GATA5 抗体 (AA 1-397)
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北京 101111
Quick Overview for GATA5 抗体 (AA 1-397) (ABIN3031034)
抗原
See all GATA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-397
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原理
- GATA5 Antibody
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纯化方法
- Antigen affinity
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免疫原
- Human partial recombinant protein (AA 1-397) was used as the immunogen for this GATA5 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the GATA5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the GATA5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- GATA5 (GATA Binding Protein 5 (GATA5))
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别名
- GATA5
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背景
- Transcription factor GATA-5, also named GATAS, is a protein that in humans is encoded by the GATA5 gene. It is mapped to 20q13.33. The protein encoded by this gene is a transcription factor that contains two GATA-type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF-1alpha), and this interaction is essential for cooperative activation of the intestinal lactase-phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. In addition, the expression of GATA5 increased in a human colon cancer cell line within two hours of exposure to sodium butyrate, which induces differentiation.
抗原
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