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GBGT1 encodes a member of the histo-blood group ABO gene family that encodes glycosyltransferases with related but distinct substrate specificity.
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GBGT1 expression is epigenetically silenced through promoter hypermethylation in ovarian cancer.
The Fs synthase gene, GBGT1, in A(pae) individuals encoded an arginine to glutamine (显示 GFPT1 抗体) change at residue 296.
This gene encodes a member of the histo-blood group ABO gene family that encodes glycosyltransferases with related but distinct substrate specificity. This protein plays a role in synthesizing Forssman glycolipid (FG), a member of the globoseries glycolipid family. Human cells do not normally produce FG but produce the precursor glycolipids globotriaosylceramide and globoside. This protein may be involved in the tropism and binding of pathogenic organisms.
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
, Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
, Forssman glycolipid synthetase (FS)
, Forssman synthetase
, forssman glycolipid synthase-like protein
, forssman glycolipid synthase
, forssman glycolipid synthetase
, forssman glycolipid synthetase-like protein
, UDP-GalNAc:globoside alpha-1,3-N-acetylgalactosaminyltransferase
, forssman synthetase