS, IF - ABIN966588 : Genevay, Finckh, Mezin, Tessitore, Guerne: Influence of cytokine inhibitors on concentration and activity of MMP-1 and MMP-3 in disc herniation. in Arthritis research & therapy 2010 (PubMed)
    Show all 2 Pubmed References

  6. Human Polyclonal MMP1 Primary Antibody for IHC, WB - ABIN3021680 : Wang, Hu, Zhou, Xiong, Zhang, Shehada, Hu, Song, Chen: Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling. in Scientific reports 2017 (PubMed)
    Show all 2 Pubmed References

  7. Human Monoclonal MMP1 Primary Antibody for ICC, FACS - ABIN969287 : Guan, Shu, Fu, Liu, Xu, Wu: Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells. in FEMS microbiology letters 2009 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal MMP1 Primary Antibody for IHC, WB - ABIN6672624 : Yu, Ding, Zhu, Qu, Zhang, Liu, Chen: IL-22 mediates the oral mucosal wound healing via STAT3 in keratinocytes. in Archives of oral biology 2017 (PubMed)
    Show all 2 Pubmed References

  9. Human Monoclonal MMP1 Primary Antibody for ELISA, FACS - ABIN4334919 : Kim, Park, Kim, Koh, Yoon, Cho, Park: Periostin in Mature Stage Localized Scleroderma. in Annals of dermatology 2017 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal MMP1 Primary Antibody for ICC - ABIN1883181 : Yamakawa, Uchida, Matthay, Makita: Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. in American journal of physiology. Lung cellular and molecular physiology 2011 (PubMed)


Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. Finding show that increase serum levels of MMP-1 in a multivariate regression model were independent predictors of concomitant COPD and carotid plaque.

  2. These results suggested that MMP1 may be pivotal to the transition from normal skin to premalignant lesions to squamous cell carcinoma

  3. The expression of MMP-1 and MMP-9 is up-regulated by smooth muscle cells after their cross-talk with macrophages in high glucose conditions.

  4. This study indicates that a2(I) homotrimers are susceptible to MMP-1, proves that the presence of an a1(I) chain is not a requirement for a2(I) cleavage, and supports the importance of local unfolding of a2(I) in collagenase cleavage.

  5. Study found that recombinant human MMP1 significantly inhibited and disrupted biofilms of vancomycin sensitive and vancomycin resistant Enterococcus faecalis strains. The mechanism of antibiofilm activity is speculated to be linked with bacterial growth inhibition and degradation of biofilm matrix proteins by MMP1.

  6. Data show that matrix metalloproteinase 1 (MMP-1) as a critical downstream target of golgi associated kinase 1B (FAM198B) and implicate FAM198B as a potential tumor suppressor and to be a prognostic marker in lung adenocarcinoma.

  7. Mechano-growth factor regulates cyclic stretch-induced osteogenic differentiation and MMP-1, MMP-2 expression in human periodontal ligament cells by activating MEK/ERK1/2 signaling pathway.

  8. Meta-analysis showed that -1607 1G/2G polymorphism may increase the susceptibility to Osteoarthritis among the younger populations (<60 years).

  9. we compared the expression of MMP1, MMP2, MMP7, and MMP9, well known as secreted MMPs, and found that MMP expression varied in lesions with different histological grade,histological subtype, and type of invasion.

  10. Elevated MMP-1 and reduced TIMP-1 were found in obstructed defecation syndrome associated with internal rectal prolapse

  11. miR-675-5' induces expression of MMP1 and MMP13.

  12. MMP1-PAR1 signaling system drives chronic inflammatory signaling in plaques and the progression of atherosclerosis.

  13. Hepatitis C virus/Hepatitis B Virus co-infected patients with significant fibrosis did not show any significant difference (P > 0.05) from HCV mono-infected patients with respect to HCV-NS4, collagen III and MMP-1.

  14. The present study also revealed MMP-1-positive Hepatic progenitor cell in the early stages of nonalcoholic steatohepatitis.

  15. A TGFb1 inhibitor was also applied, which attenuated the effects of mechanical force on Human gingival fibroblasts (HGF) proliferation, and COL1 and MMP1 expression, thus suggesting that TGFb signaling pathways may mediate the mechanical forceinduced alterations observed in HGFs.

  16. The odonto/osteogenic differentiation ability of stem cells from apical papilla (SCAPs) ascended after repression of hsa-let-7b, which was then reversed after co-transfection with siMMP1. Together, hsa-let-7b can suppress the odonto/osteogenic differentiation capacity of SCAPs by targeting MMP1.

  17. this case-control study confirms that MMP-1 gene rs1799750 polymorphism increases the risk of knee osteoarthritis in Chinese Han population.

  18. Study revealed that MMP1-1607 (1G>2G) polymorphism was significantly associated with elevated risk of cancers. [meta-analysis]

  19. cFos bound to the AP-1 cis element within the proximal MMP1 promoter only when the gene was transcriptionally silent as previously observed for MMP13. cFos contributes to MMP1 expression. Silencing of ATF3 (a prime MMP13 modulator) did not affect MMP1 expression whilst silencing CSRNP1 resulted in substantial repression of MMP1 but not MMP13.

  20. activation of MMP-1 depends on increased plasmin activity

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. the identification of MMP1 and MMP10 genes in swine is reported.

