anti-GATA Binding Protein 5 (GATA5) 抗体

The protein encoded by GATA5 is a transcription factor that contains two GATA-type zinc fingers. 再加上,我们可以发GATA5 试剂盒 (40)GATA5 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
GATA5 140628 Q9BWX5
GATA5 14464 P97489
GATA5 499951  
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Showing 10 out of 74 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-GATA5 Antibody Titration:  0.2-1 ug/ml  Positive Control:  HT1080 cell lysate Lanes:   Lane 1: 25 ug empty vector transfected H460 cell lysate Lane 2: 25 ug hGATA5 transfected H460 cell lysate  Primary Antibody Dilution:   1:1200  Secondary Antibody:   Anti-rabbit HRP  Secondary Antibody Dilution:   1:3500  Gene Name:   GATA5  Submitted by:   Anonymous 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB WB Suggested Anti-Gata5 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  Mouse Thymus 100 μL Log in to see 2至3个工作日
山羊 非结合性 ELISA, WB ABIN334407 (0.3µg/ml) staining of HepG2 cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6至7个工作日
小鼠 非结合性 WB WB Suggested Anti-GATA5 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:1562500  Positive Control:  SP2/0 cell lysate Host:  Rabbit  Target Name:  GATA5  Sample Tissue:  Mouse Testis  Antibody Dilution:  1ug/ml 100 μL Log in to see 2至3个工作日
小鸡 非结合性 IHC, WB Immunohistochemical analysis of GATA5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with Western blot analysis of GATA5 expression in HepG2 (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 13至14个工作日
大鼠 非结合性 WB Anti- GATA5 antibody, Western blotting All lanes: Anti GATA5  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Rat Brain Tissue Lysate at 50ug Lane 3: Rat Ovary Tissue Lysate at 50ug Predicted bind size: 42KD Observed bind size: 42KD 100 μg Log in to see 4至6个工作日
小鼠 非结合性 WB 100 μg Log in to see 11至14个工作日
山羊 非结合性 ELISA, WB 100 μg Log in to see 11至14个工作日
小鼠 非结合性 ELISA, WB Red: Control Antigen (100ng);Purple: Antigen (10ng);Green: Antigen (50ng);Blue: Antigen (100ng); Dilution: 1/10000 Figure 1: Western blot analysis using GATA5 mAb against human GATA5 (AA: 168-391) recombinant protein. (Expected MW is 49.6 kDa)  Dilution: 1/500 - 1/2000 100 μL Log in to see 8至11个工作日
Cow 非结合性 WB 50 μg Log in to see 11至14个工作日

引用最多的anti-GATA5 抗体

  1. Human Polyclonal GATA5 Primary Antibody for ELISA, WB - ABIN188675 : Belinsky, Liechty, Gentry, Wolf, Rogers, Vu, Haney, Kennedy, Hirsch, Miller, Franklin, Herman, Baylin, Bunn, Byers: Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort. in Cancer research 2006 (PubMed)

  2. Human Monoclonal GATA5 Primary Antibody for ELISA, WB - ABIN969170 : Hellebrekers, Lentjes, van den Bosch, Melotte, Wouters, Daenen, Smits, Akiyama, Yuasa, Sanduleanu, Khalid-de Bakker, Jonkers, Weijenberg, Louwagie, van Criekinge, Carvalho, Meijer, Baylin, Herman et al.: GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer. ... in Clinical cancer research : an official journal of the American Association for Cancer Research 2009 (PubMed)


Human GATA Binding Protein 5 (GATA5) interaction partners

  1. findings show that GATA5 mutations, in addition to heart diseases, can result in congenital abnormalities of the female genitourinary tract in humans

  2. A multivariate regression model revealed that the effects of both the promoter methylation and the exonic SNPs in GATA5 were independent.This interaction between GATA5 variants and GATA5 promoter methylation indicates that the association of either factor with gastric disease progression is modified by the other

  3. These results suggest that the induction of GATA-6 dysfunction may be more effective for chemotherapy for colorectal cancer, although the mechanism underlying the synergistic effect of 5-FU and anisomycin remains unknown.

  4. The Correlation between GATA5, WT1 and PAX5 methylation and clinical/histological parameters is suggestive of applicability of these markers in non-invasive (epi)genetic testing in hepatocellular carcinoma (HCC).

  5. we identified gene promoter methylation signatures (WT1, MSH6, GATA5 and PAX5) that are strongly correlated to, and can have a predictive value for the clinical outcome of oral squamous cell carcinoma patients

  6. Evidence supporting a genetic basis includes the autosomal dominance of Bicuspid aortic valve inheritance patterns, and the identification of mutations in GATA binding protein 5 transcription factor.

  7. Transcriptomic analysis of human microvascular endothelial cells with GATA5 knockdown reveals that GATA5 affects several genes and pathways critical for endothelial function.

  8. This study firstly links GATA5 mutation to DCM, which provides novel insight into the molecular mechanisms of DCM, suggesting a potential molecular target for the prenatal prophylaxis and allele-specific treatment of DCM.

  9. Promoter hypermethylation is an important mechanism of the transcriptional inactivation of GATA5 in invasive ductal breast carcinoma.

  10. A combination of GATA5 and SFRP2 methylation could be promising as a marker for the detection and diagnosis of colorectal cancers and adenomas.

