anti-Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) 抗体

KCNIP3 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. 再加上,我们可以发Kv Channel Interacting Protein 3, Calsenilin 蛋白 (13)Kv Channel Interacting Protein 3, Calsenilin 试剂盒 (10)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
KCNIP3 30818 Q9Y2W7
KCNIP3 56461 Q9QXT8
KCNIP3 65199 Q9JM47
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antibodies-online.cn销售最多的anti-Kv Channel Interacting Protein 3, Calsenilin 抗体

Showing 10 out of 166 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 IHC, WB WB Suggested Anti-CSEN Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate Human kidney 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB WB Suggested Anti-Kcnip3 Antibody   Titration: 1.0 ug/ml   Positive Control: Mouse Pancreas 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 WB 100 μg Log in to see 2至3个工作日
$245.00
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from K562 cells treated with forskolin 40nM 30' and 293 cells treated with PMA 125ng/ml 30', using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 IF, IHC, ELISA, WB Western blot analysis of extracts from MCF-7/Jurkat/A549 cells, using Calsenilin/KCNIP3 (Ab-63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Calsenilin/KCNIP3 (Ab-63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2至3个工作日
$302.50
详细
非结合性 EIA, IHC (p), WB 0.4 mL Log in to see 6至8个工作日
$390.50
详细
山羊 非结合性 ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26111] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10525 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10525 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
山羊 非结合性 ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26112] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10526 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10526 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
$485.88
详细
非结合性 WB WB Image Western Blot analysis of KCNIP3 expression in transfected 293T cell line by KCNIP3 polyclonal antibody. A: Non-transfected lysate. B: KCNIP3 transfected lysate. 12% SDS PAGE antibody diluted at 1:500 WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1至2个工作日
$358.60
详细
非结合性 IF, IHC (p), WB Western blot analysis of KChIP3 Antibody (N-term M1) (ABIN388402) in mouse heart tissue lysates (35 µg/lane). KChIP3(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10至11个工作日
$335.50
详细

引用最多的anti-Kv Channel Interacting Protein 3, Calsenilin 抗体

  1. Mammalian Monoclonal KCNIP3 Primary Antibody for ISt, IHC - ABIN1304731 : Menegola, Trimmer: Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 16 Pubmed References

  2. Cow (Bovine) Polyclonal KCNIP3 Primary Antibody for IHC, WB - ABIN2777506 : Zaidi, Thomson, Choi, Buxbaum, Wasco: Intracellular calcium modulates the nuclear translocation of calsenilin. in Journal of neurochemistry 2004 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal KCNIP3 Primary Antibody for ELISA, WB - ABIN4287519 : Rivas, Mellström, Torres, Cali, Ferrara, Terracciano, Zannini, Morreale de Escobar, Naranjo: The DREAM protein is associated with thyroid enlargement and nodular development. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

更多抗Kv Channel Interacting Protein 3, Calsenilin的相互作用对抗体

Human Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. targeting SmgGDS (显示 RAP1GDS1 抗体) induces nucleolar stress, resulting in profound loss of DREAM target gene expression required for G1, S and G2 progression, and ultimately resulting in cell cycle arrest.

  2. Disruption of DREAM and RB-E2F (显示 E2F1 抗体) complexes by oncoproteins from DNA tumor viruses leads to upregulation of cell cycle genes and impairs growth-inhibiting pathways, including the p53 (显示 TP53 抗体)-mediated downregulation of cell cycle genes. [review]

  3. This study shows the application of hydrogen-deuterium exchange mass spectrometry and site-directed mutagenesis to investigate the Ca(2 (显示 CA2 抗体)+) binding properties and the subsequent conformational changes of full-length DREAM. EF-hands undergo large conformation changes upon calcium binding even though the EF-1 (显示 EEF1D 抗体) hand is not capable of binding to Ca(2 (显示 CA2 抗体)+).

  4. Our approach yields high confidence ranked target gene maps for TP53 (显示 TP53 抗体), DREAM, MMB-FOXM1 (显示 FOXM1 抗体) and RB-E2F (显示 E2F1 抗体) and enables prediction and distinction of CC regulation. A web-based atlas at www.targetgenereg.org enables assessing the regulation of any human gene of interest.

  5. downregulation of these genes through the p53 (显示 TP53 抗体)-p21 (显示 CDKN1A 抗体)-DREAM-CDE/CHR pathway appears to be a principal mechanism for G2/M cell cycle arrest by p53 (显示 TP53 抗体).

  6. Our results support the hypothesis that KChIPs enhances Kv4.2 (显示 KCND2 抗体) functional expression by a 1 : 1 suppression of the N-terminal FERN domain and by producing additional positive regulatory effects on functional channel expression.

  7. GCM1 (显示 GCM1 抗体)-directed villous trophoblast differentiation is repressed by DREAM

  8. p53 (显示 TP53 抗体) can repress transcription of cell cycle genes through a p21(WAF1/CIP1 (显示 CDKN1A 抗体))-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.

