Gasdermin A 蛋白 (GSDMA)

Induces apoptosis.. 再加上,我们可以发Gasdermin A 抗体 (31)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
GSDMA 57911 Q9EST1
大鼠 GSDMA GSDMA 360619  
GSDMA 284110 Q96QA5
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产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
HEK-293 Cells Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 11 Days
大肠杆菌(E. Coli) 非结合性   100 μg Log in to see 11至18个工作日

GSDMA 蛋白 by Origin and Source

Origin 在表达 标记
Mouse (Murine)

Human , ,

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Human Gasdermin A (GSDMA) interaction partners

  1. GSDMA is upregulated in systemic sclerosis monocyte-derived macrophages but not in the skin; and is an expression quantitative trait locus in systemic sclerosis macrophages and lipopolysaccharide/interferon gamma (IFNgamma)-stimulated monocytes. A systemic sclerosis macrophage transcriptome signature is characterized by upregulation of glycolysis, hypoxia and mTOR signaling and a downregulation of IFNgamma response pat...

  2. modest changes (8-13%) in promoter methylation levels of ZPBP2 and GSDMA may cause substantial changes in RNA levels and allelic expression of ZPBP2 and ORMDL3 is mediated by DNA methylation

  3. GSDMA was identified as a susceptibility gene for systemic sclerosis.

  4. we investigated the association between GSDMA and GSDMB variants and the incidence of adult and childhood asthma among Jordanians.An association between the GSDMB T/C single nucleotide polymorphism (SNP) genotype and the incidence of childhood asthma was found

  5. The local genotype influences methylation levels at SLC22A5 and ZPBP2 promoters independently of the asthma status. Further studies are necessary to confirm the relationship between GSDMA-ZPBP2 and SLC22A5 methylation and asthma in females and males separately.

  6. Based on our results and published findings on GSDMA, GSDMB, LRRC3C, and related proteins, we propose that this locus in part affects IBD susceptibility via effects on apoptosis and cell proliferation

  7. Study identified significantly white blood cell count (WBC) level associated SNPs of three separate genes GSDMA, MED24, and PSMD3 in European continent (EA) subjects.

  8. The GSDMA (rs7212938) and GSDMB (rs7216389) polymorphisms are associated with asthma susceptibility and intermediate asthma phenotypes.

  9. Results suggest an association of 17q21 polymorphisms with ORMDL3, GSDMA expression, and IL-17 secretion early in life. These observations may imply a functional role of the 17q21 locus affecting T-cell development during immune maturation.

  10. The present data suggest that TGF-beta, LMO1, possibly RUNX3, and GSDM form a regulatory pathway for directing the pit cells to apoptosis.

  11. Study investigated the expression pattern of the GSDM family genes in the upper gastrointestinal epithelium and cancers.

  12. Evolutionary recombination hotspot around the GSDML-GSDM locus is closely linked to oncogenomic recombination hotspot around the PPP1R1B-STARD3-TCAP-PNMT-PERLD1-ERBB2-C17orf37-GRB7 amplicon at human chromosome 17q12.

蛋白简介Gasdermin A (GSDMA)


Induces apoptosis.

Gene names and symbols associated with Gasdermin A 蛋白 (GSDMA)

  • gasdermin A (Gsdma)
  • gasdermin A (GSDMA)
  • BB149167 蛋白
  • GSDM 蛋白
  • GSDM1 蛋白
  • Gsdma1 蛋白
  • H312E 蛋白

Protein level used designations for Gasdermin A 蛋白 (GSDMA)

gasdermin 1 , gasdermin A1 , gasdermin-1 , gasdermin-A , gasdermin-A1 , gasdermin A

57911 Mus musculus
360619 Rattus norvegicus
426132 Gallus gallus
608276 Canis lupus familiaris
618583 Bos taurus
698841 Macaca mulatta
746070 Pan troglodytes
100054598 Equus caballus
284110 Homo sapiens
100728788 Cavia porcellus
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