  2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c pathway and may be due to enhanced phosphorylation of mmp1

  3. Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. there are only two MMP genes in Drosophila, DmMmp1 and DmMmp2, which makes Drosophila an attractive system to analyze the basis of MMP specificity. Previously, Drosophila MMPs have been categorized by their pericellular localization, as Mmp1 appeared to be secreted and Mmp2 appeared to be membrane-anchored, suggesting that protein localization was the critical distinction in this small MMP family

  2. results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.

  3. This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.

  4. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

  5. Data indicate that matrix metalloproteinases mmp1 and mmp2 mutants have distinct heart phenotypes.

  6. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

  7. A primary function of Mmp1, under the control of the JNK pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

  8. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut homeostasis

  9. Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development.

  10. MMP activity is essential for embryonic motor axon fasciculation

  11. Study identified three genes, regeneration (rgn), augmenter of liver regeneration (alr) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Silk Worm Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. Moderate inhibition of matrix metalloproteinases (Mmp1, Mmp2, Mmp3) activity via inhibitor treatments delayed fat body cell dissociation and ovary development, while severe inhibition blocked these developmental processes and eventually led to pupal lethality.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA, leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

  2. The expression patterns of MMP1, MMP2, and MMP8 were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2, and MMP8 expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2, and MMP8 were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. Data suggest that luteolytic factors (such as interferon gamma, tumor necrosis factor alpha, and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. The results showed that a decrease in MMP-1 and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

  6. MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB

  7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  8. the differential expression and localization of membrane-type 1 matrix metalloproteinase in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2

  9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (follicular apex vs. base) for the preovulatory collagenolysis required for follicle rupture

  10. identification of MT1-MMP in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

  11. MT1-MMP has a role in signaling events mediating EGFR transactivation

  12. IL-4 and IL-13 affect airway smooth muscle (SM) gel contraction via a phosphatidylinositol 3-kinase mediated endogenous production of MMP-1 that alters the interaction between SM cells and collagen fibers.

  13. In cervix, MMP1 is only active during the final cervical ripening process at parturition.

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. There were clear time-dependent degenerative changes in the histology of the medial meniscus after PCL rupture. The high expression of TIMP-1, MMP-1 and MMP-13 in the cartilage may be responsible for the degeneration, and PCL rupture may trigger meniscus degradation and ultimately osteoarthritis

  2. These results suggest that PEP-1-SIRT2 promotes matrix metalloproteinases-induced dedifferentiation via ERK signaling in articular chondrocytes. .

  3. the total content and active forms of matrix metalloproteinases (MMPs)-1, -3, and -13 was measured to assess the potential role of the mechanical environment in regulation of matrix turnover by ligament fibroblasts.

  4. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. ANXA2 and MMP1 might participate in remodeling during wound healing in the horse.

  2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

  3. These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) interaction partners

  1. matrix metalloproteinases 7, 9, and 18 are required in vivo for macrophage migration during embryonic development

MMP1 抗原简介


Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with MMP1

  • matrix metallopeptidase 1 (MMP1) 抗体
  • Matrix metalloproteinase 1 (Mmp1) 抗体
  • matrix metalloproteinase 1 (RB11133) 抗体
  • matrix metalloproteinase 1 (Mmp1) 抗体
  • matrix metallopeptidase 1 (interstitial collagenase) (MMP1) 抗体
  • matrix metallopeptidase 1 S homeolog (mmp1.S) 抗体
  • interstitial collagenase (LOC100727966) 抗体
  • matrix metallopeptidase 1 (Mmp1) 抗体
  • CG4859 抗体
  • CLG 抗体
  • Clgn 抗体
  • col4 抗体
  • dm1-MMP 抗体
  • Dmel\\CG4859 抗体
  • dmmp1 抗体
  • l(2)k04809 抗体
  • MMP-1 抗体
  • Mmp1 抗体
  • Mmp 1 抗体
  • Mmp1a 抗体
  • mmp18 抗体

Protein level used designations for MMP1

fibroblast collagenase , interstitial collagenase , matrix metalloprotease 1 , matrix metalloproteinase 1 , MMP-1 , matrix metalloproteinase 1 (type I collagenase) , matrix metalloproteinase-1 , CG4859-PC , CG4859-PD , CG4859-PE , CG4859-PF , CG4859-PG , CG4859-PH , CG4859-PI , CG4859-PJ , CG4859-PK , CG4859-PL , Mmp1-PC , Mmp1-PD , Mmp1-PE , Mmp1-PF , Mmp1-PG , Mmp1-PH , Mmp1-PI , Mmp1-PJ , Mmp1-PK , Mmp1-PL , collagenase-1 , MMP-18 , collagenase-4 , matrix metalloproteinase-18 , xCol4 , matrix metallopeptidase 1a , matrix metalloproteinase 1a (interstitial collagenase) , myocardial collagenase

4312 Homo sapiens
397320 Sus scrofa
37949 Drosophila melanogaster
1790862 Rhodopirellula baltica SH 1
100144547 Bombyx mori
281308 Bos taurus
100009110 Oryctolagus cuniculus
489428 Canis lupus familiaris
100033896 Equus caballus
495287 Xenopus laevis
101120355 Ovis aries
100727966 Cavia porcellus
300339 Rattus norvegicus
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