Use your antibodies-online credentials, if available.
GJB4 encodes a transmembrane connexin protein that is a component of gap junctions. 再加上，我们可以发Gap Junction Protein, beta 4, 30.3kDa 蛋白 (4)和数多这个蛋白质的别的产品。
Showing 10 out of 47 products:
Human Polyclonal GJB4 Primary Antibody for WB - ABIN1882071
Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003
Show all 4 Pubmed References
These indicate possible involvement of Cx30.3 in the rapid formation and/or decomposition of gap junctions; implying a functional relay between Cx30.3 and other systems such as adhesion proteins.
Cx30 regulates cell adhesion and migration; its modulation of glutamate transport occurs independently of its channel function and is mediated by morphological changes controlling insertion of astroglial processes into synaptic clefts.
Connexin30.3-deficient mice exhibit reduced behavioural responses to a vanilla scent.
Appears to be constitutively expressed in certain renal tubular segments and cells.
GJB4 may be a genetic risk factor for the development of nonsyndromic hearing loss and the data from the present study can be used to direct the clinical evaluation and effectively manage the care of families of children with GJB4.
In this study, we found no mutations of GJB4 in two Progressive symmetrical erythrokeratoderma families.
Letter: describe erythrokeratodermia variabilis phenotype related to novel mutation in GJB4 gene.
Mutation analysis of GJB3 and GJB4 in Chinese patients with erythrokeratodermia variabilis.
Bidirectional sequencing of the coding region of GJB4 revealed a novel c.295G>A missense mutation.
There were no mutations found in the GJB4 gene and the true pathogenesis of progressive symmetrical erythrokeratodermia remains unknown.
A common frameshift mutation and other variants in GJB4 (connexin 30.3): Analysis of hearing impairment families
the involvement of connexin gene 30.3 (GJB4) in the etiology of erythrokeratodermia variabilis
These results not only provide new insights into epidermal connexin synthesis and polymerization, but also allow a novel molecular explanation for the similarity of EKV phenotypes.
Not all clinically diagnosed individuals with erythrokeratoderma variabilis harbor Cx30.3 disease-associated mutations.
Five patients with erythrokeratodermia variabilis of Mendes da Costa and progressive symmetric erythrokeratodermia of Gottron had the same mutation in the GJB4 gene causing the amino acid substitution p.Gly12Asp (G12D).
This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment.
gap junction protein, beta 4, 30.3kDa
, gap junction beta-4 protein
, gap junction membrane channel protein beta 4
, connexin 30.3