  9. The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin function.

  10. expression of calsenilin leads to a disruption of presenilin 1 (显示 PSEN1 抗体)/gamma-secretase-mediated epsilon-cleavage of N-cadherin (显示 CDH2 抗体), which results in the significant accumulation of N-cadherin (显示 CDH2 抗体) C-terminal fragment 1

Mouse (Murine) Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. Genome-wide analysis of trigeminal neurons in daDREAM transgenic mice identified cathepsin L (显示 CTSL1 抗体) and the monoglyceride lipase (显示 MGLL 抗体) as two new DREAM transcriptional targets related to pain.

  2. association of PS1 (显示 PSEN1 抗体) carboxyl peptide (residues 445-467, HL9 (显示 DDC 抗体)) with DREAM is calcium dependent and stabilized by a cluster of three aromatic residues: F462 and F465 from PS1 (显示 PSEN1 抗体) and F252 from DREAM.

  3. The association of calcium-bound calmodulin (CaM) with DREAM is mediated by a short amphipathic amino acid sequence located between residues 29 and 44 on DREAM.

  4. The protein DREAM decreases development of L-DOPA-induced dyskinesia in mice and reduces L-DOPA-induced expression of FosB (显示 FOSB 抗体), phosphoacetylated histone H3 (显示 HIST3H3 抗体), and dynorphin-B in the striatum

  5. NS5806 directly interacts with KChIP3 and modulates the interactions between this calcium-binding protein (显示 GUCA1B 抗体) and the T1 domain of the Kv4.3 (显示 KCND3 抗体) channels through reorientation of helix 10 on KChIP3

  6. studies define the critical opposing functions of DREAM and USF1 (显示 USF1 抗体) in inhibiting and inducing A20 (显示 TNFAIP3 抗体) expression

  7. GCM1 (显示 GCM1 抗体)-directed villous trophoblast differentiation is repressed by DREAM

  8. Expression of DREAM in neuroblastoma (显示 ARHGEF16 抗体) cells enhances cisplatin mediated caspase-3 (显示 CASP3 抗体) activity.

  9. Restoring CANT1 (显示 CANT1 抗体) levels in neuroblastoma (显示 ARHGEF16 抗体) clones recovered the phenotype, thus confirming a key role of CANT1 (显示 CANT1 抗体), and of the regulation of its gene by DREAM, in the control of protein synthesis and degradation

  10. In cardiomyocytes, [Ca2 (显示 CA2 抗体)+]i-activated calmodulin kinase II (CaMKII (显示 CAMK2 抗体)) activates downstreamregulatory element (DRE (显示 SUFUH 抗体)) binding transcription factor DREAM, which consequently suppresses the expression of L-type calcium channel 1C-subunit gene (Cacna1c (显示 CACNA1C 抗体)).

Zebrafish Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) interaction partners

  1. zebrafish calsenilin is involved in endocrine cell differentiation and morphogenesis within the pancreas

Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) 抗原简介

蛋白简介

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene names and symbols associated with KCNIP3

  • potassium voltage-gated channel interacting protein 3 (KCNIP3) 抗体
  • Kv channel-interacting protein 4 (LOC5568664) 抗体
  • calsenilin (CpipJ_CPIJ002549) 抗体
  • calsenilin (Tsp_05009) 抗体
  • Kv channel interacting protein 3, calsenilin (Kcnip3) 抗体
  • potassium voltage-gated channel interacting protein 3 (Kcnip3) 抗体
  • Kv channel interacting protein 3b, calsenilin (kcnip3b) 抗体
  • Kv channel interacting protein 3, calsenilin (KCNIP3) 抗体
  • potassium voltage-gated channel interacting protein 3 (kcnip3) 抗体
  • 4933407H12Rik 抗体
  • AI413860 抗体
  • csen 抗体
  • Dream 抗体
  • im:7145308 抗体
  • KChIP3 抗体
  • KCNIP3 抗体
  • R74849 抗体
  • rKChIP3 抗体
  • zgc:73306 抗体

Protein level used designations for KCNIP3

A-type potassium channel modulatory protein 3 , DRE-antagonist modulator , calsenilin , calsenilin, presenilin-binding protein, EF hand transcription factor , kv channel-interacting protein 3 , potassium channel interacting protein 3 , calsenilin, presenilin binding protein, EF hand transcription factor , A-type potassium channel modulating protein 3 , KChIP3 , calsenilin presenilin-binding protein EF hand transcription factor , calsenilin, presenilin-binding protein, EF hand transcription fa , downstream regulatory element-antagonist modulator , Kv channel interacting protein 3, calsenilin

GENE ID SPECIES
30818 Homo sapiens
5568664 Aedes aegypti
6033823 Culex quinquefasciatus
10912880 Trichinella spiralis
56461 Mus musculus
65199 Rattus norvegicus
393755 Danio rerio
459401 Pan troglodytes
513316 Bos taurus
704307 Macaca mulatta
100135241 Xenopus (Silurana) tropicalis
100856050 Canis lupus familiaris
100717101 Cavia porcellus
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