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HOXD12 belongs to the homeobox family of genes. 再加上，我们可以发HOXD12 蛋白 (6) 和 HOXD12 试剂盒 (3)和数多这个蛋白质的别的产品。
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Cow (Bovine) Polyclonal HOXD12 Primary Antibody for IHC, WB - ABIN2779774
Goodman: Limb malformations and the human HOX genes. in American journal of medical genetics 2002
Show all 2 Pubmed References
Human Polyclonal HOXD12 Primary Antibody for ELISA, WB - ABIN4319733
Woo, Kharchenko, Daheron, Park, Kingston: A region of the human HOXD cluster that confers polycomb-group responsiveness. in Cell 2010
data show no significant difference in HOXD11, HOXD12 & HOXD13 genotype frequencies between the autism spectrum disorder & healthy controls, but one SNP in promoter region of HOXD11 was observed in only 4 patients with ASD
In human embryonic stem cell (hESCs)differentiation, a 1.8kb region between HOXD11 and HOXD12 (D11.12) that is associated with PcG proteins was discovered, it shows alteration in nuclease sensitivity as hESCs differentiate.
Data show that HOXD12 are important susceptible genes of idiopathic congenital talipes equinovarus.
genes compete for a remote enhancer that recognizes the locus in a polar fashion, with a preference for 5' extremity; modifications in either number or topography of Hoxd loci induced regulatory reallocations affecting both number and morphology of digits
early posterior restriction of Hox gene products sets up an anterior-posterior prepattern, which determines the localized activation of Shh; this signal is then translated into digit morphological asymmetry by promoting the late expression of Hoxd genes
point mutation rather than the entire deletion of Hoxd12, such as in knockout and transgenic mice, causes the abnormal limb phenotype in microdactyly mice
mutant analysis shows that Hoxd11, Hoxd12, and Hoxd13 genetically interact to form and sculpt the forelimb, a potential genetic milieu that may have been exploited by evolutionary adaptation
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
Hox-4.7, mouse, homolog of
, homeo box D12
, homeobox protein Hox-4H
, homeobox protein Hox-D12
, homeobox protein Hox-4.7
, homeobox protein Hox-5.6
, Ghox 4.7
, homeobox protein Hox-4F
, homeobox D12
, homeobox gene D-12
, homeobox protein Hox-D12a
, Homeobox protein Hox-D12a
, homeobox protein HoxD12a