anti-M-Phase phosphoprotein 8 (MPHOSPH8) 抗体

Involved in transcriptional regulation. 再加上,我们可以发M-Phase phosphoprotein 8 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
MPHOSPH8 54737 Q99549
MPHOSPH8 290270 G3V8T1
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Showing 10 out of 25 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 交付 价格 详细
非结合性 ELISA, WB Western blot analysis of MPHOSPH8 using COLO205 whole cell lysates Western blot analysis of extracts from 3t3, using MPHOSPH8 Antibody. The lane on the left was treated with blocking peptide. 100 μL 11至12个工作日
小鼠 非结合性 WB MPP8 antibody (mAb) tested by Western blot. Nuclear extract of HEK293 cells (20 µg per lane) probed with MPP8 antibody (mAb) (2 µg/ml dilution). 100 μg 1至2个工作日
非结合性 ELISA, WB   100 μL 11至13个工作日
小鼠 非结合性 IF, WB Western Blot analysis of MPHOSPH8 expression in transfected 293T cell line by MPHOSPH8 MaxPab polyclonal antibody.Lane 1: MPHOSPH8 transfected lysate(28.40 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to MPHOSPH8 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL 11至12个工作日
非结合性 WB Western blot analysis MPHOSPH8 using COLO205 whole cell lysates. 100 μg 11至18个工作日
非结合性 IP, WB   100 μL 11至14个工作日
非结合性 IP, WB   100 μL 11至14个工作日
非结合性 WB   100 μL 11至16个工作日
小鼠 非结合性 WB   10 μg 1至2个工作日
非结合性 ELISA, WB   50 μL 9至11个工作日

更多抗M-Phase phosphoprotein 8的相互作用对抗体

Human M-Phase phosphoprotein 8 (MPHOSPH8) interaction partners

  1. The study demonstrated that MPP8 was associated with non-small cell lung cancer cell proliferation through regulation of HOXA5.

  2. The haploid screen identified HUSH, an epigenetic heterochromatin repressor complex composed of three subunits, TASOR, MPP8 and Periphilin. (Review)

  3. findings demonstrate MPP8 and SIRT1 reciprocally regulate each other's function at multiple molecular layers through physical interaction; disruption of MPP8-SIRT1 interaction de-represses E cadherin expression and reduces cell motility and invasiveness suggesting this interplay plays critical role in MPP8- and SIRT1-mediated epithelial-mesenchymal transition

  4. this study identified the HUSH (human silencing hub) complex, comprising three poorly characterized proteins, TASOR, MPP8, and periphilin; this complex is absent from Drosophila but is conserved from fish to humans.

  5. Knockdown analysis of MPP8 in HeLa cells resulted in derepression of a set of genes that are normally expressed in spermatogonia, spermatids and mature sperm, thereby indicating a role for this molecule in silencing testis-related genes in somatic cells.

  6. interaction of HN with MPP8 may play a role in oncogenesis because MPP8 increases tumor cell motility and invasion

  7. these results indicate that the chromatin association of MPP8 is regulated by Cdk-dependent phosphorylation.

  8. These findings reveal the molecular mechanism of selective binding of human MPP8 chromodomain to methylated histone H3K9.

  9. We determined the crystal structure of MPP8 chromodomain in complex with H3K9me3 peptide. MPP8 interacts with at least six histone H3 residues from glutamine 5 to serine 10.

  10. MPP8 mediates E-cadherin gene silencing and promotes breast tumour cell motility and invasion.

M-Phase phosphoprotein 8 (MPHOSPH8) 抗原简介


Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites\; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression (By similarity).

Gene names and symbols associated with MPHOSPH8

  • M-phase phosphoprotein 8 (MPHOSPH8) 抗体
  • M-phase phosphoprotein 8 (Mphosph8) 抗体
  • 1500035L22Rik 抗体
  • 4930548G07Rik 抗体
  • Ab2-008 抗体
  • AU040635 抗体
  • HSMPP8 抗体
  • mpp8 抗体
  • RGD1305133 抗体
  • TWA3 抗体

Protein level used designations for MPHOSPH8

M-phase phosphoprotein, mpp , M-phase phosphoprotein, mpp8 , two hybrid-associated protein 3 with RanBPM

54737 Homo sapiens
75339 Mus musculus
290270 Rattus norvegicus
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