anti-Interleukin 27 (IL27) 抗体

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. 再加上,我们可以发IL27 试剂盒 (53)IL27 蛋白 (23)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
IL27 53342 Q8TAD2
IL27 365368  
IL27 246779 Q8K3I6
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antibodies-online.cn销售最多的anti-IL27 抗体

Showing 10 out of 164 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 WB WB Suggested Anti-IL27 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Fetal Lung 100 μL Log in to see 2至3个工作日
小鼠 大鼠 非结合性 WB 25 μL Log in to see 1至2个工作日
小鼠 非结合性 CyTOF, FACS Detection of IL-27 in PHA + IL-2-treated Human PBMC by Flow Cytometry. Human PBMC, treated with 5 ug/mL PHA and 5 ng/mL rhIL-2 (dark orange filled histogram), or untreated (open histogram, yellow line) were stained with Mouse Anti-Human IL-27 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 8至9个工作日
非结合性 WB 100 μg Log in to see 7至9个工作日
非结合性 IHC (p), WB 50 μg Log in to see 7至9个工作日
小鼠 非结合性 WB IL27 Antibody (Center) (ABIN658144) western blot analysis in mouse liver tissue lysates (35 µg/lane). This demonstrates the IL27 antibody detected the IL27 protein (arrow). 400 μL Log in to see 10至11个工作日
小鼠 Biotin WB   100 μg Log in to see 1至2个工作日
非结合性 ICC, IHC (p), WB Human Lung (formalin-fixed, paraffin-embedded) stained with IL27 antibody ABIN337287 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
非结合性 IHC (p), ELISA, WB Human Spleen, Neutrophils (formalin-fixed, paraffin-embedded) stained with IL27 antibody ABIN351442 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
小鼠 非结合性 ELISA, WB 100 μg Log in to see 7至9个工作日

通过反应活性、应用领域、克隆类型和共轭标记 IL27 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-IL27 抗体

  1. Mouse (Murine) Monoclonal IL27 Primary Antibody for ICS, Neut - ABIN2689756 : Hall, Silver, Hunter: The immunobiology of IL-27. in Advances in immunology 2012 (PubMed)
    Show all 7 Pubmed References

  2. Mouse (Murine) Polyclonal IL27 Primary Antibody for WB - ABIN1043831 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002 (PubMed)

  3. Mouse (Murine) Monoclonal IL27 Primary Antibody for WB - ABIN1043835 : Murugaiyan, Mittal, Weiner: Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)

  4. Human Monoclonal IL27 Primary Antibody for CyTOF, FACS - ABIN4900122 : Seyerl, Kirchberger, Majdic, Seipelt, Jindra, Schrauf, Stöckl: Human rhinoviruses induce IL-35-producing Treg via induction of B7-H1 (CD274) and sialoadhesin (CD169) on DC. in European journal of immunology 2010 (PubMed)


Human Interleukin 27 (IL27) interaction partners

  1. serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barre syndrome

  2. Expression of IL-27 in the serum was markedly increased in patients with sepsis-induced myo (显示 IRF6 抗体)cardial dysfunction compared with that in controls.

  3. IL-27 significantly inhibited the M2 macrophages polarization and dampened the proliferation, migration and metastasis of pancreatic cancer cells and as well enhanced the efficacy of gemcitabine.

  4. IL-27 increased NLRP3 (显示 NLRP3 抗体) inflammasome activation in monocytes with enhanced release of IL-1 beta (显示 IL1B 抗体).

  5. this study shows that interleukin 27 is up-regulated in patients with active inflammatory bowel disease

  6. IL-27 polymorphisms might play a protective role for the development of ulcerative colitis in the Mexican population

  7. IL-27 stimulation activated STAT1 (显示 STAT1 抗体) and STAT3 (显示 STAT3 抗体) in HeLa and T98G cells, suggesting that IL-27 engages the STAT1 (显示 STAT1 抗体)/3 pathway, which then leads to the upregulation of IL-6 (显示 IL6 抗体), IP-10 (显示 CXCL10 抗体), and MIG (显示 CXCL9 抗体)

  8. IL-27 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. stercoralis infections, which suggest the importance of IL-27 and IL-37 in immune modulation in a chronic helminth infection.

  9. IL-27 is a pivotal regulator in endometriotic immune tolerance by triggering Th17 cells to produce IL-10 (显示 IL10 抗体).

  10. HIV and Tat (显示 TAT 抗体) inhibit LPS (显示 IRF6 抗体)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (显示 TAT 抗体) through the inhibition of cIAP-1 (显示 BIRC2 抗体)-TRAF-6 (显示 TRAF6 抗体) and subsequent inhibition of PI3K (显示 PIK3CA 抗体) and p38 (显示 CRK 抗体) MAPKs, whereas HIV through the inhibition of p38 MAPK (显示 MAPK14 抗体) activation.

Mouse (Murine) Interleukin 27 (IL27) interaction partners

  1. these data infer that endopeptidase mediated gliadin degradation by macrophages and concomitant IL-27 production drive differentiation of splenic gliadin-specific Tr1 (显示 TXNRD1 抗体)-like cells in celiac disease

  2. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (显示 TP53 抗体) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  3. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (显示 LTF 抗体).

  4. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS (显示 TLR4 抗体) injection compared with control specimens.

  5. these findings highlight critical roles for IFN-gamma (显示 IFNG 抗体) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

  6. IL-27-induced Sca-1 (显示 Ly6a 抗体)(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (显示 EOMES 抗体) and Blimp1 (显示 PRDM1 抗体).

  7. found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (显示 IL6 抗体) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27

  8. We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.

  9. These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.

  10. results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.

Pig (Porcine) Interleukin 27 (IL27) interaction partners

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 抗原简介


The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Gene names and symbols associated with anti-Interleukin 27 (IL27) 抗体

  • interleukin 17D (IL17D) 抗体
  • interleukin 27 (IL27) 抗体
  • interleukin 27 (Il27) 抗体
  • IL-17D 抗体
  • IL-22 抗体
  • IL-27 抗体
  • IL-27A 抗体
  • IL-27p28 抗体
  • IL27 抗体
  • IL27A 抗体
  • IL27p28 抗体
  • Il30 抗体
  • p28 抗体
  • RGD1561420 抗体

Protein level used designations for anti-Interleukin 27 (IL27) 抗体

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interluekin 27 , interleukin 27 p28 subunit , p28

53342 Homo sapiens
246778 Homo sapiens
365368 Rattus norvegicus
607880 Canis lupus familiaris
614927 Bos taurus
737725 Pan troglodytes
246779 Mus musculus
493187 Sus scrofa
100724612 Cavia porcellus
101122495 Ovis aries
101093822 Felis catus
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