IMPA1 抗体
(Inositol(myo)-1(or 4)-Monophosphatase 1 (IMPA1))
This gene encodes an enyzme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. [provided by RefSeq, Nov 2009].
recommended
recommended
recommended
IMPA1 抗体 by 适用
Find IMPA1 抗体 for a variety of species such as anti-Human IMPA1, anti-Mouse IMPA1, anti-Rat IMPA1. The species listed below are among those available. Click on a link to go to the corresponding products.
IMPA1 抗体 by 应用范围
Find IMPA1 抗体 validated for a specific application such as WB, IF, IHC, ELISA. Some of the available applications are listed below. Click on a link to go to the corresponding products.
IMPA1 抗体 by 抗体来源
Find IMPA1 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.
IMPA1 抗体 by 抗原表位
Find IMPA1 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.
IMPA1 抗体 by 克隆形成能力
Find available monoclonal or polyclonal IMPA1 抗体. Click on a link to go to the corresponding products.
IMPA1 抗体 by 克隆
Find IMPA1 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.
IMPA1 抗体 by 标记
Find IMPA1 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.
Popular IMPA1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (11)
Cat. No.
ABIN6142429
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (3)
Cat. No.
ABIN7246232
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN561484
Quantity
50 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF, IC
Validations
- (3)
Cat. No.
ABIN7306576
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN517151
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Guinea Pig, Human, Monkey, Mouse, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN6744302
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
Cat. No.
ABIN7091252
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA, IF
Validations
Cat. No.
ABIN7115270
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IP
Validations
Cat. No.
ABIN7450359
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
IP
Validations
Cat. No.
ABIN7451266
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB
Validations
Cat. No.
ABIN2610037
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, ICC
Validations
Cat. No.
ABIN7466465
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
Cat. No.
ABIN7467238
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB
Validations
- (1)
Cat. No.
ABIN2787799
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
EIA, RIA
Validations
Cat. No.
ABIN5567428
Quantity
150 μg
Datasheet
Datasheet
Latest Publications for our IMPA1 抗体
: "An NGF-responsive element targets myo-inositol monophosphatase-1 mRNA to sympathetic neuron axons." in: Nature neuroscience, Vol. 13, Issue 3, pp. 291-301, (2010) (PubMed).: "A long hangover from party drugs: residual proteomic changes in the hippocampus of rats 8 weeks after ?-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination." in: Neurochemistry international, Vol. 56, Issue 8, pp. 871-7, (2010) (PubMed).
Aliases for IMPA1 抗体
inositol monophosphatase 1 (impa1) 抗体inositol(myo)-1(or 4)-monophosphatase 1 (impa1) 抗体
inositol (myo)-1(or 4)-monophosphatase 1 (Impa1) 抗体
inositol monophosphatase 1 (Impa1) 抗体
inositol monophosphatase (impa1) 抗体
inositol monophosphatase 1 (IMPA1) 抗体
inositol(myo)-1(or 4)-monophosphatase 1 S homeolog (impa1.S) 抗体
inositol(myo)-1(or 4)-monophosphatase 1 (IMPA1) 抗体
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