Glutathione S-Transferase mu 4 蛋白 (GSTM4)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. 再加上,我们可以发GSTM4 抗体 (49)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GSTM4 2948 Q03013
GSTM4 499689  
小鼠 GSTM4 GSTM4 14865  
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Showing 8 out of 13 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
大肠杆菌(E. Coli) His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30至35个工作日
HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
小麦胚 GST tag 10 μg Log in to see 11至12个工作日
大肠杆菌(E. Coli) His tag,T7 tag 100 μg Log in to see 15至18个工作日
大肠杆菌(E. Coli) 大鼠 非结合性 SDS-PAGE analysis of Rat GSTm4 Protein. 100 μg Log in to see 11至18个工作日
大肠杆菌(E. Coli) His tag 100 μg Log in to see 15至19个工作日
大肠杆菌(E. Coli) His tag   1 mg Log in to see 2至3个工作日
非结合性   1 mg Log in to see 6 Days

GSTM4 蛋白 by Origin and Source

Origin 在表达 标记
Human , ,
, , ,
Rat (Rattus)

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Human Glutathione S-Transferase mu 4 (GSTM4) interaction partners

  1. Our data suggest that the combined treatment with chemotherapy and GST(GSTM1, GSTM4 and GSTT1 ) inhibitors such as EA might be an interesting option for patients with chemoresistant Hodgkin's lymphoma

  2. There were no significant associations between glutathione-S-transferases and p53 expressions and tumor stage, tumor grade and smoking status (p>0.05).

  3. We observed suggestive associations between survival and GSTT1 copy number and GSTA5, GSTM4, and ABCC4 single nucleotide polymorphisms

  4. A T2517C polymorphism in the GSTM4 gene is associated with risk of developing lung cancer.

  5. a novel splice variant of GSTM4 that resulted from tandem skipping of exons 4 and 5 is identified.

  6. GSTM4 (glutathione S-transferase mu 4) haplotype 1101000 may be an important determinant for lung function growth

  7. GSTM4 contributes to the cancerous behavior of Ewing's sarcoma.



Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Gene names and symbols associated with GSTM4

  • glutathione S-transferase mu 4 (GSTM4)
  • glutathione S-transferase mu 4 (Gstm4)
  • glutathione S-transferase, mu 4 (Gstm4)
  • 1110004G14Rik 蛋白
  • Gstb-4 蛋白
  • Gstb4 蛋白
  • GSTM4-4 蛋白
  • GSTM7-7 蛋白
  • GTM4 蛋白

Protein level used designations for GSTM4

glutathione S-transferase M4 , GST class-mu 4 , GST-Mu2 , GTS-Mu2 , S-(hydroxyalkyl)glutathione lyase M4 , glutathione S-alkyltransferase M4 , glutathione S-aralkyltransferase M4 , glutathione S-aryltransferase M4 , glutathione S-transferase Mu 4 , glutathione S-transferase mu 3 , glutathione S-transferase mu 4 , glutathione-S-transferase, mu 4

457094 Pan troglodytes
699923 Macaca mulatta
2948 Homo sapiens
499689 Rattus norvegicus
14865 Mus musculus
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