  11. A new potentially pathogenic variant in GATA5 contributes to the development of bicuspid aortic valve syndrome.

  12. DSVs in the GATA5 gene promoter may increase the susceptibility to the development of VSD as a risk factor.

  13. Rare sequence variants, p.Gln3Arg and p.Leu233Pro, in GATA5 are associated with human bicuspid aortic valve.

  14. study provides genetic evidence on the association of GATA5 loss-of-function mutations with enhanced susceptibility to bicuspid aortic valve (BAV), providing novel insight into the molecular mechanism involved in human BAV

  15. Results of this study showed an association of somatic GATA5 mutations with TOF, providing further insight into the underlying molecular mechanism of TOF.

  16. Epigenetic alterations in GATA family members may be associated with aggressive tumor phenotypes in renal cell cancer

  17. Reduced GATA5 mRNA levels are associated with a poor clinical outcome, indicating a possible role of GATA5 for the development of aggressive clear cell renal cell carcinoma.

  18. GATA5, possibly through upregulation of eNOS, plays a role in the development of aortic dilatation in patients with unicuspid and bicuspid aortic valves.

  19. GATA5 mutations were associated with congenital heart disease.

  20. The findings expand the spectrum of GATA5 mutations linked to atrial fibrillation and provide novel insights into the molecular mechanism involved in the pathogenesis of atrial fibrillation

Mouse (Murine) GATA Binding Protein 5 (GATA5) interaction partners

  1. GATA5 is expressed in microvascular endothelial cells and its inactivation in mice leads to vascular endothelial dysfunction and hypertension.

  2. GATA transcription factors are repressors of hedgehog signaling, and NKX3.2 maintains the ability of sclerotomal cells to express SHH transcriptional targets in the presence of BMP signals by repressing the induction of Gata4/5/6

  3. Gata5 deficiency induces airway hyperresponsiveness, at least in part, by blunting apoE and increasing IL-13 expression.

  4. Expression of Gata5 very efficiently promotes cardiomyocyte fate from murine embryonic stem cells.

  5. USF1 transactivates GATA5 expression by binding to the E-box in its promoter

  6. compound Gata4/Gata5 and Gata5/Gata6 mutants die embryonically or perinatally due to severe congenital heart defects

  7. Results unravel a critical cell-autonomous role for endocardial Gata5 in aortic valve formation and identify GATA5 as a potential gene responsible for congenital heart disease in humans.

  8. These results demonstrate functional redundancy between Gata4 and Gata5 during cardiac development and implicate Gata5 as a candidate modifier gene for congenital heart disease.

  9. data reveal that transcription factor GATA5 is required for differentiation of cardiogenic precursors into endothelial endocardial cells

  10. collaboration between GATA-6 and GATA-4, or GATA-6 and GATA-5 which can substitute for GATA-4, is involved in the perception of differentiation cues by embryonic stem cells in their determination of endoderm lineage

  11. GATA5 is not expressed in Sertoli cells. Transfected GATA5 & GATA4 work together with human AR to activate human PSA transcription.

  12. Report alternative promoter and GATA5 transcripts in mouse.

Xenopus laevis GATA Binding Protein 5 (GATA5) interaction partners

  1. Data show that GATA4 or 6 regulate both cardiogenic potential and subsequent cardiomyocyte differentiation but that GATA5 is involved in regulating cardiomyocyte differentiation.

Zebrafish GATA Binding Protein 5 (GATA5) interaction partners

  1. identified GATA5 as a SUMO substrate, and lysine 324 (K324) and lysine 360 (K360) as two major modification sites

  2. specification of cardiac fate downstream of gata5/6 involves activation of the tmem88a gene to constrain WNT signaling and expand the number of cardiac progenitors.

  3. Overexpression of smarcd3b and gata5 in zebrafish results in an enlarged heart, whereas combinatorial loss of cBAF components inhibits cardiac differentiation, demonstrating that Smarcd3b and Gata5 can induce a primitive, progenitor cell-like state.

  4. First evidence for a regulatory function for gata5 in the formation of Kupffer's vesicle and left-right patterning.

  5. Grl forms a complex with Gata5 through the carboxyl region and can repress Gata5-mediated transcription.

  6. Data show that GATA4 knockdown only affects cardiac marker expression in the absence of either GATA5 or GATA6, suggesting redundancy in this family during myocardial development.

  7. the gata5 genes are redundant for specification of cardiomyocytes.

GATA5 抗原简介


The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity.

Gene names and symbols associated with GATA5

  • GATA binding protein 5 (GATA5) 抗体
  • GATA binding protein 5 (Gata5) 抗体
  • GATA binding protein 5 (gata5) 抗体
  • GATA binding protein 5 S homeolog (gata5.S) 抗体
  • bb379o24.1 抗体
  • cb634 抗体
  • fau/gata5 抗体
  • gata-4a 抗体
  • GATA-5 抗体
  • gata-5a 抗体
  • gata5 抗体
  • GATAS 抗体
  • gta5 抗体
  • xGATA-5 抗体
  • xGATA-5a 抗体
  • xGATA-5b 抗体
  • xGATA5 抗体
  • xGATA5a 抗体
  • xGATA5b 抗体

Protein level used designations for GATA5

GATA binding factor-5 , GATA-binding factor 5 , GATA-binding protein 5 , transcription factor GATA-5 , Transcription factor GATA-5 (GATA binding factor-5) , GATA-5 transcription factor , GATA binding protein 5 , GATA-binding factor 5-A , transcription factor xGATA-5a , fau , faust

140628 Homo sapiens
14464 Mus musculus
396391 Gallus gallus
458389 Pan troglodytes
485961 Canis lupus familiaris
496852 Xenopus (Silurana) tropicalis
499951 Rattus norvegicus
504784 Bos taurus
100225872 Taeniopygia guttata
398144 Xenopus laevis
100719097 Cavia porcellus
100820750 Ovis aries
30482 Danio rerio
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