anti-Glutathione S-Transferase mu 3 (Brain) (GSTM3) 抗体

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. 再加上,我们可以发Glutathione S-Transferase mu 3 (Brain) 蛋白 (8)Glutathione S-Transferase mu 3 (Brain) 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GSTM3 2947 P21266
GSTM3 14864 P19639
GSTM3 108348148 Q9Z1B2;
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产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-GSTM3 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB <b>WB Suggested Anti-GSTM3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Stomach 100 μL Log in to see 2至3个工作日
山羊 非结合性 ELISA, IF   100 μg Log in to see 6至7个工作日
非结合性 ELISA, IHC, WB Western blot analysis of GSTM3 using anti-GSTM3 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat testis tissue lysate, Lane 2: rat brain tissue lysate, Lane 3: mouse testis tissue lysate, Lane 4: mouse brain tissue lysate, Lane 5: human Hela cell lysate, Lane 6: human MCF-7 cell lysate.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-GSTM3 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for GSTM3 at approximately 26KD. The expected band size for GSTM3 is at 26KD. IHC analysis of GSTM3 using anti-GSTM3 antibody . GSTM3 was detected in paraffin-embedded section of human rectal cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-GSTM3 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Log in to see 4至6个工作日
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 IHC, IHC (p), WB Immunohistochemistry-Paraffin: GSTM3 Antibody [NBP1-83323] - Staining of human testis shows strong cytoplasmic positivity in cells of seminiferus ducts and Leydig cells. Western Blot: GSTM3 Antibody [NBP1-83323] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 0.1 mL Log in to see 10至13个工作日
Cow 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 IHC, WB Western blot analysis of extracts of mouse testis tissue, using GSTM3 antibody. ABIN6273252 at 1/100 staining Human pancreas cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary. 100 μL Log in to see 11至12个工作日
小鼠 GST tag ELISA, IHC, IP, WB SDS-PAGE of Mouse anti-GSTM3 Monoclonal Antibody. Lane 1: Non-reduced Mouse anti-GSTM3 Monoclonal Antibody. Lane 2: 3 µL OPAL Pre-stained Marker . Lane 3: Reduced Mouse anti-GSTM3 Monoclonal Antibody. Load: 1 µg per lane. Predicted/Observed size: Non-reduced at 160 kDa/observed at 180-200 kDa; Reduced at 55, 25 kDa. Non-reduced migrates at slightly higher molecular weight. 100 μg Log in to see 7至9个工作日
非结合性 ICC, IHC, WB Western Blot; Sample: Mouse Cerebellum lysate; Primary Ab: 2µg/mL Rabbit Anti-Human GSTm3 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Log in to see 13至16个工作日

引用最多的anti-Glutathione S-Transferase mu 3 (Brain) 抗体

  1. Human Polyclonal GSTM3 Primary Antibody for ELISA - ABIN314300 : Hong, Heun, Jessen, Popp, Hentschel, Kelemen, Schulz, Maier, Kölsch: Gene variations in GSTM3 are a risk factor for Alzheimer's disease. in Neurobiology of aging 2009 (PubMed)

更多抗Glutathione S-Transferase mu 3 (Brain)的相互作用对抗体

Human Glutathione S-Transferase mu 3 (Brain) (GSTM3) interaction partners

  1. Differential activity of antioxidant enzymes caused by the polymorphism in GSTM3 may contribute to resistance to hormonal therapy through oxidative stress. The GSTM3 rs7483 polymorphism may be a promising biomarker for prostate cancer patients treated with androgen-deprivation therapy (ADT)

  2. The individuals carrying the deletions of GSTM1 (显示 GSTM1 抗体) and GSTT1 (显示 GSTT1 抗体) were at risk for Neurocysticercosis (NCC (显示 SLC12A3 抗体)). Genetic variants of GSTM3 and GSTP1 (显示 GSTP1 抗体) were not associated with NCC (显示 SLC12A3 抗体).

  3. Expression of GSTM3 might be regulated by epigenetic changes in lens tissue. Hypermethylation in GSTM3 promoter and altered histone modification might have a role in the ARC (显示 NOL3 抗体) formation.

