anti-Formin-Like 2 (FMNL2) 抗体

FMNL2 encodes a formin-related protein. 再加上,我们可以发FMNL2 试剂盒 (4)FMNL2 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
FMNL2 71409 A2APV2
FMNL2 114793 Q96PY5
FMNL2 311033  
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antibodies-online.cn销售最多的anti-FMNL2 抗体

Showing 10 out of 26 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
豚鼠 非结合性 WB WB Suggested Anti-FMNL2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Jurkat cell lysate 100 μL Log in to see 2至3个工作日
$289.00
详细
Cow 非结合性 WB 100 μL Log in to see 2至3个工作日
$289.00
详细
非结合性 ICC, IF, IHC, IHC (p) Immunocytochemistry/ Immunofluorescence: FMNL2 Antibody [NBP1-83901] - Staining of human cell line U-251MG shows positivity in plasma membrane & cytoplasm. Immunohistochemistry-Paraffin: FMNL2 Antibody [NBP1-83901] - Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in glandular cells. 0.1 mL Log in to see 10至13个工作日
$494.38
详细
Cow 非结合性 IHC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with FMNL2 antibody ABIN297065 at 5-10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-FMNL2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. 50 μg Log in to see 11至14个工作日
$484.00
详细
非结合性 WB 50 μg Log in to see 11至14个工作日
$551.83
详细
Chimpanzee 非结合性 IHC (p), WB 50 μg Log in to see 6至8个工作日
$390.50
详细
小鼠 非结合性 ELISA, WB FMNL2 monoclonal antibody (M01), clone 2B4 Western Blot analysis of FMNL2 expression in IMR-32 . Western Blot detection against Immunogen (45.32 KDa) . 100 μg Log in to see 11至12个工作日
$440.00
详细
小鼠 非结合性 WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (45.32 KDa) . Dilution: 1:500~1000 FMNL2 monoclonal antibody (M01), clone 2B4 Western Blot analysis of FMNL2 expression in IMR-32 ( (# ABIN395353 ) Dilution: 1:500~1000 100 μg Log in to see 8至11个工作日
$527.50
详细
非结合性 IHC (p), WB 50 μg Log in to see 12至14个工作日
$673.48
详细
非结合性 WB Western Blot: FMNL2 Antibody [NBP1-79264] - Titration: 1.6 ug/ml Positive Control: human cell lines. Western Blot: FMNL2 Antibody [NBP1-79264] - 1 ug/ml ELISA Titer: 1:62500 Positive Control: Jurkat cell lysate 100 μL Log in to see 8至11个工作日
$488.73
详细

引用最多的anti-FMNL2 抗体

  1. Human Monoclonal FMNL2 Primary Antibody for ELISA, WB - ABIN566725 : Zhu, Liang, Ding: Overexpression of FMNL2 is closely related to metastasis of colorectal cancer. in International journal of colorectal disease 2008 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal FMNL2 Primary Antibody for ICC, IF - ABIN4312213 : Gardberg, Talvinen, Kaipio, Iljin, Kampf, Uhlen, Carpén: Characterization of Diaphanous-related formin FMNL2 in human tissues. in BMC cell biology 2010 (PubMed)
    Show all 2 Pubmed References

更多抗FMNL2的相互作用对抗体

Mouse (Murine) Formin-Like 2 (FMNL2) interaction partners

  1. force generation in lamellipodia strongly depends on FMNL formin activity.

  2. FMNL1 and FMNL2 are required non-redundantly in the repair of damaged myofibrils.

  3. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  4. mDia1-FH2 has an effect on the conformation of actin filaments

Human Formin-Like 2 (FMNL2) interaction partners

  1. FMNL2 knockout cells were characterized by impaired filopodia formation similar to depletion of the Rho GTPase Cdc42.

  2. Data demonstrate that the FMNL2/COMMD10/p65 NF kappaB axis acts as a critical regulator in the maintenance of metastatic phenotypes in colorectal cancer.

  3. Our data proved that RMRP acted as an oncogene LncRNA to promote the expression of KRAS, FMNL2 and SOX9 by inhibiting miR-206 expression in lung cancer. These data suggested that RMRP might serve as a therapeutic target in lung adenocarcinoma

  4. FMNL2 is likely to be generally required in melanoma cells for invasion.

  5. miR-206 functioned as a tumor suppressor in the progression of colorectal cancer(CRC) by targeting FMNL2 and c-MET. Restoration of miR-206 expression may represent a promising therapeutic approach for targeting malignant CRC.

  6. Capping protein and FMNL2 functionally coregulate filament barbed-end assembly.

  7. The two interacting FMNL-Cdc42 heterodimers expose six membrane interaction motifs on a convex protein surface, the assembly of which may facilitate actin filament elongation at the leading edge of lamellipodia and filopodia.

  8. These data establish a role for FMNL2 in the regulation of beta1-integrin and provide a mechanistic understanding of the function of FMNL2 in cancer invasiveness.

  9. MiR-34a was down-regulated in colorectal cancer cells and inversely correlated with FMNL2 and E2F5 expressions. Our study suggests that miR-34a is an important tumor suppressor of CRC progression by targeting FMNL2 and E2F5.

  10. Rac1-induced actin assembly and subsequent AJ formation critically depends on FMNL2.

  11. miR-137, induced by its upstream transcription factor HMGA1, can suppress colorectal cancer cell invasion and metastasis by targeting FMNL2.

  12. Protein N-myristoylation plays critical roles in the cellular morphological changes induced by FMNL2 and FMNL3.

  13. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  14. formin-like 2 expression correlated positively with tumor differentiation (P = .046) and vascular invasion (P = .008). Patients whose tumors had lower formin-like 2 expression had shorter overall survival times

  15. Findings identify a novel EMT and tumor promoting function for FMNL2, which is involved in TGF-beta-induced EMT and colorectal carcinoma cell invasion via Smad3 effectors, or in collaboration with MAPK/MEK pathway.

  16. a novel regulatory and functional interaction between RhoC and FMNL2 for modulating cell shape and invasiveness and provide mechanistic insight into RhoC-specific signalling events.

  17. FMNL2 may play an important role in the metastasis of CRC and may be a useful marker for metastasis of CRC.

FMNL2 抗原简介

蛋白简介

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.

Gene names and symbols associated with anti-Formin-Like 2 (FMNL2) 抗体

  • formin-like 2 (Fmnl2) 抗体
  • formin like 2 (FMNL2) 抗体
  • formin-like protein 2 (LOC476151) 抗体
  • formin-like 2a (fmnl2a) 抗体
  • formin like 2 (Fmnl2) 抗体
  • 5430425K04Rik 抗体
  • FHOD2 抗体
  • fmnl2 抗体
  • Man 抗体
  • si:ch211-279a7.1 抗体

Protein level used designations for anti-Formin-Like 2 (FMNL2) 抗体

formin-like domain containing protein MAN , formin-like protein 2 , protein Man , formin homology 2 domain containing 2 , formin homology 2 domain-containing protein 2 , formin-like 2

GENE ID SPECIES
71409 Mus musculus
114793 Homo sapiens
459663 Pan troglodytes
476151 Canis lupus familiaris
695391 Macaca mulatta
771739 Gallus gallus
100006456 Danio rerio
100543936 Meleagris gallopavo
311033 Rattus norvegicus
788312 Bos taurus
100723045 Cavia porcellus
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