(Feline Leukemia Virus Subgroup C Cellular Receptor Family, Member 2 (FLVCR2))
This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.[provided by RefSeq, Aug 2010].
Duffy, Shing, Saraon, Berger, Eiden, Wilde, Tailor: "The Fowler syndrome-associated protein FLVCR2 is an importer of heme." in: Molecular and cellular biology, Vol. 30, Issue 22, pp. 5318-24, (2010) (PubMed).
Brasier, Tikellis, Xuereb, Craigie, Casley, Kovacs, Fudge, Kalnins, Cooper, Wookey: "Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis." in: Experimental cell research, Vol. 293, Issue 1, pp. 31-42, (2004) (PubMed).
Aliases for FLVCR2 抗体
feline leukemia virus subgroup C cellular receptor family member 2 (FLVCR2) 抗体 feline leukemia virus subgroup C cellular receptor family, member 2 (Flvcr2) 抗体 feline leukemia virus subgroup C cellular receptor 2 (Flvcr2) 抗体 C14orf58 抗体 CCT 抗体 EPV 抗体 Flvcr2 抗体 FLVCRL14q 抗体 MFSD7C 抗体 PVHH 抗体