  4. This meta-analysis suggested that the GSTT1 (显示 GSTT1 抗体) and GSTM3 polymorphisms might influence osteosarcoma risk.

  5. No associations between the GSTT1, GSTP1, and GSTM3 genotypes and neoplasia risk were observed. In conclusion, we determined the genotype distribution of GST polymorphisms in control subjects and breast cancer patients from northeastern Mexico.

  6. NSD1 (显示 NSD1 抗体) interacted with RNAPII (显示 Pol II 抗体) and bound to GSTM3 -63A/C TATA box.

  7. To identify the genotypes of CYP1A1 (显示 CYP1A1 抗体), GSTM1 (显示 GSTM1 抗体), GSTM3, GSTT1 (显示 GSTT1 抗体) and GSTP1 (显示 GSTP1 抗体) in a case-control study.

  8. All three markers correlated significantly with regional lymph node metastasis: FXYD3 (显示 FXYD3 抗体) (p = 0.0110), S100A11 (显示 S100A11 抗体) (p = 0.0071), and GSTM3 (p = 0.0173) in colon cancer lymphatic metastasis.

  9. This meta-analysis suggests that the GSTM3 A/B polymorphism may be an important protective factor for head and neck cancer, especially of laryngeal cancer and Caucasian populations.

  10. rs1332018 genetic variants in the GSTM3 promoter predispose the host to downregulating GSTM3 expression in kidney, facilitate carcinogenesis, and predict an unfavourable postoperative prognosis of renal cell carcinoma (显示 MOK 抗体).

Mouse (Murine) Glutathione S-Transferase mu 3 (Brain) (GSTM3) interaction partners

  1. Six proteins were regulated at both basal and inducible levels exhibiting the largest dynamic range of Nrf2 (显示 NFE2L2 抗体) regulation: cytochrome CYP2A5, GSTM3, GSTM1 (显示 GSTM1 抗体), ENTPD5 (显示 ENTPD5 抗体),UDPGDH (显示 UGDH 抗体), and EPHX1 (显示 EPHX1 抗体).

  2. Data show that beta-catenin (显示 CTNNB1 抗体) accumulation increases GST activity in nuclei of HCC (显示 FAM126A 抗体) cells, and suggest that GSTM3 may be a novel target gene of the beta-catenin (显示 CTNNB1 抗体)/Tcf (显示 HNF4A 抗体)-Lef complex.

Glutathione S-Transferase mu 3 (Brain) (GSTM3) 抗原简介


Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with GSTM3

  • glutathione S-transferase mu 3 (GSTM3) 抗体
  • glutathione S-transferase Mu 3 (GSTM3) 抗体
  • glutathione S-transferase, mu 3 (Gstm3) 抗体
  • glutathione S-transferase Mu 3 (LOC479911) 抗体
  • glutathione S-transferase mu 3 (Gstm3) 抗体
  • Fsc2 抗体
  • GST5 抗体
  • GSTB 抗体
  • GSTM3-3 抗体
  • GTM3 抗体
  • mGSTM5 抗体

Protein level used designations for GSTM3

GST class-mu 3 , S-(hydroxyalkyl)glutathione lyase M3 , brain GST , brain type mu-glutathione S-transferase , glutathione S-alkyltransferase M3 , glutathione S-aralkyltransferase M3 , glutathione S-aryltransferase M3 , glutathione S-transferase M3 (brain) , glutathione S-transferase Mu 3 , glutathione S-transferase, Mu-3 , hGSTM3-3 , glutathione S-transferase M3 , glutathione S-transferase GT9.3 , glutathione S-transferase mu 3 , glutathione-S-transferase, mu , glutathione S-transferase Mu 3-like , glutathione S-transferase Mu 5 , GST class-mu 5

2947 Homo sapiens
100169963 Felis catus
14864 Mus musculus
615507 Bos taurus
457128 Pan troglodytes
479911 Canis lupus familiaris
700303 Macaca mulatta
100061826 Equus caballus
100514231 Sus scrofa
100356052 Oryctolagus cuniculus
100732625 Cavia porcellus
102188913 Capra hircus
108348148 Rattus norvegicus
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